John Q. Trojanowski American medical researcher
Trojanowski, John Q.
VIAF ID: 64257210 (Personal)
Permalink: http://viaf.org/viaf/64257210
Preferred Forms
- 100 0 _ ‡a John Q. Trojanowski ‡c American medical researcher
- 100 0 _ ‡a John Q. Trojanowski ‡c American medical researcher
- 200 _ | ‡a Trojanowski ‡b John Q.
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- 100 1 _ ‡a Trojanowski, John Q.
- 100 1 _ ‡a Trojanowski, John Q. (sparse)
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- 100 1 _ ‡a Trojanowski, John Q.
4xx's: Alternate Name Forms (9)
Works
Title | Sources |
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Frontotemporal dementia with novel tau pathology and a Glu342Val tau mutation | |
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts | |
The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice | |
A model for improving the treatment and care of Alzheimer's disease patients through interdisciplinary research | |
A morphometric study of the endocytosis of wheat germ agglutinin-horseradish peroxidase conjugates by retinal ganglion cells in the rat | |
Neurodegenerative dementias, c2000: | |
The neuropathology of dementia / edited by: Margaret M. Esiri, Virginia M. -Y Lee and John Q. Trojanowski. - Cambridge, 2004. | |
A new consensus report on biomarkers for the early antemortem diagnosis of Alzheimer disease: current status, relevance to drug discovery, and recommendations for future research. | |
The older rabbit as an animal model: implications for Alzheimer's disease | |
A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease | |
The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort | |
The Penn Parkinson's Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson's disease | |
The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases. | |
A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank | |
The power of neuroimaging biomarkers for screening frontotemporal dementia | |
An R5L tau mutation in a subject with a progressive supranuclear palsy phenotype | |
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases | |
A review and rationale for the use of genetically engineered animals in the study of traumatic brain injury | |
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. | |
The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI). | |
The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury | |
Rozpoznawanie i leczenie otępienia z ciałami Lewy'ego : czwarte stanowisko DLB Consortium = Diagnosis and management of dementia with Lewy bodies : fourth consensus report of the DLB Consortium | |
Rubin's pathology : clinicopathologic foundations of medicine | |
The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates | |
The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration | |
The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease | |
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models | |
Therapeutic strategies for the treatment of tauopathies: Hopes and challenges | |
Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. | |
Thorn-shaped astrocytes in the depth of cortical sulci in Western Pacific ALS/Parkinsonism-Dementia complex | |
TMEM106B Effect on cognition in Parkinson disease and frontotemporal dementia | |
TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions | |
The TMEM106B locus and TDP-43 pathology in older persons without FTLD | |
TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways | |
Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U. | |
Toxicity and neuronal infection of a HSV-1 ICP34.5 mutant in nude mice | |
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers | |
Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers | |
Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome | |
The transcriptional activation domain of VP16 is required for efficient infection and establishment of latency by HSV-1 in the murine peripheral and central nervous systems | |
Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin | |
Transfectable and transplantable postmitotic human neurons: a potential "platform" for gene therapy of nervous system diseases | |
Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh Compound B units of brain Aβ amyloid | |
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions | |
Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration | |
Transgenic mouse models of tauopathies: prospects for animal models of Pick's disease | |
The transitional association between β-amyloid pathology and regional brain atrophy | |
Transmission of tauopathy strains is independent of their isoform composition | |
Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats | |
Transplantation of embryonic dopamine neurons for severe Parkinson's disease | |
Transplanted human neurons derived from a teratocarcinoma cell line (NTera-2) mature, integrate, and survive for over 1 year in the nude mouse brain | |
Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging | |
TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease | |
Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury | |
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease | |
Typical and atypical pathology in primary progressive aphasia variants | |
Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies | |
Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies | |
UNC13A polymorphism contributes to frontotemporal disease in sporadic amyotrophic lateral sclerosis | |
Unexpected abundance of pathological tau in progressive supranuclear palsy white matter | |
The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease | |
'Unfolding' pathways in neurodegenerative disease | |
Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice | |
Update on the neuropathological diagnosis of frontotemporal dementias | |
Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice | |
Utility of amyloid PET in the differential diagnosis of dementia: An autopsy-confirmed series | |
Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium | |
Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects | |
Variables associated with hippocampal atrophy rate in normal aging and mild cognitive impairment | |
Variants associated with Gaucher disease in multiple system atrophy | |
Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration | |
Vascular disease and dementias: paradigm shifts to drive research in new directions | |
Ventricular maps in 804 ADNI subjects: correlations with CSF biomarkers and clinical decline | |
Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury. | |
Vulnerability of the neuronal cytoskeleton in aging and Alzheimer disease: widespread involvement of all three major filament systems. | |
Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI). | |
White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration | |
A yeast functional screen predicts new candidate ALS disease genes | |
α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies | |
Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration | |
α-Synuclein modulates tau spreading in mouse brains | |
α-Synuclein pathology in Parkinson's disease and related α-synucleinopathies | |
α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons |