Mak, Tak. W., 1945-
Mak, Tak W.
Tak Wah Mak Canadian biochemist
VIAF ID: 110577691 (Personal)
Permalink: http://viaf.org/viaf/110577691
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200 _ | ‡a Mak ‡b Tak W. ‡f 1945-....
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100 1 _ ‡a Mak, Tak W.
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100 1 _ ‡a Mak, Tak W. ‡d 1945-
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100 1 _ ‡a Mak, Tak W. ‡d 1945-
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100 1 0 ‡a Mak, Tak W., ‡d 1945-
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100 1 _ ‡a Mak, Tak W., ‡d 1945-....
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100 1 _ ‡a Mak, Tak. W., ‡d 1945-
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100 0 _ ‡a Tak Wah Mak ‡c Canadian biochemist
4xx's: Alternate Name Forms (20)
Works
Title | Sources |
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IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology |
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AIDS : 10 years later |
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The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses |
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Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. |
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Biochemical and biophysical studies of three variants of Mengo encephalomyelitis virus. |
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c-Rel but not NF-κB1 is important for T regulatory cell development |
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Cancer, perspective for control proceedings of an international symposium, held in Beijing, China, August 18 - 21, 1985 |
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CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation. |
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Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress |
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Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death |
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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity |
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The CD83 reporter mouse elucidates the activity of the CD83 promoter in B, T, and dendritic cell populations in vivo |
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Cellular and molecular biology of neoplasia proceedings of a symposium held at Honey Harbor, Ontario, Canada, October 2-6, 1983 |
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Cellular FLICE-inhibitory protein is required for T cell survival and cycling |
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Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner |
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Choline acetyltransferase-expressing T cells are required to control chronic viral infection |
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Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses |
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Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation |
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Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection |
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DIPG-13. A NOVEL MOUSE MODEL REVEALS UNEXPECTED MECHANISMS OF ACTION OF ACVR1 MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA |
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The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. |
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Environment |
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Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway |
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Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis |
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Fcmr regulates mononuclear phagocyte control of anti-tumor immunity |
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Fighting cancers from within: augmenting tumor immunity with cytokine therapy |
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The gene knockout factsbook |
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Generation and characterization of the Anp32e-deficient mouse |
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Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression |
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Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation. |
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Handbook of immune response genes |
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Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development |
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HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53 |
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HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. |
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Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. |
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IDH1 |
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IDH1 deficiency attenuates gluconeogenesis in mouse liver by impairing amino acid utilization |
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Idh1 mutations contribute to the development of T-cell malignancies in genetically engineered mice |
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IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics |
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The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development |
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The inducible costimulator plays the major costimulatory role in humoral immune responses in the absence of CD28. |
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Involvement of Toso in activation of monocytes, macrophages, and granulocytes |
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iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS |
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Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway |
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K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. |
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Largen: a molecular regulator of mammalian cell size control |
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Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury |
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Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis |
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Molecular mechanisms and their clinical application in malignancies |
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Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 |
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Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation |
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Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas |
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Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. |
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Mutations d'IDH2, TET2 et DNMT3A dans les lymphomes T périphériques : de la biologie à la clinique |
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n82021572 |
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Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity |
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The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells |
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Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo |
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Onco-metabolomics ; a new clue to understand carcinogenesis, cancer biology and to develop novel diagnostics and therapeutics : extended abstracts for the 46th International Symposium of the Princess Takamatsu Cancer Research Fund, 2015 : November 17-19, 2015 Tokyo, Japan |
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p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1 |
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Pillars Article: Requirement for the Transcription Factor LSIRF/IRF4 for Mature B and T Lymphocyte Function. Science. 1997. 275: 540-543 |
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Primer to the immune response |
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RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. |
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Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1 |
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RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis |
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RIP2 contributes to Nod signaling but is not essential for T cell proliferation, T helper differentiation or TLR responses |
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Role of SODD in Regulation of Tumor Necrosis Factor Responses |
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Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4 |
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Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle |
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Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis |
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Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3) |
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Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death |
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Sym. on Cellular & Molecular Bio. of Hemopoietic Stem Cell Diff. (1981 : Honey Harbor, Ont.). Cellular & molecular bio. of hemopoietic stem cell differentiation, 1982 (a.e.) |
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The T-cell receptors |
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TAp73 is required for spermatogenesis and the maintenance of male fertility |
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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions |
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TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation |
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Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development. |
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TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice |
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Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity. |
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XB130 deficiency affects tracheal epithelial differentiation during airway repair |
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YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma |
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