Robin Franklin British stem cell biologist
Franklin, Robin J.M.
VIAF ID: 267597097 (Personal)
Permalink: http://viaf.org/viaf/267597097
Preferred Forms
- 100 1 _ ‡a Franklin, Robin J. M.
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- 100 1 _ ‡a Franklin, Robin J.M.
- 100 1 _ ‡a Franklin, Robin J.M.
- 100 0 _ ‡a Robin Franklin ‡c British stem cell biologist
4xx's: Alternate Name Forms (3)
Works
Title | Sources |
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Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain | |
Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination. | |
Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity? | |
Do your glial cells make you clever? | |
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS | |
Effects of pre- versus post-anaesthetic buprenorphine on propofol-anaesthetized rats. | |
Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen. | |
Efficient Remyelination Requires DNA Methylation | |
The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination | |
Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) via β1 Integrin. | |
The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelination | |
Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS. | |
FGF but not EGF induces phosphorylation of the cAMP response element binding protein in olfactory mucosa-derived cell cultures. | |
Fibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions. | |
Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency | |
Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage | |
Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. | |
Glia Disease and Repair-Remyelination | |
Glial cell transplants that are subsequently rejected can be used to influence regeneration of glial cell environments in the CNS | |
Hereditary ataxia, myokymia and neuromyotonia in Jack Russell terriers | |
High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology. | |
Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. | |
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis. | |
Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes | |
Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells | |
The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche. | |
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells. | |
LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination. | |
A map of transcriptional heterogeneity and regulatory variation in human microglia | |
Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy. | |
Mechanical environment modulates biological properties of oligodendrocyte progenitor cells. | |
Mechanisms of CNS remyelination--the key to therapeutic advances. | |
Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. | |
Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination. | |
MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter. | |
Mutations in genes causing human familial isolated hyperparathyroidism do not account for hyperparathyroidism in Keeshond dogs | |
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling | |
Myelin regeneration: a recapitulation of development? | |
Myelin repair and neuroprotection in multiple sclerosis, c2013: | |
Myokymia and neuromyotonia in veterinary medicine: a comparison with peripheral nerve hyperexcitability syndrome in humans. | |
Nasal and frontal sinus mucosa of the adult dog contain numerous olfactory sensory neurons and ensheathing glia. | |
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system. | |
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes | |
Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis | |
Neuronal vulnerability and multilineage diversity in multiple sclerosis | |
Neuroscience. The mysteries of myelin unwrapped. | |
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. | |
Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity | |
Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS | |
Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination | |
Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis. | |
The phagocytic capacity of neurones | |
Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes. | |
Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination. | |
Reconstruction of the glia limitans by sub-arachnoid transplantation of astrocyte-enriched cultures | |
Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease. | |
Regenerating CNS myelin - from mechanisms to experimental medicines. | |
Regenerative Medicines for Remyelination: From Aspiration to Reality | |
Remyelination - An effective means of neuroprotection. | |
Response of olfactory ensheathing cells to the degeneration and regeneration of the peripheral olfactory system and the involvement of the neuregulins | |
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination | |
Retinoid X receptors as a potential avenue for regenerative medicine in multiple sclerosis | |
Schwann cell precursors: a favourable cell for myelin repair in the Central Nervous System. | |
Schwann cell remyelination is restricted to astrocyte-deficient areas after transplantation into demyelinated adult rat brain | |
Schwann cells transplanted into normal and X-irradiated adult white matter do not migrate extensively and show poor long-term survival. | |
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes | |
Special issue on stem cells: "the end of the beginning". | |
Stem cell treatments and multiple sclerosis | |
Stem cells, progenitors and myelin repair. | |
Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice. | |
Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS | |
Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors | |
The translational biology of remyelination: past, present, and future | |
Type 1 astrocytes fail to inhibit Schwann cell remyelination of CNS axons in the absence of cells of the O-2A lineage. | |
Tyrosine kinases: maiming myelin in leprosy | |
Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin | |
Up-regulation of oligodendrocyte precursor cell alphaV integrin and its extracellular ligands during central nervous system remyelination. | |
The VF rat with abnormal myelinogenesis has a mutation in Dopey1. | |
Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation | |
What roles do growth factors play in CNS remyelination? |