Ramanujan Shankar Hegde Group Leader, MRC Laboratory of Molecular Biology, University of Cambridge
Hegde, Ramanujan
VIAF ID: 88425460 (Personal)
Permalink: http://viaf.org/viaf/88425460
Preferred Forms
4xx's: Alternate Name Forms (3)
Works
| Title | Sources |
|---|---|
| The concept of translocational regulation |
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| Coordinate control of translation and localization of Vg1 mRNA in Xenopus oocytes |
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| Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel |
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| Cytosolic aggregates perturb the degradation of nontranslocated secretory and membrane proteins |
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| Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6 |
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| Cytotoxicity of Aberrant Proteins |
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| Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes |
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| Design principles of protein biosynthesis-coupled quality control |
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| Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER |
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| The efficiency of protein compartmentalization into the secretory pathway |
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| EMC Is Required to Initiate Accurate Membrane Protein Topogenesis |
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| An ER complex of ODR-4 and ODR-8/Ufm1 specific protease 2 promotes GPCR maturation by a Ufm1-independent mechanism |
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| The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis |
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| Formation of stacked ER cisternae by low affinity protein interactions |
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| How cells make membrane proteins, 2023: |
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| How much do rural Hispanics know about the adverse health risks of smoking? |
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| Identification of a targeting factor for posttranslational membrane protein insertion into the ER |
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| Intracellular Ca(2+) release via the ER translocon activates store-operated calcium entry |
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| Ionic effects on bumetanide binding to the activated Na/K/2Cl cotransporter: selectivity and kinetic properties of ion binding sites |
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| The life of proteins: the good, the mostly good and the ugly |
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| Lighting up the stressed ER. |
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| Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation |
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| Local synthesis and disposal |
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| Mechanism of ribosome stalling during translation of a poly(A) tail |
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| Mechanistic basis for a molecular triage reaction |
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| Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors |
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| Msp1: patrolling mitochondria for lost proteins |
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| A multistep, ATP-dependent pathway for assembly of human immunodeficiency virus capsids in a cell-free system |
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| Mutant PrPSc conformers induced by a synthetic peptide and several prion strains |
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| The organization of engaged and quiescent translocons in the endoplasmic reticulum of mammalian cells |
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| Prion protein trafficking and the development of neurodegeneration |
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| Prions and retroviruses: an endosomal rendezvous? |
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| Protection from cytosolic prion protein toxicity by modulation of protein translocation |
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| Protein targeting and degradation are coupled for elimination of mislocalized proteins |
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| Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo |
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| Rational design and evaluation of FRET experiments to measure protein proximities in cells |
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| Reconstitution of a minimal ribosome-associated ubiquitination pathway with purified factors |
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| Regulation of basal cellular physiology by the homeostatic unfolded protein response |
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| Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store |
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| A ribosome-associating factor chaperones tail-anchored membrane proteins |
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| Ribosome collisions trigger cis-acting feedback inhibition of translation initiation |
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| The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon |
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| The role of p58IPK in protecting the stressed endoplasmic reticulum |
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| Secretory and membrane protein biosynthesis in health and disease, 2009: |
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| Secretory protein profiling reveals TNF-α inactivation by selective and promiscuous Sec61 modulators |
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| Selective processing and metabolism of disease-causing mutant prion proteins |
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| Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol |
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| Short circuiting stress protein expression via a tyrosine kinase inhibitor, herbimycin A. |
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| Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein |
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| Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome |
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| Structural basis for stop codon recognition in eukaryotes |
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| Structure and assembly pathway of the ribosome quality control complex |
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| Structure of the Sec61 channel opened by a signal sequence |
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| Structures of the scanning and engaged states of the mammalian SRP-ribosome complex |
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| Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane |
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| Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway |
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| The surprising complexity of signal sequences |
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| Tail-anchored membrane protein insertion into the endoplasmic reticulum |
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| Target Selection during Protein Quality Control |
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| Targeting and beyond: new roles for old signal sequences |
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| Toward a structural understanding of co-translational protein translocation |
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| Translation stress and collided ribosomes are co-activators of cGAS |
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| Transmembrane domain modulates sorting of membrane proteins in Toxoplasma gondii |
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| Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition |
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| Transmissible and genetic prion diseases share a common pathway of neurodegeneration |
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| TTC5 mediates autoregulation of tubulin via mRNA degradation |
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| UBE2O is a quality control factor for orphans of multiprotein complexes. |
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| Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. |
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| A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation |
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| ZNF598 Is a Quality Control Sensor of Collided Ribosomes |
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