Virtual International Authority File


Workman, Paul BIBSYS NII (Japan) Sudoc [ABES], France National Library of the Netherlands National Library of France

Paul Workman biologist Wikidata

Workman, P. (Paul) Library of Congress/NACO National Library of Israel

Workman, P. ISNI

VIAF ID: 76485193 (Personal)


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Title Sources
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1 Wikidata
AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity Wikidata
Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells. Wikidata
BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. Wikidata
Cancer surveys Sudoc [ABES], France
Co-Crystalization and In Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors Wikidata
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone Wikidata
Critical parameters in targeted drug development: the pharmacological audit trail Wikidata
Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766). Wikidata
The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design Wikidata
Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19 Wikidata
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70. Wikidata
Finding the needle in the haystack: why high-throughput screening is good for your health. Wikidata
First-in-human phase I study of pictilisib (GDC-0941), a potent pan-class I phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with advanced solid tumors. Wikidata
The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer Wikidata
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues Wikidata
Maximizing the Therapeutic Potential of HSP90 Inhibitors Wikidata
Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma Wikidata
Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance Wikidata
New approaches in cancer pharmacology, c1992: Sudoc [ABES], France Library of Congress/NACO National Library of Israel
New molecular targets for cancer chemotherapy BIBSYS Sudoc [ABES], France Library of Congress/NACO
Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways Wikidata
Nitrate of soda in the nutrition of the tomato Sudoc [ABES], France
Optimization of Imidazo[4,5- b ]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid Leukemia Wikidata
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Wikidata
Pharmacokinetic-pharmacodynamic relationships for the heat shock protein 90 molecular chaperone inhibitor 17-allylamino, 17-demethoxygeldanamycin in human ovarian cancer xenograft models Wikidata
Pharmacokinetics and cancer chemotherapy Sudoc [ABES], France National Library of France Library of Congress/NACO
Principles of Molecular Oncology Sudoc [ABES], France
A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding. Wikidata
The seventh international conference on chemical modifiers of cancer treatment, Clearwater, Florida, 2-5 February, 1991 Sudoc [ABES], France National Library of the Netherlands
Structural basis of the radicicol resistance displayed by a fungal hsp90 Wikidata
A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera Wikidata
Structure-based drug design : insights from academia and industry Sudoc [ABES], France
Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies Wikidata

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