Mark A. Lemmon David A. Sackler Professor of Pharmacology at Yale University where he co-directs the Cancer Biology Institute with Joseph Schlessinger
Lemmon, M. A.
Lemmon, Mark A.
VIAF ID: 296523722 (Personal)
Permalink: http://viaf.org/viaf/296523722
Preferred Forms
4xx's: Alternate Name Forms (3)
Works
| Title | Sources |
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| Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices |
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| The glycophorin A transmembrane domain dimer: Sequence-specific propensity for a right-handed supercoil of helixes |
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| Helix-helix interactions inside lipid bilayers |
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| Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation |
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| Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast |
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| Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity |
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| Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. |
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| Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB |
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| Insulin and EGF receptor family members share parallel activation mechanisms |
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| The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain |
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| Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids |
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| Kit receptor dimerization is driven by bivalent binding of stem cell factor |
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| Ligand-induced structural transitions in ErbB receptor extracellular domains |
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| Ligand regulation of a constitutively dimeric EGF receptor |
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| Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study |
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| Looking lively: emerging principles of pseudokinase signaling |
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| Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis |
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| Mechanism of activation and inhibition of the HER4/ErbB4 kinase |
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| Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions |
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| Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases |
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| Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic |
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| N-terminal domains elicit formation of functional Pmel17 amyloid fibrils |
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| Neuregulin Signaling Is a Mechanism of Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma |
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| Non-acylated Wnts Can Promote Signaling |
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| Normalization of nomenclature for peptide motifs as ligands of modular protein domains |
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| Occupy EGFR. |
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| On the nature of low- and high-affinity EGF receptors on living cells |
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| An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors |
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| Overcoming resistance to HER2 inhibitors through state-specific kinase binding |
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| The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate. |
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| Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion |
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| Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions |
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| Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation |
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| Phosphatidylserine binding directly regulates TIM-3 function |
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| The Pleckstrin Homology Domains of Dynamin Isoforms Require Oligomerization for High Affinity Phosphoinositide Binding |
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| Pleckstrin homology domains: two halves make a hole? |
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| A possible effector role for the pleckstrin homology |
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| Protein kinase C regulation: C1 meets C-tail. |
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| Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins |
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| Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? |
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| Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. |
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| Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae. |
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| The role of the pleckstrin homology domain in membrane targeting and activation of phospholipase Cbeta(1). |
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| ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes |
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| Scratching the surface with the PH domain. |
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| Signaling by receptor tyrosine kinases, 2013: |
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| A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein |
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| The single transmembrane domains of ErbB receptors self-associate in cell membranes |
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| Smoothening out the patches |
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| Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy |
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| Specific role for the PH domain of dynamin-1 in the regulation of rapid endocytosis in adrenal chromaffin cells |
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| Specificity and promiscuity in membrane helix interactions |
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| Specificity of the myotubularin family of phosphatidylinositol-3-phosphatase is determined by the PH/GRAM domain |
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| Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond |
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| Structural basis for ligand reception by anaplastic lymphoma kinase |
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| Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain |
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| Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor |
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| Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel |
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| A structure-based model for ligand binding and dimerization of EGF receptors |
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| Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling |
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| Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors |
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| The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function |
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| Thermodynamic studies of tyrosyl-phosphopeptide binding to the SH2 domain of p56lck |
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| TIPE3 is the transfer protein of lipid second messengers that promote cancer |
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| Transmembrane signaling by receptor oligomerization |
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