Edwin R Chapman
Chapman, Edwin, Ph. D.
VIAF ID: 259815456 (Personal)
Permalink: http://viaf.org/viaf/259815456
Preferred Forms
-
100 1 _
‡a
Chapman, Edwin,
‡c
Ph. D.
-
100 0 _
‡a
Edwin R Chapman
4xx's: Alternate Name Forms (3)
Works
| Title | Sources |
|---|---|
| Ca2+ sensors for exocytosis, 2012: |
|
| Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission |
|
| CAPS Acts at a Prefusion Step in Dense-Core Vesicle Exocytosis as a PIP2 Binding Protein |
|
| Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells |
|
| Delineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagmin |
|
| Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. |
|
| Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. |
|
| Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm |
|
| Different states of synaptotagmin regulate evoked versus spontaneous release |
|
| Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granules |
|
| Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity |
|
| Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release. |
|
| Doc2-mediated superpriming supports synaptic augmentation |
|
| Dual interaction of synaptotagmin with mu2- and alpha-adaptin facilitates clathrin-coated pit nucleation |
|
| Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties. |
|
| ENaC subunit-subunit interactions and inhibition by syntaxin 1A |
|
| ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously. |
|
| Excitatory and Inhibitory Neurons Utilize Different Ca2+ Sensors and Sources to Regulate Spontaneous Release. |
|
| Exocytotic fusion pores are composed of both lipids and proteins |
|
| Fluorescence energy transfer analysis of calmodulin-peptide complexes |
|
| Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1. |
|
| Functional Domains of Neuromodulin and the Interaction of Calmodulin with Target Peptides |
|
| Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions. |
|
| G.I. Joe |
|
| Glycosylation is dispensable for sorting of synaptotagmin 1 but is critical for targeting of SV2 and synaptophysin to recycling synaptic vesicles |
|
| Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells |
|
| Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation |
|
| Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure |
|
| Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons. |
|
| The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. |
|
| Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission |
|
| Lipid-anchored Synaptobrevin Provides Little or No Support for Exocytosis or Liposome Fusion. |
|
| Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy |
|
| Lipid mixing and content release in single-vesicle, SNARE-driven fusion assay with 1-5 ms resolution |
|
| MARCKS-ED peptide as a curvature and lipid sensor |
|
| Membrane-embedded synaptotagmin penetrates cis or trans target membranes and clusters via a novel mechanism |
|
| Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo |
|
| Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder |
|
| Molecular regulation of membrane resealing in 3T3 fibroblasts. |
|
| Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles |
|
| Mutations in the effector binding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a nonadditive manner |
|
| Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission |
|
| The neuronal exocytotic fusion machine: some new developments. |
|
| Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion |
|
| Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation |
|
| Permeation of styryl dyes through nanometer-scale pores in membranes |
|
| Phosphatidylinositol 4,5-bisphosphate drives Ca2+-independent membrane penetration by the tandem C2 domain proteins synaptotagmin-1 and Doc2β |
|
| Poisoning by botulinum neurotoxin A does not inhibit formation or disassembly of the synaptosomal fusion complex. |
|
| Postsynaptic Neuroligin1 regulates presynaptic maturation |
|
| Productive hemifusion intermediates in fast vesicle fusion driven by neuronal SNAREs. |
|
| Programmable Nanodisc Patterning by DNA Origami |
|
| Pulling force generated by interacting SNAREs facilitates membrane hemifusion. |
|
| Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals |
|
| Rat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusion |
|
| Receptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly. |
|
| Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells |
|
| Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores |
|
| Retargeted clostridial neurotoxins as novel agents for treating chronic diseases. |
|
| Sar1 GTPase Activity Is Regulated by Membrane Curvature. |
|
| Sex-specific regulation of follicle-stimulating hormone secretion by synaptotagmin 9. |
|
| Single molecule mechanical probing of the SNARE protein interactions |
|
| SNAP-23 functions in docking/fusion of granules at low Ca2+. |
|
| SNARE-complex disassembly by NSF follows synaptic-vesicle fusion |
|
| Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR |
|
| Structural basis of cell surface receptor recognition by botulinum neurotoxin B |
|
| Structural elements that underlie Doc2β function during asynchronous synaptic transmission. |
|
| Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin |
|
| Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways |
|
| Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment |
|
| Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells. |
|
| Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+. |
|
| The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion. |
|
| Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis |
|
| Synaptotagmin-Ca2+ triggers two sequential steps in regulated exocytosis in rat PC12 cells: fusion pore opening and fusion pore dilation |
|
| Synaptotagmin isoforms confer distinct activation kinetics and dynamics to chromaffin cell granules. |
|
| Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion |
|
| Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release |
|
| Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion |
|
| Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells |
|
| The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis. |
|
| Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons |
|
| Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis. |
|
| Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity. |
|
| Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles. |
|
| Univ. of Wisconsin-Madison, Dept. of Neuroscience Web site, viewed July 20, 2012: |
|
| Visualization of synaptotagmin I oligomers assembled onto lipid monolayers. |
|
