Amy H. Andreotti American biochemist
Andreotti, Amy Hamilton, 1967-
VIAF ID: 36801270 (Personal)
Permalink: http://viaf.org/viaf/36801270
Preferred Forms
4xx's: Alternate Name Forms (1)
Works
| Title | Sources |
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| Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts |
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| Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. |
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| Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurity |
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| Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production |
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| A case study of proline isomerization in cell signaling |
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| Conformational snapshots of Tec kinases during signaling |
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| A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase |
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| Controlling the Activity of the Tec Kinase Itk by Mutation of the Phenylalanine Gatekeeper Residue |
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| Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk. |
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| Defining a two-pronged structural model for PB1 (Phox/Bem1p) domain interaction in plant auxin responses. |
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| Determinants of intra versus intermolecular self-association within the regulatory domains of Rlk and Itk. |
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| Differential impact of BTK active site inhibitors on the conformational state of full-length BTK |
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| Disrupting the intermolecular self-association of Itk enhances T cell signaling |
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| Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases |
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| Electron self-exchange in hemoglobins revealed by deutero-hemin substitution |
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| Identification of an Allosteric Signaling Network within Tec Family Kinases |
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| In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase |
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| Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1. |
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| Ligand specificity modulated by prolyl imide bond Cis/Trans isomerization in the Itk SH2 domain: a quantitative NMR study |
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| The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases |
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| Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases |
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| Mapping the Ca2+ -dependent binding of an invertebrate homolog of protein phosphatase 4 regulatory subunit 2 to the small EF-hand protein, calsensin |
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| Mechanism and functional significance of Itk autophosphorylation |
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| Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response. |
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| Native state proline isomerization: an intrinsic molecular switch |
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| Opening the pore hinges on proline |
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| Part I. The effects of glyycosylation on peptide backbone conformation, 1994: |
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| Positive regulation of Itk PH domain function by soluble IP4 |
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| Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain |
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| Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinase |
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| Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A |
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| Regulatory intramolecular association in a tyrosine kinase of the Tec family |
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| A remote substrate docking mechanism for the tec family tyrosine kinases |
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| Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec. |
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| Role of Reversible Histidine Coordination in Hydroxylamine Reduction by Plant Hemoglobins (Phytoglobins). |
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| Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation |
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| A selective NMR probe to monitor the conformational transition from inactive to active kinase |
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| SH2-dependent autophosphorylation within the Tec family kinase Itk. |
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| The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein |
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| Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO |
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| Solution and micelle-bound structures of tachyplesin I and its active aromatic linear derivatives |
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| Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein |
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| Structural characterization of a proline-driven conformational switch within the Itk SH2 domain |
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| Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures |
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| Substrate recognition of PLCγ1 via a specific docking surface on Itk. |
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| T-cell signaling regulated by the Tec family kinase, Itk. |
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| T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells |
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