Walter Kolch chercheur
Kolch, Walter
VIAF ID: 43156130956358311751 (Personal)
Permalink: http://viaf.org/viaf/43156130956358311751
Preferred Forms
- 100 1 _ ‡a Kolch, Walter
- 100 1 _ ‡a Kolch, Walter
- 100 0 _ ‡a Walter Kolch ‡c chercheur
4xx's: Alternate Name Forms (4)
Works
Title | Sources |
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Modeling and simulation of intracellular dynamics: choosing an appropriate framework. | |
The molecular make-up of a tumour: proteomics in cancer research | |
Molecular mechanisms of asymmetric RAF dimer activation | |
MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability | |
Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits | |
Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. | |
Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis | |
Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs | |
Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease | |
Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration | |
Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90 | |
Network-based identification of feedback modules that control RhoA activity and cell migration. | |
News | |
Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses | |
On-beads digestion in conjunction with data-dependent mass spectrometry: a shortcut to quantitative and dynamic interaction proteomics | |
On-chip immunoprecipitation for protein purification. | |
Oncogenic B-Raf mutations: crystal clear at last. | |
Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells. | |
Pachinko biology: Gambling on single cells | |
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity | |
Personalized Computational Models as Biomarkers | |
Phosphodiesterase-8A binds to and regulates Raf-1 kinase | |
Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation | |
PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells | |
The PKC targeting protein RACK1 interacts with the Epstein-Barr virus activator protein BZLF1 | |
Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway | |
Preparation of raf-oncogene-specific antiserum with raf protein produced in E. coli. | |
Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells | |
Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling | |
Protein–protein interactions generate hidden feedback and feed-forward loops to trigger bistable switches, oscillations and biphasic dose–responses | |
Proteomic analysis of phosphorylation, oxidation and nitrosylation in signal transduction | |
Proteomics and phosphoproteomics for the mapping of cellular signalling networks | |
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2 | |
Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells | |
Raf-1 and B-Raf promote protein kinase C theta interaction with BAD. | |
Raf family kinases: old dogs have learned new tricks | |
Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability. | |
Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β. | |
RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility | |
RAN GTPase is a RASSF1A effector involved in controlling microtubule organization. | |
Ras/Raf signalling and emerging pharmacotherapeutic targets | |
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein | |
RASSF1A Tumour Suppressor: Target the Network for Effective Cancer Therapy | |
RASSF2 associates with and stabilizes the proapoptotic kinase MST2 | |
The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways. | |
Recommendations for biomarker identification and qualification in clinical proteomics | |
Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis | |
Regulation and role of Raf-1/B-Raf heterodimerization | |
Regulation of human myoblast differentiation by PEBP4 | |
Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis | |
The Renilla luciferase gene as a reference gene for normalization of gene expression in transiently transfected cells | |
The RKIP | |
Robustness and evolvability of the human signaling network | |
ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells | |
Role of inhibitory proteins as modulators of oscillations in NFB signalling. | |
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. | |
The secret life of kinases: functions beyond catalysis | |
Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients | |
Signalling ballet in space and time | |
Signalling mechanisms regulating phenotypic changes in breast cancer cells | |
Silence on the relevant literature and errors in implementation. | |
Snail is a repressor of RKIP transcription in metastatic prostate cancer cells | |
Spatial regulation of ARAF controls the MST2-Hippo pathway. | |
Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development | |
Stabilization of C-RAF:KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF. | |
Studies of perinuclear and nuclear translocation of the Raf-1 protein in rodent fibroblasts | |
Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP | |
Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system | |
Systems biology, 2018: | |
Systems medicine: helping us understand the complexity of disease | |
Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity | |
Targeting MAPK signalling: Prometheus' fire or Pandora's box? | |
Technical, bioinformatical and statistical aspects of liquid chromatography-mass spectrometry (LC-MS) and capillary electrophoresis-mass spectrometry (CE-MS) based clinical proteomics: a critical assessment | |
Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions | |
To be or not to be: a question of B-Raf? | |
The topology design principles that determine the spatiotemporal dynamics of G-protein cascades | |
Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3. | |
Unique reporter-based sensor platforms to monitor signalling in cells | |
Untying the regulation of the Raf-1 kinase | |
Urinary Proteomic Biomarkers in Coronary Artery Disease |