Accumulation of drugs in tubular cells of the kidney |
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Evaluating Human Intestinal Cell Lines for Studying Dietary Protein Absorption. |
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Extrahepatic metabolism of ibrutinib |
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Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds |
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Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia |
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Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus. |
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Fluorescently Labeled Cyclodextrin Derivatives as Exogenous Markers for Real-Time Transcutaneous Measurement of Renal Function. |
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From portable dialysis to a bioengineered kidney. |
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The functional implications of common genetic variation in CYP3A5 and ABCB1 in human proximal tubule cells. |
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Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review |
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Heterogeneous transport of digitalis-like compounds by P-glycoprotein in vesicular and cellular assays. |
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Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations |
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Humans are animals, but are animals human enough? A systematic review and meta-analysis on interspecies differences in renal drug clearance |
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Humoral signalling compounds in remote ischaemic preconditioning of the kidney, a role for the opioid receptor. |
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Hydrogel-based cell therapies for kidney regeneration: current trends in biofabrication and in vivo repair. |
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The importance of breast cancer resistance protein to the kidneys excretory function and chemotherapeutic resistance |
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In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes |
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In vitro systems to study nephropharmacology: 2D versus 3D models |
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Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling. |
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The Influence of Dietary Protein Intake on Mammalian Tryptophan and Phenolic Metabolites. |
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Inhibition of Nrf2 alters cell stress induced by chronic iron exposure in human proximal tubular epithelial cells |
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Innovations in approaches to remove uraemic toxins |
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Insights into the role of bone marrow-derived stem cells in renal repair. |
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Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4. |
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Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules. |
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An introduction to the pharmacology of kidney regeneration |
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The kidney and uremic toxin removal: glomerulus or tubule? |
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Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening. |
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Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones. |
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Low-titre inhibitors, undetectable by the Nijmegen assay, reduce factor VIII half-life after immune tolerance induction. |
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Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model. |
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Modulatory effects of hormones, drugs, and toxic events on renal organic anion transport |
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A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue. |
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Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules |
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New insights into the effects of biomaterial chemistry and topography on the morphology of kidney epithelial cells |
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Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia. |
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Novel Dietary Proteins Selectively Affect Intestinal Health In Vitro after Clostridium difficile-Secreted Toxin A Exposure |
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Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells |
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P-glycoprotein-deficient mice have proximal tubule dysfunction but are protected against ischemic renal injury |
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Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers |
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Phase I/II trial of a combination of anti-CD3/CD7 immunotoxins for steroid-refractory acute graft-versus-host disease |
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The potential of alkaline phosphatase as a treatment for sepsis-associated acute kidney injury |
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Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study |
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Prophylactic effect of recombinant factor VIIa in factor VII deficient patients. |
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A proteome comparison between human fetal and mature renal extracellular matrix identifies EMILIN1 as a regulator of renal epithelial cell adhesion |
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Proteomic profiling in incubation medium of mouse, rat and human precision-cut liver slices for biomarker detection regarding acute drug-induced liver injury. |
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Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology |
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Quantification of cystine in human renal proximal tubule cells using liquid chromatography-tandem mass spectrometry. |
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Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease |
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A Randomized Trial of Distal Diuretics versus Dietary Sodium Restriction for Hypertension in Chronic Kidney Disease |
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Regulatory pathways for ATP-binding cassette transport proteins in kidney proximal tubules |
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Remote ischaemic preconditioning by brief hind limb ischaemia protects against renal ischaemia-reperfusion injury: the role of adenosine |
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Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion |
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Renal Epithelial Monolayer Formation on Monomeric and Polymeric Catechol Functionalized Supramolecular Biomaterials |
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Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus. |
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Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury. |
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Renal Tubular- and Vascular Basement Membranes and their Mimicry in Engineering Vascularized Kidney Tubules |
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Rhodamine 123 accumulates extensively in the isolated perfused rat kidney and is secreted by the organic cation system |
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The role of ATP binding cassette transporters in tissue defense and organ regeneration. |
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Role of p-glycoprotein expression and function in cystinotic renal proximal tubular cells |
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Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions |
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Saturable accumulation and diuretic activity of hydrochlorothiazide in the isolated perfused rat kidney |
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Screening for the role of transporters in hepatic and renal drug handling |
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Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip |
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Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes |
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Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule. |
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Short-term beneficial effects of methylene blue on kidney damage in septic shock patients. |
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Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity. |
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Spinach and Chive for Kidney Tubule Engineering: the Limitations of Decellularized Plant Scaffolds and Vasculature |
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Subunit-specific incorporation efficiency and kinetics in mitochondrial complex I homeostasis |
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Switch in FGFR3 and -4 expression profile during human renal development may account for transient hypercalcemia in patients with Sotos syndrome due to 5q35 microdeletions |
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Therapeutic implications of renal anionic drug transporters. |
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Towards a bioengineered kidney: recellularization strategies for decellularized native kidney scaffolds. |
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Transport of a fluorescent cAMP analog in teleost proximal tubules |
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Tubular reabsorption and local production of urine hepcidin-25. |
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Tubuloids derived from human adult kidney and urine for personalized disease modeling |
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Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury. |
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Upscaling of a living membrane for bioartificial kidney device. |
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Uremic Solutes in Chronic Kidney Disease and Their Role in Progression |
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Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration. |
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Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations. |
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