Biotechnologically important biotransformations by CYP106A2 and CYP109E1 from Bacillus megaterium |
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Charakterisierung ausgewählter Cytochrome P450 aus Sorangium cellulosum So ce56 neue potentielle Biokatalysatoren |
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Conversion of resin acids with bacterial cytochromes CYP105A1 and CYP106A2 - structural basics and potential applications |
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Enzymatische Charakterisierung der humanen Aldosteronsynthase (CYP11B2) durch in vitro Untersuchungen sowie Homologiemodellierung und Dockingstudien |
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Hydroxylation of the triterpenoid dipterocarpol with CYP106A2 from Bacillus megaterium |
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Hydroxylierung bioaktiver Naturstoffe mit CYP106A2 aus Bacillus megaterium - Screening, Biokatalyse und Produktcharakterisierung |
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Identification and circumvention of bottlenecks in CYP21A2-mediated premedrol production using recombinant Escherichia coli |
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Identification of a new plasmid-encoded cytochrome P450 CYP107DY1 from Bacillus megaterium with a catalytic activity towards mevastatin. |
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Identifizierung und Charakterisierung neuer Cytochrom P450 Systeme aus Bacillus megaterium DSM319 |
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The impact of the clinical CYP11B2 mutation V386A strongly depends on the enzyme's genetic background. |
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In honor of Klaus Ruckpaul. Preface. |
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Inhibition of cytochromes p450: existing and new promising therapeutic targets |
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Insights into the design of a hybrid system between Anabaena ferredoxin-NADP+ reductase and bovine adrenodoxin |
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The interaction domain of the redox protein adrenodoxin is mandatory for binding of the electron acceptor CYP11A1, but is not required for binding of the electron donor adrenodoxin reductase. |
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Intermolecular dynamics studied by paramagnetic tagging. |
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Investigating the roles of T224 and T232 in the oxidation of cinnamaldehyde catalyzed by myxobacterial CYP260B1. |
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Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1). |
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Light-induced reduction of bovine adrenodoxin via the covalently bound ruthenium(II) bipyridyl complex: intramolecular electron transfer and crystal structure |
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Mixed-culture fermentation for enhanced C21-hydroxylation of glucocorticoids |
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Modulation of aldosterone and cortisol synthesis on the molecular level |
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Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors |
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Molecular evolution of a steroid hydroxylating cytochrome P450 using a versatile steroid detection system for screening |
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Molecular recognition between Azotobacter vinelandii rhodanese and a sulfur acceptor protein. |
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Mutations in aldosterone synthase gene of Milan hypertensive rats: phenotypic consequences |
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A new application of the yeast two-hybrid system in protein engineering. |
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New Arabidopsis thaliana cytochrome c partners: a look into the elusive role of cytochrome c in programmed cell death in plants |
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Nongenomic effect of aldosterone on ion transport pathways of red blood cells |
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Novel approach to improve progesterone hydroxylation selectivity by CYP106A2 via rational design of adrenodoxin binding |
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A novel CYP11B2 gene mutation in an Asian family with aldosterone synthase deficiency |
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Novel family members of CYP109 from Sorangium cellulosum So ce56 exhibit characteristic biochemical and biophysical properties. |
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A Novel NADPH-dependent flavoprotein reductase from Bacillus megaterium acts as an efficient cytochrome P450 reductase |
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A novel short chain dehydrogenase from Bacillus megaterium for the conversion of the sesquiterpene nootkatol to (+)-nootkatone |
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A Novel Thermostable Cytochrome P450 from Sequence-Based Metagenomics of Binh Chau Hot Spring as a Promising Catalyst for Testosterone Conversion |
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Optimized chimeragenesis; creating diverse p450 functions. |
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Phenotypic, metabolic, and molecular genetic characterization of six patients with congenital adrenal hyperplasia caused by novel mutations in the CYP11B1 gene. |
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Phosphorylation of bovine adrenodoxin by protein kinase CK2 affects the interaction with its redox partner cytochrome P450scc (CYP11A1). |
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Plasma membrane localization of CYP4Z1 and CYP19A1 and the detection of anti-CYP19A1 autoantibodies in humans |
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Polyamines: naturally occurring small molecule modulators of electrostatic protein-protein interactions |
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The potential of targeting CYP11B. |
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Process development for the production of 15β-hydroxycyproterone acetate using Bacillus megaterium expressing CYP106A2 as whole-cell biocatalyst. |
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Products of gut-microbial tryptophan metabolism inhibit the steroid hormone-synthesizing cytochrome P450 11A1. |
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Protein phosphorylation and intermolecular electron transfer: a joint experimental and computational study of a hormone biosynthesis pathway |
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Proteome analysis ofSchizosaccharomyces pombe by two-dimensional gel electrophoresis and mass spectrometry |
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Purification and functional characterization of human 11beta hydroxylase expressed in Escherichia coli. |
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Raman and infrared spectroscopic evidence for the structural changes of the 2Fe2S cluster and its environment during the interaction of adrenodoxin and adrenodoxin reductase. |
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Redox Partners: Function Modulators of Bacterial P450 Enzymes |
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Regioselective Acetylation of C21 Hydroxysteroids by the Bacterial Chloramphenicol Acetyltransferase I. |
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Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency |
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The role of sulfated steroid hormones in reproductive processes. |
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Scrutiny of electrochemically-driven electrocatalysis of C-19 steroid 1α-hydroxylase (CYP260A1) from Sorangium cellulosum So ce56. |
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Selective oxidation of carotenoid-derived aroma compounds by CYP260B1 and CYP267B1 from Sorangium cellulosum So ce56. |
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Self-association of adrenodoxin studied by using analytical ultracentrifugation |
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Sesquiterpenoids Produced by Combining Two Sesquiterpene Cyclases with Promiscuous Myxobacterial CYP260B1 |
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Shotgun proteomic analysis of the microsomal fraction of eukaryotic cells using a two-dimensional reversed-phase x ion-pair reversed-phase HPLC setup |
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A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56. |
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Some physicochemical properties of flour from germinated sorghum grain |
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Steroid conversion with CYP106A2 - production of pharmaceutically interesting DHEA metabolites |
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Stripping down the mitochondrial cholesterol hydroxylase system, a kinetics study |
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Structural and functional analysis of novel human cytochrome C targets in apoptosis |
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Structural and thermodynamic characterization of the adrenodoxin-like domain of the electron-transfer protein Etp1 from Schizosaccharomyces pombe |
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Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium |
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Structural characterization of CYP260A1 from Sorangium cellulosum to investigate the 1α-hydroxylation of a mineralocorticoid. |
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Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1 |
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Structure-activity profiles of Ab-derived TNF fusion proteins. |
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Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. |
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Substitution of lysine with glutamic acid at position 193 in bovine CYP11A1 significantly affects protein oligomerization and solubility but not enzymatic activity. |
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Substrate Hunting for the Myxobacterial CYP260A1 Revealed New 1α-Hydroxylated Products from C-19 Steroids |
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Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase |
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Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols |
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Theoretical and experimental evaluation of a CYP106A2 low homology model and production of mutants with changed activity and selectivity of hydroxylation |
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ThnY is a ferredoxin reductase-like iron-sulfur flavoprotein that has evolved to function as a regulator of tetralin biodegradation gene expression |
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Towards preparative scale steroid hydroxylation with cytochrome P450 monooxygenase CYP106A2. |
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Transient protein interactions studied by NMR spectroscopy: the case of cytochrome C and adrenodoxin |
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Umsatz von Harzsäuren durch die bakteriellen Cytochrome CYP105A1 und CYP106A2 - strukturelle Grundlagen und potentielle Anwendungen |
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Unfolding and conformational studies on bovine adrenodoxin probed by engineered intrinsic tryptophan fluorescence. |
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Use of high-performance liquid chromatography/electrospray ionization collision-induced dissociation mass spectrometry for structural identification of monohydroxylated progesterones |
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Vertebrate-type and plant-type ferredoxins: crystal structure comparison and electron transfer pathway modelling |
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Vitamin D(3) metabolism in human glioblastoma multiforme: functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol |
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Zwischen Wissenschaft und Politik |
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