Expression profiling in pancreatic cancer research: the initial steps and the road ahead. |
|
The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex |
|
A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth |
|
Gemcitabine Activates Natural Killer Cells to Attenuate Pancreatic Cancer Recurrence. |
|
Genome-wide screen identifies a novel p97/CDC-48-dependent pathway regulating ER-stress-induced gene transcription |
|
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas |
|
GLI1 finds a new role in cancer stem cell biology |
|
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression |
|
Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells |
|
Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion |
|
Hedgehog takes a new "RHOad" to angiogenesis |
|
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6) |
|
Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1. |
|
IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis |
|
Impaired Hedgehog-Gli1 Pathway Activity Underlies the Vascular Phenotype of Polycystic Kidney Disease |
|
Induction of Lysosome-associated Protein Transmembrane 4 Beta via Sulfatase 2 Enhances Autophagic Flux in Liver Cancer Cells |
|
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D. |
|
Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells |
|
It Takes a Village to Overcome KRAS Dependence in Pancreatic Cancer |
|
Key role of Krüppel-like factor proteins in pancreatic cancer and other gastrointestinal neoplasias |
|
KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling |
|
Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young |
|
Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation |
|
LSD1, a double-edged sword, confers dynamic chromatin regulation but commonly promotes aberrant cell growth |
|
Mechanistic insights into self-reinforcing processes driving abnormal histogenesis during the development of pancreatic cancer |
|
Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells. |
|
MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells |
|
Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma |
|
An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation |
|
mTOR-Dependent ARID1A Degradation: A New Twist in the Genetic–Epigenetic Interplay Driving Hepatocellular Carcinoma |
|
New Aspects of the Epigenetics of Pancreatic Carcinogenesis |
|
NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells |
|
NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection |
|
Novel AKT1-GLI3-VMP1 pathway mediates KRAS oncogene-induced autophagy in cancer cells |
|
A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth |
|
A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function |
|
Novel role of VMP1 as modifier of the pancreatic tumor cell response to chemotherapeutic drugs |
|
Novel roles of the unfolded protein response in the control of tumor development and aggressiveness. |
|
Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid |
|
The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation |
|
The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma |
|
Oncogenic transcription factors: cornerstones of inflammation-linked pancreatic carcinogenesis |
|
Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy |
|
Pancreatic cancer research: challenges, opportunities, and recent developments. |
|
Phenotypic correlates and prognostic outcomes of TET2 mutations in myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes: A comprehensive study of 504 adult patients |
|
Pivotal role of Harakiri in the induction and prevention of gentamicin-induced hearing loss |
|
Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα. |
|
A preoperative serum signature of CEA+/CA125+/CA19-9 ≥ 1000 U/mL indicates poor outcome to pancreatectomy for pancreatic cancer |
|
Primers on molecular pathways--the NFAT transcription pathway in pancreatic cancer |
|
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis |
|
Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment. |
|
Response to erythropoiesis-stimulating agents in patients with WHO-defined myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) |
|
Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer |
|
Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis |
|
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function |
|
Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases |
|
Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation |
|
Sequential activation of Snail1 and N-Myc modulates sonic hedgehog-induced transformation of neural cells |
|
Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling |
|
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL |
|
Stromal deactivation by CSF1: a new feature of the aggressive pancreatic cancer microenvironment |
|
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma |
|
Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells |
|
Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1 |
|
The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication |
|
T1385 Adrenomedullin: A Biomarker of Pancreatic Cancer-Associated Diabetes? |
|
Targeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trials |
|
Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk. |
|
Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination |
|
Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion |
|
Targeting tumour microenvironment, a FAKtual challenge in pancreatic cancer |
|
TCR/CD28-stimulated actin dynamics are required for NFAT1-mediated transcription of c-rel leading to CD28 response element activation |
|
TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFβ |
|
Toward personalized TGFβ inhibition for pancreatic cancer |
|
The transcription factor GLI1 cooperates with the chromatin remodeler SMARCA2 to regulate chromatin accessibility at distal DNA regulatory elements |
|
The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner |
|
The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling |
|
Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis |
|
Transcriptional control of gene expression in pancreatic cancer: from sequence-specific transcription factors to nuclear architecture |
|
Transcriptional Induction of Periostin by a Sulfatase 2-TGFβ1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma. |
|
Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB. |
|
Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma. |
|
When developmental signaling pathways go wrong and their impact on pancreatic cancer development |
|
ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells |
|
ZIP4 Promotes Muscle Wasting and Cachexia in Mice with Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells |
|
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and claudin-1 through a ZEB1-Dependent Transcriptional Mechanism. |
|