Charles Brenner American biologist
Brenner, Charles, 1961-
Brenner, Charles
Brenner, Charles, généticien
![Sudoc [ABES], France](/viaf/images/flags/SUDOC.png "Sudoc [ABES], France")
VIAF ID: 79193080 (Personal)
Permalink: http://viaf.org/viaf/79193080
Preferred Forms
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Brenner
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Charles
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Brenner, Charles
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Brenner, Charles
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1961-
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Brenner, Charles,
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1961-
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100 1 _ ‡a Brenner, Charles, ‡d 1961-
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100 1 _ ‡a Brenner, Charles, ‡d 1961-
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100 1 _
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Brenner, Charles,
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généticien
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100 0 _
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Charles Brenner
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American biologist
4xx's: Alternate Name Forms (12)
Works
| Title | Sources |
|---|---|
| Boosting NAD to spare hearing |
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| Calorie restriction-mediated replicative lifespan extension in yeast is non-cell autonomous |
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| Catalysis in the nitrilase superfamily |
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| Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance |
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| Changes in chemistry and biochemistry education: creative responses to medical college admissions test revisions in the age of the genome |
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| Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging |
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| Condensing the RNA world |
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| Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae |
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| Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1 |
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| Coronavirus and PARP expression dysregulate the NAD Metabolome: a potentially actionable component of innate immunity |
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| Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers |
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| Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding |
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| Desperately seeking Flexner: time to reemphasize basic science in medical education |
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| Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans |
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| Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors |
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| Disease-associated mutations inactivate AMP-lysine hydrolase activity of Aprataxin |
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| Effects of exercise and a modulation of NAD metabolism on cardiac and skeletal muscle function in the context of dilated cardiomyopathy. |
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| Effets de l'exercice et d'une modulation du métabolisme du NAD sur la fonction cardiaque et musculaire dans la cardiomyopathie dilatée |
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| Eukaryotic NAD+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase |
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| Evolution of NAD Biosynthetic Enzymes |
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| Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast |
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| Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer |
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| FHA-RING ubiquitin ligases in cell division cycle control |
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| FHIT |
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| Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substrates |
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| Fhitness and cancer in the mouse |
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| Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit |
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| GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction |
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| Hint2, a mitochondrial apoptotic sensitizer down-regulated in hepatocellular carcinoma |
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| The histidine triad superfamily of nucleotide-binding proteins |
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| Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside. |
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| KRAS-driven miR-29b expression is required for tumor suppressor gene silencing |
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| Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1. |
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| Letting off electrons to cope with metabolic stress |
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| Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring |
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| Metabolism: Targeting a fat-accumulation gene |
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| Microbial NAD metabolism: lessons from comparative genomics |
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| Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications |
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| Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity |
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| NAD as a genotype-specific drug target |
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| NAD+ metabolism in health and disease |
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| NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity |
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| New Tripodal, “Supercharged” Analogues of Adenosine Nucleotides: Inhibitors for the Fhit Ap3A Hydrolase |
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| Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol-Related Liver Disease |
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| Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. |
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| Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration |
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| Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism |
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| Nicotinamide riboside is uniquely and orally bioavailable in mice and humans |
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| Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. |
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| Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice |
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| Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy. |
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| Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. |
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| Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder |
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| Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition |
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| Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans |
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| NNMT: A Bad Actor in Fat Makes Good in Liver. |
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| Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding |
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| Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside |
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| Nrt1 and Tna1-independent export of NAD+ precursor vitamins promotes NAD+ homeostasis and allows engineering of vitamin production |
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| On the nonspecific degradation of NAD+ to nicotinamide riboside |
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| Oncogenomics, c2004: |
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| p53 activation by knockdown technologies |
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| Pharmacological bypass of NAD salvage pathway protects neurons from chemotherapy-induced degeneration |
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| PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma |
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| Pterostilbene raises low density lipoprotein cholesterol in people |
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| Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein |
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| Quantification of protein copy number in yeast: the NAD+ metabolome |
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| Quantitative assessment of enzyme specificity in vivo: P2 recognition by Kex2 protease defined in a genetic system |
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| Recent progress in the study of the intracellular functions of diadenosine polyphosphates |
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| The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1 |
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| The reported human NADsyn2 is ammonia-dependent NAD synthetase from a pseudomonad |
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| Rethinking Premedical and Health Professional Curricula in Light of MCAT 2015 |
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| RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation |
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| RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis. |
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| Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1. |
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| Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults |
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| Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis |
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| Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages |
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| Stereochemical analysis of diastereomeric 1,3-bis(adenosine-5'-O-phosphorothioyl)glycerols |
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| Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease |
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| Subtleties among subtilases. The structural biology of Kex2 and furin-related prohormone convertases |
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| Suppression of TET1-dependent DNA demethylation is essential for KRAS-mediated transformation |
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| Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions. |
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| Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD(+) Metabolites |
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| Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans |
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| Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3 |
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| Why Is Mom Stressed: Homeorhesis as the Potential Problem and Nicotinamide Riboside as the Potential Solution |
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| Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination |
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