Approches de biologie chimique dans la voie NEDD8. |
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BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization |
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Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence |
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Caractérisation de l'ubiquitylation-dégradation médiée par Mdm2, de la protéine oncosuppressive p53 |
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Chemical biology approaches within the NEDD8 pathway |
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Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism |
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Chromatin-bound MDM2, a new player in metabolism. |
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Une coopération métabolique entre le liposarcome et le muscle squelettique favorise la croissance tumorale. |
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Détermination des fonctions du gène E4F1 dans la voie p53 : caractérisation d'un nouveau niveau de régulation impliquant l'oncoprotéine Mdm2 |
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Dexamethasone in hyperleukocytic acute myeloid leukemia |
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E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells |
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E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation. |
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E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis. |
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Etude de l'élément transposable Jockey, chez "Drosophila melanogaster" [premier stage] ; localisation intracellulaire différentielle des voies MAPK activées en réponse aux stress : arsénite et anisomycine [second stage] |
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Etude des fonctions métaboliques de l'oncoprotéine MDM2 : vers de nouveaux traitements thérapeutiques pour le Liposarcome |
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FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer. |
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Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF |
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Implication de la voie p53 dans les syndromes d'insuffisance médullaire |
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Implication of asparagine synthetase in the nutritional requirements of B-cell lymphomas. |
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Implication of the p53 pathway in bone marrow failure syndromes. |
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Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2 |
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Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia. |
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MDM2 controls gene expression independently of p53 in both normal and cancer cells |
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The Mdm2 oncogene : new functions and implications in serine metabolism. |
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A metabolic crosstalk between liposarcoma and skeletal muscle sustains tumor growth |
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Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53. |
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A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter |
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Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells |
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The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms. |
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Rearranged genome as pleomorphic sarcomas oncogene?. |
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Role of the p53 tumor suppressor in metabolism |
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Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia |
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TAG-RNAi overcomes off-target effects in cancer models |
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Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma |
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Targeting mitochondrial metabolism in pancreatic cancer |
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Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation |
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Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis. |
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Transfert de mitochondries des cellules souches mésenchymateuses aux cellules souches de glioblastome : effets sur le métabolisme et la résistance à la chimiothérapie |
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The ubiquitin-protein ligase activity of Hdm2 is inhibited by nucleic acids. |
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[The Yin and the Yang of senescence: is it possible to age without developing cancer?]. |
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