Valcárcel, J. Juan
Juan Valcárcel researcher
Valcarcel, Juan
![Sudoc [ABES], France](/viaf/images/flags/SUDOC.png "Sudoc [ABES], France")
VIAF ID: 86943910 (Personal)
Permalink: http://viaf.org/viaf/86943910
Preferred Forms
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Juan Valcárcel
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researcher
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Valcarcel, Juan
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100 1 _ ‡a Valcárcel, J. ‡q (Juan)
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100 1 0
‡a
Valcárcel, J.
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Juan
4xx's: Alternate Name Forms (6)
Works
| Title | Sources |
|---|---|
| Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells |
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| Biochemical function of female-lethal |
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| Characterization of SF3B1 mutation in chronic lymphocytic leukemia and the role of new splicing modulators |
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| Characterization of synthetic lethality between MYC activation and splicing inhibition in an immortalized cell line : roles of alternative splicing |
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| Competition by the masses |
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| The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitro |
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| Contribution of U2AF1, NCBP1 and eIF4A3 to the control of pluripotency maintenance and cell fate determination |
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| CPEB1 coordinates alternative 3′-UTR formation with translational regulation |
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| Delineating a requirement for Survival of Motor Neuron (SMN) protein in skeletal muscle tissue |
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| Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins |
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| Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster. |
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| The Drosophila fl(2)d gene, required for female-specific splicing of Sxl and tra pre-mRNAs, encodes a novel nuclear protein with a HQ-rich domain |
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| The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA |
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| Dual function for U2AF(35) in AG-dependent pre-mRNA splicing |
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| Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1 |
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| The expanding transcriptome: the genome as the 'Book of Sand' |
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| Exploring the role of differential expression of splicing factors and regulators in tissue-specific alternative splicing |
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| Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing |
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| Functional impact of frequent cancer mutations in the splicing regulatory protein RBM10 and discovery of cancer relevant targets |
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| Functional splicing network reveals extensive regulatory potential of the core spliceosomal machinery |
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| Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells |
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| Haploinsufficiency, rather than the effect of an excessive production of soluble CD95 (CD95{Delta}TM), is the basis for ALPS Ia in a family with duplicated 3' splice site AG in CD95 intron 5 on one allele |
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| hnRNP A1 proofreads 3' splice site recognition by U2AF. |
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| Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG. |
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| Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected] |
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| Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks |
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| Links between chromatin structure and regulation of alternative pre-mRNA splicing in mammalian cells |
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| Molecular biology: spliceosome meets telomerase. |
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| Molecular mechanisms of alternative splicing regulation by antitumor drugs targeting U2 snRNP |
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| Molecular mechanisms of regulation of exon definition through splicing silencers and cognate factors |
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| Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF |
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| Multiple forms of the U2 small nuclear ribonucleoprotein auxiliary factor U2AF subunits expressed in higher plants |
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| Mutations primarily alter the inclusion of alternatively spliced exons |
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| Nuclear transport of influenza virus polymerase PA protein. |
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| Nucleocytoplasmic shuttling of heterodimeric splicing factor U2AF |
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| Nucleosome positioning as a determinant of exon recognition |
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| Optimization of oligonucleotide-based DNA microarrays. |
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| The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches |
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| Post-transcriptional regulation: the dawn of PTB. |
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| Powering a two-stroke RNA engine. |
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| Promoter-like epigenetic signatures in exons displaying cell type-specific splicing |
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| The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. |
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| Reconstruction of composite regulator-target splicing networks from high-throughput transcriptome data |
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| Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A |
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| Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition |
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| Regulation of FAS exon definition and apoptosis by the Ewing sarcoma protein |
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| Regulation of NUMB alternative splicing by RBM10 and control of cancer cell proliferation |
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| Relationship between nucleosome positioning and progesterone-induced alternative splicing in breast cancer cells |
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| RNA. Prescribing splicing |
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| RNA processing: Redrawing the map of charted territory |
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| RNA splicing contributes to the generation of mature mRNAs of Borna disease virus, a non-segmented negative strand RNA virus |
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| RNAtomy of the Spliceosome's heart |
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| The role of histone modifications in the regulation of alternative splicing during epithelial-to-mesenchymal transition. |
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| Role of six single nucleotide polymorphisms, risk factors in coronary disease, in OLR1 alternative splicing |
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| Sequential recognition of the pre-mRNA branch point by U2AF65 and a novel spliceosome-associated 28-kDa protein |
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| A simple principle to explain the evolution of pre-mRNA splicing |
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| The spliceosome as a target of novel antitumour drugs |
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| The Spliceosome: The Ultimate RNA Chaperone and Sculptor |
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| A splicing mastermind for EMT |
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| Splicing together sister chromatids |
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| SRRM3 regulates a subprogram of highly sensitive microexons important for pancreatic endocrine function |
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| Strict 3' splice site sequence requirements for U2 snRNP recruitment after U2AF binding underlie a genetic defect leading to autoimmune disease |
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| Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation |
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| Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1 |
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| Sudemycin K: A Synthetic Antitumor Splicing Inhibitor Variant with Improved Activity and Versatile Chemistry. |
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| Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation. |
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| Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers |
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| Systematic functional analyses of spliceosomal components reveal novel mechanisme of alternative splicing regulation |
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| Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1. |
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| Targeting BRAF mutant pre-mRNA alternative splicing in melanoma |
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| Targeting of U2AF65 to sites of active splicing in the nucleus |
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| Tumor suppressor properties of the splicing regulatory factor RBM10. |
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| Two isoforms of the T-cell intracellular antigen 1 (TIA-1) splicing factor display distinct splicing regulation activities. Control of TIA-1 isoform ratio by TIA-1-related protein |
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| U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites |
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| U2AF-homology motif interactions are required for alternative splicing regulation by SPF45 |
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| U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction |
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| Unweaving the meanings of messenger RNA sequences |
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| UPF. Directori (en línia), 25 febr. 2008 |
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| Viral cell biology: Influenza raids the splicing store |
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| Workshop on "From Transcript to Protein" : mRNA Processing, Transport and Translation |
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