Paul J Thornalley researcher
Thornalley, Paul J.
Thornalley, P.J.
VIAF ID: 73330654 (Personal)
Permalink: http://viaf.org/viaf/73330654
Preferred Forms
- 100 0 _ ‡a Paul J Thornalley ‡c researcher
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- 100 1 _ ‡a Thornalley, Paul J.
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- 100 1 _ ‡a Thornalley, Paul J.
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- 100 1 _ ‡a Thornalley, Paul J.
4xx's: Alternate Name Forms (2)
Works
Title | Sources |
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Increased serum methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes | |
Inhibition of proliferation of human promyelocytic leukaemia HL60 cells by S-d-lactoylglutathione in vitro | |
Inhibitors of glyoxalase I: Design, synthesis, inhibitory characteristics and biological evaluation | |
Intracellular Accumulation of Methylglyoxal by Glyoxalase 1 Knock Down Alters Collagen Homoeostasis in L6 Myoblasts | |
Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration. | |
Isothiocyanates: mechanism of cancer chemopreventive action | |
Measurement of glyoxalase gene expression | |
Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples | |
A mechanism for primaquine mediated oxidation of NADPH in red blood cells | |
Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds. | |
Methylglyoxal, glyoxalases and the development of diabetic complications. | |
Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments | |
Methylglyoxal modification of LDL: proatherogenicity without oxidation opens new paths to prevent cardiovascular disease | |
Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription | |
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy | |
Methylglyoxal-modified arginine residues — a signal for receptor-mediated endocytosis and degradation of proteins by monocytic THP-1 cells | |
Modification of the glyoxalase system in streptozotocin-induced diabetic rats | |
Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology-Involvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy. | |
Negative Association between Erythrocyte Reduced Glutathione Concentration and Diabetic Complications | |
Nepsilon- | |
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone | |
New development in a blood-based diagnostic test for early-stage arthritis. | |
Novel anti-glycation therapeutic agents: glyoxalase I mimetics | |
Optimisation of non-denaturing polyacrylamide gel electrophoretic analysis of glyoxalase I phenotypes in clinical blood samples | |
The oxidation of oxyhaemoglobin by glyceraldehyde and other simple monosaccharides. | |
Oxygen restriction as challenge test reveals early high-fat-diet-induced changes in glucose and lipid metabolism. | |
Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo | |
Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy. | |
Phenyl radical production during the oxidation of phenylhydrazine and in phenylphydrazine-induced haemolysis | |
Population genetics of human glyoxalases | |
Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals | |
Possible role of methylglyoxal and glyoxalase in arthritis | |
Preparation and characterisation of N epsilon-(1-deoxy-D-fructos-1-yl)hippuryl-lysine | |
Preparation of nucleotide advanced glycation endproducts--imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal | |
Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine | |
Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis | |
The production of free radicals during the autoxidation of monosaccharides by buffer ions | |
The production of hydroxyl radicals by adriamycin in red blood cells | |
The production of oxygen-centered radicals by Bacillus-Calmette-Guerin-activated macrophages | |
Profound mishandling of protein glycation degradation products in uremia and dialysis. | |
Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease | |
Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect | |
Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment | |
Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease. | |
Purification and characterisation of glyoxalase II from human red blood cells | |
Purification of major glucosinolates fromBrassicaceae seeds and preparation of isothiocyanate and amine metabolites | |
Quantitation of plasma thiamine, related metabolites and plasma protein oxidative damage markers in children with autism spectrum disorder and healthy controls. | |
Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves. | |
Rapid hydrolysis and slow α,β-dicarbonyl cleavage of an agent proposed to cleave glucose-derived protein cross-links | |
The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins. | |
Reappraisal of putative glyoxalase 1-deficient mouse and dicarbonyl stress on embryonic stem cells in vitro. | |
Redox metabolism and longevity relationships in animals and plants / edited by Christine H. Foyer, Richard Faragher, Paul J. Thornalley. - New York, cop. 2009. | |
Relation of the protein glycation, oxidation and nitration to the osteocalcin level in obese subjects. | |
Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro | |
Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro towards a standardized approach for research on uraemia | |
The role of EUTox in uremic toxin research | |
S-D-lactoylglutathione in resting and activated human neutrophils. | |
Sample Storage Conditions for the Assay of Glyoxalase Activities in Whole Blood Samples | |
Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats. | |
Special edition of Amino Acids of selected papers from the eleventh international symposium on the Maillard reaction, September 16-20, 2012. | |
Stimulation of Suicidal Erythrocyte Death by Methylglyoxal | |
Studies of advanced glycation end products and oxidation biomarkers for type 2 diabetes | |
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro. | |
Study of an Unusual Advanced Glycation End-Product (AGE) Derived from Glyoxal Using Mass Spectrometry | |
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage | |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro. | |
Synthesis and secretion of tumour necrosis factor-alpha by human monocytic THP-1 cells and chemotaxis induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts. | |
Therapy: Vitamin B6, B9 and B12 in diabetic nephropathy--beware | |
Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness | |
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation | |
Unease on the role of glyoxalase 1 in high-anxiety-related behaviour | |
Unraveling the biological roles of reactive oxygen species | |
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity. | |
Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health | |
Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts |