Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities |
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Aggressive Hematopoietic Malignancy Characterized by Biallelic Loss of SMARCB1 |
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AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry |
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Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations. |
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ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. |
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BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression. |
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CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas |
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Clinicopathologic and molecular features of intracranial desmoplastic small round cell tumors |
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Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis. |
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Differential nuclear ATRX expression in sarcomas. |
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DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics |
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Do Increased Doses to Stem-Cell Niches during Radiation Therapy Improve Glioblastoma Survival? |
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Entwicklung molekularer Marker zur präzisen Klassifikation von mesenchymalen Tumoren |
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Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma |
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FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma. |
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Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas. |
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Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype |
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Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases |
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IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO. |
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Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma. |
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Intracranial mesenchymal tumors with FET-CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas |
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Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course |
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Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles. |
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Methylation-based classification of benign and malignant peripheral nerve sheath tumors |
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Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology |
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New brain tumor entities emerge from molecular classification of CNS-PNETs |
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Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets |
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Novel, improved grading system(s) for IDH-mutant astrocytic gliomas. |
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Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour |
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Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA |
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Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience. |
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Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations. |
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Primary pulmonary myxoid sarcoma with an unusual gene fusion between exon 7 of EWSR1 and exon 5 of CREB1 |
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Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants. |
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Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions |
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Sarcoma classification by DNA methylation profiling |
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Sclerosing epithelioid mesenchymal neoplasm of the pancreas - a proposed new entity |
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Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations |
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TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma |
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Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities |
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Untersuchungen zur nukleären Lokalisation und Funktion des Proteins "Suppressor of cytokine signaling 1" |
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