Lorsch, Jon.
![Sudoc [ABES], France](/viaf/images/flags/SUDOC.png "Sudoc [ABES], France")
Jon R Lorsch
Lorsch, J. R.
VIAF ID: 166280447 (Personal)
Permalink: http://viaf.org/viaf/166280447
Preferred Forms
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100 0 _
‡a
Jon R Lorsch
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100 1 _
‡a
Lorsch, J. R.
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100 1 _ ‡a Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon
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100 1 _
‡a
Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon
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100 1 _
‡a
Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon
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100 1 _ ‡a Lorsch, Jon.
4xx's: Alternate Name Forms (6)
Works
| Title | Sources |
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| The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway. |
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| Active yeast ribosome preparation using monolithic anion exchange chromatography |
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| ATP and GTP hydrolysis assays (TLC). |
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| Basic science: Bedrock of progress |
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| The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β |
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| Cell Biology. Fixing problems with cell lines |
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| Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon |
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| The DEAD box protein eIF4A. 1. A minimal kinetic and thermodynamic framework reveals coupled binding of RNA and nucleotide |
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| The DEAD box protein eIF4A. 2. A cycle of nucleotide and RNA-dependent conformational changes |
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| Demystifying medicine 2015. The future for biomedical scientists, 2015: |
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| Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo |
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| eIF1 controls multiple steps in start codon recognition during eukaryotic translation initiation |
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| The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo |
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| eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast. |
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| Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy. |
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| The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome |
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| Explanatory chapter: nucleic acid concentration determination |
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| Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNA(Met) and AUG selection |
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| Identification and characterization of functionally critical, conserved motifs in the internal repeats and N-terminal domain of yeast translation initiation factor 4B (yeIF4B) |
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| Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery |
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| Initiation of Protein Synthesis by Hepatitis C Virus Is Refractory to Reduced eIF2 · GTP · Met-tRNAiMet Ternary Complex Availability |
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| Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining. |
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| Laboratory methods in enzymology : protein. |
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| Maximizing the return on taxpayers' investments in fundamental biomedical research |
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| Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation |
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| Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPs in vivo. |
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| N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection |
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| Organizing graduate life sciences education around nodes and connections |
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| The path to perdition is paved with protons |
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| Perspective: Sustaining the big-data ecosystem |
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| Practical steady-state enzyme kinetics |
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| Protein Affinity Purification using Intein/Chitin Binding Protein Tags. |
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| Protein derivitization-expressed protein ligation |
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| Protein filter binding. |
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| Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome |
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| Ribosome recycling step in yeast cytoplasmic protein synthesis is catalyzed by eEF3 and ATP. |
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| Ribozyme catalysis: not different, just worse |
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| RNA chaperones exist and DEAD box proteins get a life |
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| RNA Purification – Precipitation Methods |
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| Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons |
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| rRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit. |
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| Sanger dideoxy sequencing of DNA. |
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| Specific domains in yeast translation initiation factor eIF4G strongly bias RNA unwinding activity of the eIF4F complex toward duplexes with 5'-overhangs |
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| Standard in vitro assays for protein-nucleic acid interactions--gel shift assays for RNA and DNA binding |
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| Structural integrity of {alpha}-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability. |
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| Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae |
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| Translation initiation / edited by Jon Lorsch. - Amsterdam, cop. 2007. |
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| Translation initiation : reconstituted systems and biophysical methods |
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| Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition |
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| Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity |
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| Where to begin? The mechanism of translation initiation codon selection in eukaryotes |
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| Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner |
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| Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity. |
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| Yeast eIF4B binds to the head of the 40S ribosomal subunit and promotes mRNA recruitment through its N-terminal and internal repeat domains |
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| Yeast eukaryotic initiation factor 4B (eIF4B) enhances complex assembly between eIF4A and eIF4G in vivo |
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| β-Hairpin loop of eukaryotic initiation factor 1 (eIF1) mediates 40 S ribosome binding to regulate initiator tRNA(Met) recruitment and accuracy of AUG selection in vivo |
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