Kurczab, Rafał (1983- ).
Rafał Kurczab
Kurczab, Rafał
VIAF ID: 48150868217322071010 ( Personal )
Permalink: http://viaf.org/viaf/48150868217322071010
Preferred Forms
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100 1 _ ‡a Kurczab, Rafał
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100 1 _ ‡a Kurczab, Rafał ‡d (1983- ).
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100 0 _
‡a
Rafał Kurczab
4xx's: Alternate Name Forms (8)
Works
| Title | Sources |
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| 11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015. |
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| 2-Aminoimidazole-based antagonists of the 5-HT6 receptor - A new concept in aminergic GPCR ligand design |
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| 2-Phenyl-1 H -pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT 6 Receptor Inverse Agonists with Cognition-Enhancing Activity |
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| 7-Deacetyl-10-alkylthiocolchicine derivatives - new compounds with potent anticancer and fungicidal activity |
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| An Algorithm to Identify Target-Selective Ligands - A Case Study of 5-HT7/5-HT1A Receptor Selectivity |
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| Amino Acid Hot Spots of Halogen Bonding: A Combined Theoretical and Experimental Case Study of the 5-HT7 Receptor |
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| Antifungal, anticancer, and docking studies of colchiceine complexes with monovalent metal cation salts |
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| Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro |
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| Chlorine substituents and linker topology as factors of 5-HT6R activity for novel highly active 1,3,5-triazine derivatives with procognitive properties in vivo |
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| The computer-aided discovery of novel family of the 5-HT6 serotonin receptor ligands among derivatives of 4-benzyl-1,3,5-triazine. |
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| Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT7 receptor agents with antidepressant activity. |
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| Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors |
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| Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents. |
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| The development and validation of a novel virtual screening cascade protocol to identify potential serotonin 5-HT(7)R antagonists. |
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| Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity |
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| A dual-acting 5-HT6 receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties |
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| The Effect of Carboxamide/Sulfonamide Replacement in Arylpiperazinylalkyl Derivatives on Activity to Serotonin and Dopamine Receptors. |
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| The evaluation of QM/MM-driven molecular docking combined with MM/GBSA calculations as a halogen-bond scoring strategy. |
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| An exit beyond the pharmacophore model for 5-HT6R agents - a new strategy to gain dual 5-HT6/5-HT2A action for triazine derivatives with procognitive potential |
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| Fingerprint-based consensus virtual screening towards structurally new 5-HT(6)R ligands. |
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| Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT7 receptor low-basicity agonists, potential neuropathic painkillers |
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| Halogen bonding enhances activity in a series of dual 5-HT6/D2 ligands designed in a hybrid bioisostere generation/virtual screening protocol |
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| How can fluorine directly and indirectly affect the hydrogen bonding in molecular systems? – A case study for monofluoroanilines |
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| Hydrogen Bonds with Fluorine in Ligand–Protein Complexes-the PDB Analysis and Energy Calculations |
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| Imidazopyridine-Based 5-HT 6 Receptor Neutral Antagonists: Impact of N 1 -Benzyl and N 1 -Phenylsulfonyl Fragments on Different Receptor Conformational States |
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| The impact of the halogen bonding on D2 and 5-HT1A/5-HT7 receptor activity of azinesulfonamides of 4-[(2-ethyl)piperidinyl-1-yl]phenylpiperazines with antipsychotic and antidepressant properties. |
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| The influence of negative training set size on machine learning-based virtual screening |
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| The influence of the inactives subset generation on the performance of machine learning methods |
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| Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol |
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| Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol |
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| Mutual Support of Ligand- and Structure-Based Approaches—To What Extent We Can Optimize the Power of Predictive Model? Case Study of Opioid Receptors |
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| N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT(7) receptor selectivity versus multireceptor profile. |
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| Nauka, Technologia i Innowacja |
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| New strategy for receptor-based pharmacophore query construction: a case study for 5-HT₇ receptor ligands |
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| Oddziaływanie dihydroksyacetonu (DHA) zawartego w samoopalaczach z ludzką skórą : badania spektroskopowe i teoretyczne = The influence of dihydroxyacetone (DHA) contained in the self-tanning lotions with human skin : spectroscopic and theoretical studies |
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| ONIOM and FMO-EDA study of metabotropic glutamate receptor 1: Quantum insights into the allosteric binding site |
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| Overcoming undesirable hERG affinity by incorporating fluorine atoms: A case of MAO-B inhibitors derived from 1 H-pyrrolo-[3,2-c]quinolines |
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| Poszukiwanie antagonistów receptora serotoninowego 5-HT7 w grupie pochodnych 5,5-dipodstawionej hydantoiny |
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| Poszukiwanie związków biologicznie aktywnych z wykorzystaniem metod uczenia maszynowego = An application of machine learning methods in the search for biologically active compounds |
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| Projektowanie leków in silico |
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| Pyrazole derivatives : a challenge of modern academic and industrial chemistry |
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| Pyrroloquinoline scaffold-based 5-HT 6 R ligands: Synthesis, quantum chemical and molecular dynamic studies, and influence of nitrogen atom position in the scaffold on affinity |
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| Recognition of repulsive and attractive regions of selected serotonin receptor binding site using FMO-EDA approach |
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| The role of aryl-topology in balancing between selective and dual 5-HTR/5-HT actions of 3,5-substituted hydantoins |
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| Role of Staple Molecules in the Formation of S···S Contact in Thioamides: Experimental Charge Density and Theoretical Studies |
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| Salt Bridge in Ligand–Protein Complexes—Systematic Theoretical and Statistical Investigations |
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| Sci., Technol. Innov. (Tarn.) |
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| Science, Technology and Innovation |
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| The Significance of Halogen Bonding in Ligand-Receptor Interactions: The Lesson Learned from Molecular Dynamic Simulations of the D4 Receptor |
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| -Skatyltryptamines-Dual 5-HTR/DR Ligands with Antipsychotic and Procognitive Potential |
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| Solid-supported synthesis, molecular modeling, and biological activity of long-chain arylpiperazine derivatives with cyclic amino acid amide fragments as 5-HT(7) and 5-HT(1A) receptor ligands |
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| Structural determinants influencing halogen bonding: a case study on azinesulfonamide analogs of aripiprazole as 5-HT1A, 5-HT7, and D2 receptor ligands. |
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| Structure–activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands |
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| Study of the influence of the UV radiation and temperature on the degradation of pharmaceutical formulations containing aspirin using FTIR spectroscopy and chemometrics |
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| Synthesis, 15N NMR spectra and GIAO calculated data of the seven positional isomers of 15N-labeled N,N-dimethylsulfamoylquinoline |
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| Synthesis and anticancer activity evaluation of a quinoline-based 1,2,3-triazoles |
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| Synthesis, molecular docking study, and evaluation of the antiproliferative action of a new group of propargylthio- and propargylselenoquinolines |
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| Theoretical and spectroscopic studies of vibrational spectra of hydrogen bonds in molecular crystal of β-oxalic acid |
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| Theoretical description of hydrogen bonding in oxalic acid dimer and trimer based on the combined extended-transition-state energy decomposition analysis and natural orbitals for chemical valence (ETS-NOCV). |
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| Theoretical Investigations on Interactions of Arylsulphonyl Indazole Derivatives as Potential Ligands of VEGFR2 Kinase |
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| Towards new 5-HT7 antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties. |
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| Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties |
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| Znależć igłę w stogu siana : wirtualny skrining - metody SBVS. |
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