José V Castell
Castell, J. V.
Castell, José V.
VIAF ID: 305874358 (Personal)
Permalink: http://viaf.org/viaf/305874358
Preferred Forms
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- 100 1 _ ‡a Castell, J. V.
- 100 1 _ ‡a Castell, José V.
- 100 1 0 ‡a Castell, José V.
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- 100 0 _ ‡a José V Castell
4xx's: Alternate Name Forms (6)
Works
Title | Sources |
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In vitro ADME medium/high-throughput screening in drug preclinical development. | |
In vitro alternatives to animal pharmaco-toxicology | |
The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example | |
In vitro methods in pharmaceutical research | |
In vitro studies on DNA-photosensitization by different drug stereoisomers. | |
Influence of platelet lysate on the recovery and metabolic performance of cryopreserved human hepatocytes upon thawing. | |
Influence of preservation solution on the isolation and culture of human hepatocytes from liver grafts. | |
Inhibition of human P450 enzymes by natural extracts used in traditional medicine. | |
Inhibition of monooxygenase activities in human hepatocytes by interferons | |
Interaction between Hhex and SOX13 modulates Wnt/TCF activity | |
Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices. | |
Intracellular glutathione in human hepatocytes incubated with S-adenosyl-L-methionine and GSH-depleting drugs | |
Investigación básica y medicina clínica | |
LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells. | |
Liver cell culture techniques. | |
Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes | |
Long-term storage of peroxidase-labelled immunoglobulins for use in enzyme immunoassay | |
Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes. | |
Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project. | |
Mechanisms of drug photobinding to proteins: photobinding of suprofen to human serum albumin. | |
Mechanisms of photosensitization by drugs: Involvement of tyrosines in the photomodification of proteins mediated by tiaprofenic acid in vitro. | |
Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach. | |
A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury. | |
A microassay for measuring glycogen in 96-well-cultured cells. | |
Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients. | |
MOLECULAR BASIS OF DRUG PHOTOTOXICITY: PHOTOSENSITIZED CELL DAMAGE BY THE MAJOR PHOTOPRODUCT OF TIAPROFENIC ACID | |
Molecular mechanism of diclofenac hepatotoxicity: Association of cell injury with oxidative metabolism and decrease in ATP levels | |
Monitoring of system conditioning after blank injections in untargeted UPLC-MS metabolomic analysis | |
Multiparametric characterization by flow cytometry of flow-sorted subpopulations of a human hepatoma cell line useful for drug research. | |
Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells. | |
New non-woven polyurethane-based biomaterials for the cultivation of hepatocytes: expression of differentiated functions | |
A newin vitroapproach for the simultaneous determination of phase I and phase II enzymatic activities of human hepatocyte preparations | |
Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers | |
Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer. | |
Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes | |
Photobinding of drugs to cells as an indicator of potential photoallergy. | |
PHOTODYNAMIC LIPID PEROXIDATION BY THE PHOTOSENSITIZING NONSTEROIDAL ANTIINFLAMMATORY DRUGS SUPROFEN AND TIAPROFENIC ACID | |
PHOTOLYTIC DEGRADATION OF IBUPROFEN. TOXICITY OF THE ISOLATED PHOTOPRODUCTS ON FIBROBLASTS and ERYTHROCYTES | |
Photophysical characterization and flow cytometry applications of cholylamidofluorescein, a fluorescent bile acid scaffold | |
Photoreactivity of tiaprofenic acid and suprofen using pig skin as an ex vivo model | |
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro testing of the photoproducts of Butibufen and Flurbiprofen | |
Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat | |
Polypodium leucotomos extract: antioxidant activity and disposition | |
Potential hepatoprotective effects of new Cuban natural products in rat hepatocytes culture | |
Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts | |
Potentiation of cocaine hepatotoxicity in human hepatocytes by ethanol | |
Predicting drug-induced cholestasis: preclinical models | |
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations | |
Preliminary results from the Scandinavian multicentre evaluation of in vitro cytotoxicity (MEIC) | |
Primary steps of the photochemical reactions of 2-cyano-10-(3-[dimethylamino, N-oxide]-2-methylpropyl)-5-oxide-phenothiazine, the photoproduct of cyamemazine, a phototoxic neuroleptic: comparison with the sulfoxide | |
Properties of P3 esters of nucleoside triphosphates as substrates for RNA polymerase from Escherichia coli. | |
Quantification of CYP1A1 and 2B1/2 in rat hepatocytes cultured in microwells by immunological methods. | |
Rat hepatocytes cultured on a monkey kidney cell line: Expression of biotransformation and hepatic metabolic activities. | |
Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells | |
Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes | |
Release of Inflammatory Mediators (PGE2, IL-6) by Fenofibric Acid-Photosensitized Human Keratinocytes and Fibroblasts | |
Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes | |
Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease. | |
Role of glucose, insulin, and glucagon in glycogen mobilization in human hepatocytes. | |
Role of hepatocyte nuclear factor 3 gamma in the expression of human CYP2C genes. | |
S-adenosyl-L-methionine reverses the cholestatic effect of ethinylestradiol in rat hepatocytes by increasing its catabolism | |
A score model for the continuous grading of early allograft dysfunction severity. | |
Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes | |
Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes | |
Sequential hepatogenic transdifferentiation of adipose tissue-derived stem cells: relevance of different extracellular signaling molecules, transcription factors involved, and expression of new key marker genes. | |
Silencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells. | |
A simple transcriptomic signature able to predict drug-induced hepatic steatosis. | |
A specific microassay for evaluating hepatic LDH activity in co-cultures of hepatocytes with other cells | |
Steatotic liver: a suitable source for the isolation of hepatic progenitor cells | |
Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: focus on in vitro studies. | |
Synthesis of new, UV-photoactive dansyl derivatives for flow cytometric studies on bile acid uptake. | |
Testing strategies for the safety of nanoparticles used in medical applications | |
Toxic effects of the photoproducts of chlorpromazine on cultured hepatocytes | |
Toxicity of the antitumoral drug datelliptium in hepatic cells: Use of models in vitro for the prediction of toxicity in vivo. | |
Transcriptional regulation of the human hepatic CYP3A4: identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein). | |
Transplantation of hESC-derived hepatocytes protects mice from liver injury | |
Triplet excited fluoroquinolones as mediators for thymine cyclobutane dimer formation in DNA. | |
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells. | |
An update on metabolism studies using human hepatocytes in primary culture | |
The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity. | |
The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes |