A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11 |
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Analysis of the function of Notchless in the mouse and of its implication in the Notch signaling pathway. |
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The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo |
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Beyond 'knock-out' mice: new perspectives for the programmed modification of the mammalian genome. |
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Caractérisation de la différenciation de l'endoderme primitif : Coopération entre la voie de signalisation RTK-FGF et le facteur de transcription Gata 6 |
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Caractérisation de l'effet de mutations MODY sur la fonction de bookmarking de HNF1beta |
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CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha. |
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CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium |
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Cell cycle regulation during early mouse embryogenesis. |
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Cellules souches pluripotentes induites de lapin : caractérisation moléculaire et fonctionnelle des états naïf et amorcé |
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Characterisation of the expression of factors potentially involved in epiblast specification in the preimplantation mouse embryo. |
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Compartmentalization of lambda subtype expression in the B cell repertoire of mice with a disrupted or normal C kappa gene segment |
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Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium |
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Crosstalks between ribosome biogenesis and stem cell regulation : study of the role of Notchless in hematopoietic stem cells homeostasis in adult mouse. |
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The crucial roles played by HNF1β during kidney development |
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CTCF confers local nucleosome resiliency after DNA replication and during mitosis |
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Déchiffrer le continuum de pluripotence dans l'embryon pré-implantatoire de lapin |
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Deciphering the molecular network controlling pig pluripotency. |
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Developmental expression of H-2K major histocompatibility complex class I transgenes requires the presence of proximal introns. |
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Direct reprogramming of somatic cells into human induced naive pluripotent stem cells, a novel model of preimplantation epiblast cells |
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Disruption of murine Hexa gene leads to enzymatic deficiency and to neuronal lysosomal storage, similar to that observed in Tay-Sachs disease |
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Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain |
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Etude de l'implication du gène Omcg1 dans le maintien de l'intégrité du génome |
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Étude du rôle de la méthylation de l'ADN dans l'émergence des identités cellulaires au cours de l'embryogenèse. |
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Functional analysis of Ovum mutant candidate gene 1 : from early mouse development to cell cycle contyrol. |
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Functional characterization of the imprinted Liz/Zdbf2 locus in mice : from the early embryo to adult physiology |
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ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation |
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Identification of candidate genes for Blackfan-Diamond anemia and phenotypic characterization. |
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Implication de la biogenèse des ribosomes dans la régulation des cellules souches : étude du gène Notchless dans l'homéostasie des cellules souches hématopoïétiques chez la souris adulte |
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In vivo exploration of the impact of ribosome biogenesis alterations on intestinal homeostasis and tumorigenesis in the adult mouse |
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[Inhibition of endocytic recycling by Rififylin] |
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Integration of H-2Z1, a somatosensory cortex-expressed transgene, interferes with the expression of the Satb1 and Tbc1d5 flanking genes and affects the differentiation of a subset of cortical interneurons. |
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lacZ and ubiquitously expressed genes: should divorce be pronounced? |
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lacZ sequences prevent regulated expression of housekeeping genes. |
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L'échec de l'homéostasie intestinale normale sous l'influence de signaux de paracrine dérivés de cellules tumorales |
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L'hétérochromatine comme marqueur de l'état de pluripotence : comparaison de modèles in vivo (embryons de mammifères) et in vitro (cellules souches) |
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Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network |
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MODY mutations specifically affect the mitotic chromatin localization of HNF1beta. |
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Molecular analysis of consequences of activation of Wnt/b-catenin pathway : description of autophagy during intestinal carcinogenesis. |
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Molecular heterogeneity of progenitors and radial migration in the developing cerebral cortex revealed by transgene expression. |
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A multiscale model of early cell lineage specification including cell division |
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The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells |
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Naive and primed murine pluripotent stem cells have distinct miRNA expression profiles |
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[A new era in rat genetics] |
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Nobel Prize 2007 for Medicine to Mario Capecchi, Martin Evans and Oliver Smithies: the mutant mice to order |
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Nonpermissiveness for mouse embryonic stem (ES) cell derivation circumvented by a single backcross to 129/Sv strain: establishment of ES cell lines bearing the Omd conditional lethal mutation. |
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[Notch signalling pathway and early mammalian embryogenesis] |
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Notchless defines a stage-specific requirement for ribosome biogenesis during lineage progression in adult skeletal myogenesis |
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Notchless is required for axial skeleton formation in mice |
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Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation |
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Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite. |
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Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote. |
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PDGF Signaling in Primitive Endoderm Cell Survival Is Mediated by PI3K-mTOR Through p53-Independent Mechanism |
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Physiopathological study of Crouzon syndrome with acanthosis nigricans related to FGFR3. |
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The PI3K/AKT pathway regulates cell fate identities during early mouse development |
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Rabbit induced pluripotent stem cells : molecular and functional characterisation of the naive and primed states. |
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RBP-Jkappa-dependent notch signaling is dispensable for mouse early embryonic development. |
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[Reconsidering the roles of female germ cells in ovarian development and folliculogenesis]. |
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Révéler l'identité et le destin des cellules exprimant Notch1 dans les tumeurs intestinales. |
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Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells |
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Ribosome during erythropoiesis. |
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Rififylin, un nouveau gène isolé lors du clonage positionnel d'une mutation létale précoce conditionnelle : analyses développementales et identification de son rôle dans le trafic intracellulaire |
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Rôle des régulateurs post-transcriptionnels Pumilio 1 et Pumilio 2 dans les cellules souches hématopoïétiques murines. |
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Rôle des voies de signalisation dans la spécification des destins cellulaires chez l’embryon précoce de souris. |
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Rôle du facteur de transcription Sox9 dans l'homéostasie et la tumorigenèse intestinales |
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Role of Hacd2 gene during embryogenesis and in the postnatal life of the mouse. |
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Role of signaling pathays in cell-fate specification in the early mouse embryo |
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I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells |
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Study of cell lineage specification occuring during human peri-implantation development. |
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Study of the role of Omcg1 in the maintenance of genome integrity. |
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The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice |
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Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome. |
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Transcription factor activity and nucleosome organization in mitosis |
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Unexpected position-dependent expression of H-2 and beta 2-microglobulin/lacZ transgenes. |
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Unravelling the identity and fate of Notch1-expressing cells within intestinal tumours |
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La voie PI3K/AKT régule l'identité du destin cellulaire au cours du développement précoce de la souris. |
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