Christoph Herwig
Herwig, Christoph
Herwig, Christoph 1969-
VIAF ID: 30448150 (Personal)
Permalink: http://viaf.org/viaf/30448150
Preferred Forms
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100 0 _ ‡a Christoph Herwig
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100 1 _ ‡a Herwig, Christoph
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100 1 _ ‡a Herwig, Christoph ‡d 1969-
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100 1 _ ‡a Herwig, Christoph ‡d 1969-
4xx's: Alternate Name Forms (2)
5xx's: Related Names (1)
Works
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Bioprocess development workflow: Transferable physiological knowledge instead of technological correlations |
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Bioprocess Engineering Aspects of Sustainable Polyhydroxyalkanoate Production in Cyanobacteria |
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Bioprocess monitoring: minimizing sample matrix effects for total protein quantification with bicinchoninic acid assay |
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Combining light microscopy, dielectric spectroscopy, MALDI intact cell mass spectrometry, FTIR spectromicroscopy and multivariate data mining for morphological and physiological bioprocess characterization of filamentous organisms |
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Combining mechanistic and data-driven approaches to gain process knowledge on the control of the metabolic shift to lactate uptake in a fed-batch CHO process. |
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Comparison of Fiber Optic and Conduit Attenuated Total Reflection (ATR) Fourier Transform Infrared (FT-IR) Setup for In-Line Fermentation Monitoring. |
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A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cells |
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Determination of carbohydrates present in Saccharomyces cerevisiae using mid-infrared spectroscopy and partial least squares regression. |
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Digital twins, 2021: |
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A dynamic method for the investigation of induced state metabolic capacities as a function of temperature |
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Dynamics in bioprocess development for Pichia pastoris. |
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Essential prerequisites for successful bioprocess development of biological CH4 production from CO2 and H2. |
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Examining the freezing process of an intermediate bulk containing an industrially relevant protein. |
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A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains. |
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Fed-Batch Production of Bacterial Ghosts Using Dielectric Spectroscopy for Dynamic Process Control. |
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The filamentous fungal pellet-relationship between morphology and productivity. |
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Generation of PHB from Spent Sulfite Liquor Using Halophilic Microorganisms |
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High throughput inclusion body sizing: Nano particle tracking analysis. |
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How to Determine Interdependencies of Glucose and Lactose Uptake Rates for Heterologous Protein Production with E. coli |
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Identification of lipophilic bioproduct portfolio from bioreactor samples of extreme halophilic archaea with HPLC-MS/MS. |
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Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3). |
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The impact of pH inhomogeneities on CHO cell physiology and fed-batch process performance - two-compartment scale-down modelling and intracellular pH excursion. |
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Inclusion Body Bead Size in Controlled by Physiological Feeding |
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Information Processing: Rate-Based Investigation of Cell Physiological Changes along Design Space Development. |
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Intact cell mass spectrometry as a progress tracking tool for batch and fed-batch fermentation processes |
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An Integrated Downstream Process Development Strategy along QbD Principles. |
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Investigation of the interactions of critical scale-up parameters (pH, pO2 and pCO2) on CHO batch performance and critical quality attributes |
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Investigation of the physiological response to oxygen limited process conditions of Pichia pastoris Mut(+) strain using a two-compartment scale-down system |
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Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris. |
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Know-how and know-why in biochemical engineering |
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Knowledge management in the QbD paradigm: manufacturing of biotech therapeutics. |
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Mechanistic platform knowledge of concomitant sugar uptake in Escherichia coli BL21(DE3) strains |
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Metabolic Control in Mammalian Fed-Batch Cell Cultures for Reduced Lactic Acid Accumulation and Improved Process Robustness |
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Method for assessing the impact of emission gasses on physiology and productivity in biological methanogenesis |
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Microbials for the production of monoclonal antibodies and antibody fragments. |
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Model-based analysis on the relationship of signal quality to real-time extraction of information in bioprocesses. |
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Model-Based Methods in the Biopharmaceutical Process Lifecycle |
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Morphological analysis of the filamentous fungus Penicillium chrysogenum using flow cytometry-the fast alternative to microscopic image analysis |
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Multi-analyte quantification in bioprocesses by Fourier-transform-infrared spectroscopy by partial least squares regression and multivariate curve resolution |
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Multi-parameter flow cytometry as a process analytical technology (PAT) approach for the assessment of bacterial ghost production. |
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Multivariate Monitoring Workflow for Formulation, Fill and Finish Processes |
