Frederick R. Maxfield
Maxfield, Frederick R.
VIAF ID: 162696852 (Personal)
Permalink: http://viaf.org/viaf/162696852
Preferred Forms
- 100 0 _ ‡a Frederick R. Maxfield
- 100 1 _ ‡a Maxfield, Frederick R.
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- 100 1 _ ‡a Maxfield, Frederick R.
- 100 1 _ ‡a Maxfield, Frederick R.
- 100 1 _ ‡a Maxfield, Frederick R.
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4xx's: Alternate Name Forms (2)
5xx's: Related Names (2)
Works
Title | Sources |
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Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization. | |
Analysis of cholesterol trafficking with fluorescent probes | |
Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells | |
Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling | |
Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium. | |
Cell-cell signaling in vertebrate development, 1993: | |
Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells | |
Cholesterol, the central lipid of mammalian cells | |
Collection of insulin, EGF and α2-Macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization | |
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. | |
Comment on 'Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol' | |
Cyclized dipeptide model for a beta-bend | |
The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis. | |
Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling | |
Development of a novel, cell-based chemical screen to identify inhibitors of intraphagosomal lipolysis in macrophages. | |
Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells | |
Digestive exophagy: Phagocyte digestion of objects too large for phagocytosis | |
The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent. | |
Effect of primary amines on interferon action | |
Effects of buffering intracellular free calcium on neutrophil migration through three-dimensional matrices | |
Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes. | |
Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary | |
Elevated plasma membrane cholesterol content alters macrophage signaling and function. | |
The endocytic pathway in microglia during health, aging and Alzheimer's disease | |
Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. | |
Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to thetrans-Golgi Network and a Subpopulation of Late Endosomes | |
An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. | |
Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits | |
Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells. | |
Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation. | |
Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin. | |
Flotillas of lipid rafts fore and aft. | |
Fluorescence imaging in living animals. Focus on "Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy". | |
Immunolocalization of Acyl-Coenzyme A:CholesterolO-Acyltransferase in Macrophages | |
Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts | |
The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells. | |
Insulin stimulation of amino acid transport in isolated rat hepatocytes is independent of hormone internalization | |
Intracellular sterol transport and distribution. | |
Local and global changes in cytosolic free calcium in neutrophils during chemotaxis and phagocytosis | |
Lysosomes : biology, diseases, and therapeutics | |
Lysosomes (Maxfield) | |
Membrane domains. | |
Membrane lipid organization is critical for human neutrophil polarization. | |
Membrane transport in the endocytic pathway | |
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor | |
Microtubule asymmetry during neutrophil polarization and migration. | |
Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol. | |
Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation | |
Multiphoton microscopy for structure identification in human prostate and periprostatic tissue: implications in prostate cancer surgery | |
Multiphoton microscopy in the evaluation of human bladder biopsies | |
Multiphoton microscopy of prostate and periprostatic neural tissue: a promising imaging technique for improving nerve-sparing prostatectomy | |
A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele | |
Niemann‐Pick type C disease: molecular mechanisms and potential therapeutic approaches | |
A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75NTR-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo | |
Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. | |
Oxalic acid alters intracellular calcium in endothelial cells | |
Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays. | |
Preparation of solutions with free calcium concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid | |
Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control | |
Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy | |
Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts | |
Regulation of endocytic processes by pH. | |
Regulation of leukocyte locomotion by Ca2+. | |
Role of endosomes and lysosomes in human disease. | |
SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. | |
Sphingosine kinases are not required for inflammatory responses in macrophages | |
STARD4 abundance regulates sterol transport and sensing | |
STARD4 Membrane Interactions and Sterol Binding. | |
Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect. | |
Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis | |
Transferrin receptor containing the SDYQRL motif of TGN38 causes a reorganization of the recycling compartment but is not targeted to the TGN | |
Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones | |
Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. | |
Treatment of Niemann--pick type C disease by histone deacetylase inhibitors. | |
The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin Cytoskeleton, Rho family GTPases, and myosin ATPase activity. | |
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. | |
Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle | |
Yolk platelets in Xenopus oocytes maintain an acidic internal pH which may be essential for sodium accumulation |