Aled Edwards scientifique canadien
Edwards, Aled, 1962-....
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Aled Edwards
VIAF ID: 305460909 (Personal)
Permalink: http://viaf.org/viaf/305460909
Preferred Forms
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100 0 _
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Aled Edwards
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100 0 _
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Aled Edwards
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scientifique canadien
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Edwards, Aled
‡d
1962-
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100 1 _
‡a
Edwards, Aled,
‡d
1962-
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100 1 _
‡a
Edwards, Aled,
‡d
1962-....
4xx's: Alternate Name Forms (7)
5xx's: Related Names (1)
Works
| Title | Sources |
|---|---|
| 10, 2011: |
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| [38] RNA polymerase II transcription in vitro |
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| Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit |
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| In situ proteolysis to generate crystals for structure determination: an update |
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| Interventions for improving understanding and minimising the psychological impact of screening |
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| ISG15, a ubiquitin-like interferon-stimulated gene, promotes hepatitis C virus production in vitro: implications for chronic infection and response to treatment |
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| Leveraging crowdsourcing to facilitate the discovery of new medicines |
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| MAID : an effect size based model for microarray data integration across laboratories and platforms |
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| The Mechanism of Protein Crystal Growth from Lipid Layers |
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| Methyltransferase That Modifies Guanine 966 of the 16 S rRNA: FUNCTIONAL IDENTIFICATION AND TERTIARY STRUCTURE |
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| Molecular characteristics of the epitope in myelin-associated glycoprotein that is recognized by a monoclonal IgM in human neuropathy patients |
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| Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2alpha |
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| New Approaches and Incentives in Drug Development (Conference) (2013 : Washington, D.C.). WorkIng within the current regime, 2013: |
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| New approaches to rewarding pharmaceutical innovation |
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| NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins |
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| NMR structure of the hypothetical protein encoded by the YjbJ gene fromEscherichia coli |
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| Open access chemical and clinical probes to support drug discovery |
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| Open-source science to enable drug discovery |
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| Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins |
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| Personalised risk communication for informed decision making about entering screening programs |
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| Perspective: Science is still too closed |
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| Phosphorylation of Myelin-Associated Glycoprotein In Vivo and In Vitro Occurs Only in the Cytoplasmic Domain of the Large Isoform |
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| Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria |
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| Preclinical target validation using patient-derived cells |
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| The Precompetitive Space: Time to Move the Yardsticks |
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| The promise and peril of chemical probes |
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| A proposal for validation of antibodies. |
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| Proteasome inhibition in vivo promotes survival in a lethal murine model of severe acute respiratory syndrome |
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| Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins |
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| Protein production and purification |
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| A public-private partnership to unlock the untargeted kinome |
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| Refolding out of guanidine hydrochloride is an effective approach for high-throughput structural studies of small proteins |
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| Repeated tertiary fold of RNA polymerase II and implications for DNA binding |
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| Reproducibility: Team up with industry |
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| The RESOLUTE consortium: unlocking SLC transporters for drug discovery |
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| A robust purification strategy to accelerate membrane proteomics |
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| The RPA32 Subunit of Human Replication Protein A Contains a Single-stranded DNA-binding Domain |
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| RPB7, one of two dissociable subunits of yeast RNA polymerase II, is essential for cell viability |
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| Shared decision making and the concept of equipoise: the competences of involving patients in healthcare choices |
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| The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism |
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| Silencing of USP18 potentiates the antiviral activity of interferon against hepatitis C virus infection |
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| Sodium cromoglycate in childhood asthma |
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| Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide |
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| The solution structure of the C-terminal Ig-like domain of the bacteriophage λ tail tube protein |
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| Stopping pandemics before they start: Lessons learned from SARS-CoV-2 |
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| Strategies for structural proteomics of prokaryotes: Quantifying the advantages of studying orthologous proteins and of using both NMR and X-ray crystallography approaches |
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| Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis |
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| Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli |
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| Structural and chemical profiling of the human cytosolic sulfotransferases |
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| Structural and Functional Studies of gpX of Escherichia coli Phage P2 Reveal a Widespread Role for LysM Domains in the Baseplates of Contractile-Tailed Phages. |
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| The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase |
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| The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ |
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| The structural basis of ZMPSTE24-dependent laminopathies |
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| Structural bioinformatics: from protein structure to function |
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| Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members |
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| Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8. |
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| Structural genomics and high throughput structural biology |
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| Structural insights into aldosterone synthase substrate specificity and targeted inhibition |
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| Structural proteomics: a tool for genome annotation |
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| Structure and biochemical functions of SIRT6. |
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| Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum |
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| Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle |
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| Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer. |
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| Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization |
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| Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase |
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| Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states |
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| A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity |
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| Tail tip proteins related to bacteriophage λ gpL coordinate an iron-sulfur cluster |
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| Target 2035: probing the human proteome |
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| Target selection and determination of function in structural genomics |
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| Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma |
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| Too many roads not taken |
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| A trust approach for sharing research reagents. |
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| Unfolding of microarray data. |
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| Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis |
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| What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen? |
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| Yeast Transcript Elongation Factor (TFIIS), Structure and Function |
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| Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum |
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