Gary R. Mirams
Mirams, Gary, 19..-....
![Sudoc [ABES], France](/viaf/images/flags/SUDOC.png "Sudoc [ABES], France")
VIAF ID: 54166596980117592024 (Personal)
Permalink: http://viaf.org/viaf/54166596980117592024
Preferred Forms
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100 0 _
‡a
Gary R. Mirams
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100 1 _
‡a
Mirams, Gary,
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19..-....
4xx's: Alternate Name Forms (3)
Works
| Title | Sources |
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| Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing. |
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| Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. |
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| Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression. |
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| Cardiac tissue slices: preparation, handling, and successful optical mapping |
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| cellmlmanip and chaste_codegen: automatic CellML to C++ code generation with fixes for singularities and automatically generated Jacobians |
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| Chaste: A test-driven approach to software development for biological modelling |
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| Chaste: an open source C++ library for computational physiology and biology |
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| Chaste: Cancer, Heart and Soft Tissue Environment |
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| Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials |
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| Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century. |
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| A computational study of discrete mechanical tissue models. |
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| Defining vitamin D status using multi-metabolite mathematical modelling: A pregnancy perspective |
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| Early afterdepolarisation tendency as a simulated pro-arrhythmic risk indicator |
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| Evaluation of an in silico cardiac safety assay: using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge |
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| Evaluation of computational modelling as a preclinical proarrhythmic safety assay |
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| Functional Curation: Potential Future Directions for SED-ML |
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| Hierarchical Bayesian inference for ion channel screening dose-response data |
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| High-throughput functional curation of cellular electrophysiology models |
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| Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential |
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| In silico pro-arrhythmia assessment: Can the results of the thorough QT study be predicted? |
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| An integrative computational model for intestinal tissue renewal. |
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| Ion channel model reduction using manifold boundaries |
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| Is it time for in silico simulation of drug cardiac side effects? |
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| A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling |
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| Mathematical modelling and learning of biomedical signals for safety pharmacology |
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| Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts |
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| Models of the cardiac L‐type calcium current: A quantitative review |
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| mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study |
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| A multiple timescale analysis of a mathematical model of the Wnt/beta-catenin signalling pathway |
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| Nonclinical cardiovascular safety of pitolisant: comparing International Conference on Harmonization S7B and Comprehensive in vitro Pro-arrhythmia Assay initiative studies. |
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| Novel approaches to assessing cardiac safety--proceedings of a workshop: regulators, industry and academia discuss the future of in silico cardiac modelling to predict the proarrhythmic safety of drugs |
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| Phenomenological modeling of cell-to-cell and beat-to-beat variability in isolated Guinea Pig ventricular myocytes |
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| Prediction of Thorough QT study results using action potential simulations based on ion channel screens |
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| Recent developments in using mechanistic cardiac modelling for drug safety evaluation |
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| Representation of Multiple Cellular Phenotypes Within Tissue-Level Simulations of Cardiac Electrophysiology |
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| Reproducible model development in the cardiac electrophysiology Web Lab |
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| Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters. |
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| Simulation et apprentissage statistique de signaux biomédicaux pour la pharmacologie de sécurité. |
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| Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk |
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| Ten simple rules for effective computational research |
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| A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt |
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| Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models? |
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| Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment |
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| Voltage protocol design for determining hERG channel kinetics |
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| A web portal for in-silico action potential predictions |
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