Advancements in molecular prognostics and diagnostics of pediatric myelodysplastic syndrome and juvenile myelomonocytic leukemia / Silvia Bresolin ; direttore della Scuola: Giuseppe Basso ; coordinatore d'indirizzo: Giuseppe Basso ; supervisore: Geertruy Te Kronnie |
|
Aerobic glycolysis tunes YAP/TAZ transcriptional activity |
|
Annexin 2A sustains glioblastoma cell dissemination and proliferation |
|
Array-based comparative genomic hybridization analysis reveals chromosomal copy number aberrations associated with clinical outcome in canine diffuse large B-cell lymphoma |
|
CREB engages C/EBPδ to initiate leukemogenesis. |
|
Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis |
|
Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia. |
|
Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma |
|
ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype. |
|
Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways |
|
Gene Expression–Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia |
|
Gene expression signatures of pediatric myelodysplastic syndromes are associated with risk of evolution into acute myeloid leukemia. |
|
Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia. |
|
GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia. |
|
Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ. |
|
The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories. |
|
LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19. |
|
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia. |
|
Mesenchymal stem cells from Shwachman-Diamond syndrome patients display normal functions and do not contribute to hematological defects. |
|
MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation |
|
MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment |
|
MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia |
|
MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study |
|
Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group |
|
A novel germline variant in PIK3R1 results in SHORT syndrome associated with TAL/LMO T-cell Acute Lymphoblastic Leukemia |
|
NPM-ALK expression levels identify two distinct subtypes of paediatric anaplastic large cell lymphoma. |
|
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
|
Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL. |
|
Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins |
|
Proteomic Alterations in Response to Hypoxia Inducible Factor 2α in Normoxic Neuroblastoma Cells |
|
Refinement of IKZF1 status in pediatric Philadelphia-positive acute lymphoblastic leukemia. |
|
Role of TAZ as mediator of Wnt signaling |
|
Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in Juvenile myelomonocytic leukemia patients. |
|
Validation of flow cytometric phospho-STAT5 as a diagnostic tool for juvenile myelomonocytic leukemia |
|
Wnt activation promotes neuronal differentiation of glioblastoma |
|
YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response |
|
ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia. |
|