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A novel cytosolic NADH:quinone oxidoreductase from Methanothermobacter marburgensis. |
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A novel method for fast and statistically verified morphological characterization of filamentous fungi. |
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A novel method to recover inclusion body protein from recombinant E. coli fed-batch processes based on phage ΦX174-derived lysis protein E. |
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A novel toolbox for E. coli lysis monitoring |
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Observability analysis of biochemical process models as a valuable tool for the development of mechanistic soft sensors. |
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On-line exploitation tools for the quantitative analysis of metabolic regulations in microbial cultures |
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Optimization of sample preparation for intact cell mass spectrometry (matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry) of endophytic Xylaria |
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Photosynthetic poly-β-hydroxybutyrate accumulation in unicellular cyanobacterium Synechocystis sp. PCC 6714. |
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Physiological capacities decline during induced bioprocesses leading to substrate accumulation. |
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Physiological description of multivariate interdependencies between process parameters, morphology and physiology during fed-batch penicillin production |
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Prediction of filamentous process performance attributes by CSL quality assessment using mid-infrared spectroscopy and chemometrics. |
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Predictive Monitoring of Shake Flask Cultures with Online Estimated Growth Models |
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Production and purification of the multifunctional enzyme horseradish peroxidase. |
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Production of Active Recombinant Hyaluronidase Inclusion Bodies from Apis mellifera in E. coli Bl21(DE3) and characterization by FT-IR Spectroscopy |
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Production strategies for active heme-containing peroxidases from E. coli inclusion bodies - a review. |
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Propagation of measurement accuracy to biomass soft-sensor estimation and control quality. |
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Purification of a recombinant plant peroxidase produced in Pichia pastoris by a simple 2-step strategy |
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Quantification of cell lysis during CHO bioprocesses: Impact on cell count, growth kinetics and productivity. |
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Quantitative analysis of the regulation scheme of invertase expression in Saccharomyces cerevisiae. |
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Quantitative comparison of dynamic physiological feeding profiles for recombinant protein production with Pichia pastoris |
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Quantitative CPP Evaluation from Risk Assessment Using Integrated Process Modeling |
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Radial line-scans as representative sampling strategy in dried-droplet laser ablation of liquid samples deposited on pre-cut filter paper disks |
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A rapid method for the differentiation of yeast cells grown under carbon and nitrogen-limited conditions by means of partial least squares discriminant analysis employing infrared micro-spectroscopic data of entire yeast cells |
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Reagent-free monitoring of multiple clinically relevant parameters in human blood plasma using a mid-infrared quantum cascade laser based sensor system. |
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Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes. |
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Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway |
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Risk-based Process Development of Biosimilars as Part of the Quality by Design Paradigm. |
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A robust feeding strategy to maintain set-point glucose in mammalian fed-batch cultures when input parameters have a large error. |
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Role of Knowledge Management in Development and Lifecycle Management of Biopharmaceuticals |
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Science-based bioprocess design for filamentous fungi. |
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Soft Sensor-Based Monitoring and Efficient Control Strategies of Biomass Concentration for Continuous Cultures of Haloferax mediterranei and Their Application to an Industrial Production Chain |
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Soft sensor for monitoring biomass subpopulations in mammalian cell culture processes |
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Stoichiometric and kinetic analysis of extreme halophilic Archaea on various substrates in a corrosion resistant bioreactor. |
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Substrate oscillations boost recombinant protein release from Escherichia coli |
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Switching industrial production processes from complex to defined media: method development and case study using the example of Penicillium chrysogenum. |
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Teaching an old pET new tricks: tuning of inclusion body formation and properties by a mixed feed system in E. coli |
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Toward a Noninvasive, Label-Free Screening Method for Determining Spore Inoculum Quality of Penicillium chrysogenum Using Raman Spectroscopy. |
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Tunable recombinant protein expression with E. coli in a mixed-feed environment. |
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Ultrasound-enhanced attenuated total reflection mid-infrared spectroscopy in-line probe: acquisition of cell spectra in a bioreactor |
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Universal Capacitance Model for Real-Time Biomass in Cell Culture. |
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Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1. |
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Workflow for multi-analyte bioprocess monitoring demonstrated on inline NIR spectroscopy of P. chrysogenum fermentation. |
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Workflow for Target-Oriented Parametrization of an Enhanced Mechanistic Cell Culture Model. |
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