Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability |
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Aging yeast cells undergo a sharp entry into senescence unrelated to the loss of mitochondrial membrane potential. |
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Analysis of the intraspecific variability in the yeasts : ammonium and azoles antifungals resistance. |
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Bistability and hysteresis in epigenetic regulation of the lactose operon. Since Delbrück, a long series of ignored models. |
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Braiding DNA: experiments, simulations, and models. |
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Caractérisation de l'entrée en sénescence en utilisant les mutants de longévité et l'intervention concernant les facteurs de vieillissement ERC et ROS |
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Characterisation of senescence entry point using long-lived mutants and intervention related to ageing factors ERC and ROS. |
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COSPLAY: An expandable toolbox for combinatorial and swift generation of expression plasmids in yeast |
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Déchiffrer les dynamiques du vieillissement à l'aide de la microfluidique et de l'apprentissage profond. |
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Deciphering the aging dynamics using microfluidics and deep-learning |
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Discovery of new enzyme activities from environmental samples by ultrahigh-throughput screening |
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Endothelial cilia mediate low flow sensing during zebrafish vascular development |
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Étude de l’antagonisme entre la résistance et la tolérance au stress en réponse au peroxyde d’hydrogène chez la levure bourgeonnante S. cerevisiae. |
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Etude du mécanisme de la sensation du flux ciliaire dans l'organiseur droite gauche du poisson zèbre |
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Etudes des topoisomérases de type II par micromanipulation d'ADN |
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Forced periodic expression of G1 cyclins phase-locks the budding yeast cell cycle |
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Impact des contraintes mécaniques sur la physiologie cellulaire |
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Impact of mechanical stresses on cellular physiology. |
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In silico control of biomolecular processes |
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Increased levels of mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol |
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Long-term imaging in microfluidic devices. |
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Measuring the growth rate of cells, one at a time |
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Mechanisms of asymmetrical segregation of Hsp104-bounded protein aggregates in budding yeast. |
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A memory system of negative polarity cues prevents replicative aging. |
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Mesure de l’hétérogénéité au sein de la population bactérienne monoclonale en gouttelettes microfluidiques ancrées : le cas de la de réponse antibiotique. |
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Multiple inputs ensure yeast cell size homeostasis during cell cycle progression |
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Nonlinear feedback drives homeostatic plasticity in H2O2 stress response. |
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Nucleosome-depleted regions in promoters: consequences on robustness of transcriptional activation |
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Origin of irreversibility of cell cycle start in budding yeast |
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Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development. |
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Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1 |
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Pulse propagation by a capacitive mechanism drives embryonic blood flow. |
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A quantitative approach to study endothelial cilia bending stiffness during blood flow mechanodetection in vivo. |
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Recherche de nouvelles enzymes par criblage fonctionnel à ultra-haut débit. |
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Self-organization of Saccharomyces cerevisiae colonies |
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Single-cell analysis of the antagonism between resistance and tolerance during the adaptive response to hydrogen peroxide in budding yeast |
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Single-molecule study of DNA unlinking by eukaryotic and prokaryotic type-II topoisomerases. |
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Structural studies on RNA polymerase elongation complexes interacting with other cellular machines |
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Study of the role of the cyclin-dependent kinase inhibitor p21Waf1/Cip1 in cellular senescence |
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Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages |
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Ultrasensitivity and positive feedback to promote sharp mitotic entry. |
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Zebrafish left-right organizer : multi-scale analysis of cilia behaviors and flow-sensing mechanism for symmetry-breaking. |
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