J. Julian Blow Scottish biologist
Blow, J. Julian
Blow, J.
Blow, J. Julian, 19..-....
VIAF ID: 17393935 (Personal)
Permalink: http://viaf.org/viaf/17393935
Preferred Forms
- 200 _ | ‡a Blow ‡b J. Julian
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- 100 1 _ ‡a Blow, J. Julian
- 100 1 _ ‡a Blow, J. Julian
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- 100 1 0 ‡a Blow, J. Julian
- 100 1 _ ‡a Blow, J. Julian
- 100 1 _ ‡a Blow, J. Julian, ‡d 19..-....
- 100 0 _ ‡a J. Julian Blow ‡c Scottish biologist
4xx's: Alternate Name Forms (8)
Works
Title | Sources |
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The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1. | |
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. | |
Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts | |
Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks. | |
Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus | |
Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories. | |
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing | |
Clusters, factories and domains: The complex structure of S-phase comes into focus. | |
Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases | |
The contribution of dormant origins to genome stability: from cell biology to human genetics. | |
Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision. | |
Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins | |
Direct non transcriptional role of NF-Y in DNA replication. | |
DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. | |
DNA replication: stable driving prevents fatal smashes | |
Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos. | |
The dynamics of replication licensing in live Caenorhabditis elegans embryos. | |
Editorial overview | |
Eukaryotic DNA replication, 1996: | |
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. | |
Functional domains of the Xenopus replication licensing factor Cdt1 | |
Ganz geil | |
The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing | |
Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import. | |
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines | |
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing | |
The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability | |
Lgr5+ intestinal stem cells reside in an unlicensed G1 phase. | |
The licensing checkpoint opens up. | |
Many strands converge | |
Molecular Themes in DNA Replication | |
Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination. | |
Nuclear structure and the control of DNA replication in the Xenopus embryo | |
Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system. | |
Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach | |
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192 | |
Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor. | |
PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage | |
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing | |
Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts. | |
Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation. | |
The regulation of chromosome replication | |
The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. | |
Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels. | |
Replication forks, chromatin loops and dormant replication origins | |
Replication occurs at discrete foci spaced throughout nuclei replicating in vitro. | |
Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts | |
Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin | |
The role of cyclin synthesis, modification and destruction in the control of cell division. | |
The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation | |
The role of the replication licensing system in cell proliferation and cancer | |
The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis | |
Stochastic association of neighboring replicons creates replication factories in budding yeast. | |
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis. | |
Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability | |
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells | |
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1. | |
Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes. | |
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. | |
The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin |