Hans Bräuner-Osborne researcher
Bräuner-Osborne, Hans
VIAF ID: 49470455 (Personal)
Permalink: http://viaf.org/viaf/49470455
Preferred Forms
- 200 _ | ‡a Bräuner-Osborne ‡b Hans
- 100 1 _ ‡a Bräuner-Osborne, Hans
- 100 1 _ ‡a Bräuner-Osborne, Hans
-
-
-
- 100 1 _ ‡a Bräuner-Osborne, Hans
- 100 0 _ ‡a Hans Bräuner-Osborne ‡c researcher
4xx's: Alternate Name Forms (10)
Works
Title | Sources |
---|---|
Characterisation of the Family C of G-protein coupled receptors | |
Molecular neuropharmacology : strategies and methods | |
N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization | |
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid | |
No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions. | |
Novel approaches leading towards peptide GPCR de-orphanisation | |
Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites | |
Novel strategies in drug discovery of the calcium-sensing receptor based on biased signaling | |
Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice | |
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW. | |
The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors. | |
Pharmacological characterization of homobaclofen on wild type and mutant GABA(B)1b receptors coexpressed with the GABA(B)2 receptor | |
Pharmacological characterization of human excitatory amino acid transporters EAAT1, EAAT2 and EAAT3 in a fluorescence-based membrane potential assay | |
Pharmacological characterization of ligands at recombinant NMDA receptor subtypes by electrophysiological recordings and intracellular calcium measurements | |
Pharmacological identification of a guanidine-containing β-alanine analogue with low micromolar potency and selectivity for the betaine/GABA transporter 1 (BGT1). | |
Pharmacology and physiological function of the orphan GPRC6A receptor | |
Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells | |
Pharmacology of (S)-homoquisqualic acid and (S)-2-amino-5-phosphonopentanoic acid [(S)-AP5] at cloned metabotropic glutamate receptors | |
Phenylacetic acids and the structurally related non-steroidal anti-inflammatory drug diclofenac bind to specific gamma-hydroxybutyric acid sites in rat brain. | |
Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP | |
Probing intermolecular protein-protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET). | |
Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands | |
Promiscuous seven transmembrane receptors sensing L-α-amino acids | |
Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists | |
The rat GPRC6A: cloning and characterization | |
Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3. | |
Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity | |
Real-time trafficking and signaling of the glucagon-like peptide-1 receptor | |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. | |
Rigid nonproteinogenic cyclic amino acids as ligands for glutamate receptors: trans-tris(homoglutamic) acids | |
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor | |
The role of Arg(78) in the metabotropic glutamate receptor mGlu(1) for agonist binding and selectivity | |
Selective Allosteric Antagonists for the G Protein-Coupled Receptor GPRC6A Based on the 2-Phenylindole Privileged Structure Scaffold | |
Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads | |
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice | |
Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells | |
Structural insight to mutation effects uncover a common allosteric site in class C GPCRs | |
Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359 | |
Structure-activity relationships for negative allosteric mGluR5 modulators | |
Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors | |
Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues | |
Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline. | |
Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid | |
Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists. | |
Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid. | |
Synthesis and Pharmacology of a New AMPA−Kainate Receptor Agonist with Potent Convulsant Activity | |
Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid. | |
Synthesis and receptor binding affinity of new selective GluR5 ligands | |
Synthesis of Conformationally Constrained Glutamic Acid Homologues and Investigation of Their Pharmacological Profiles | |
Synthesis of NovelN1-Substituted Bicyclic Pyrazole Amino Acids and Evaluation of Their Interaction with Glutamate Receptors | |
Synthesis of the calcilytic ligand NPS 2143 | |
Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA. | |
Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology. | |
Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors | |
Transmembrane α-Helix 2 and 7 Are Important for Small Molecule-Mediated Activation of the GLP-1 Receptor | |
Tweaking agonist efficacy at N-methyl-D-aspartate receptors by site-directed mutagenesis. | |
The use of Xenopus oocytes in drug screening | |
Xenopus oocyte electrophysiology in GPCR drug discovery. | |
α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB) |