Amanda Fosang
Fosang, Amanda
VIAF ID: 14153801 (Personal)
Permalink: http://viaf.org/viaf/14153801
Preferred Forms
- 100 0 _ ‡a Amanda Fosang
- 100 1 _ ‡a Fosang, Amanda
4xx's: Alternate Name Forms (5)
Works
Title | Sources |
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3D Bioprinting of Cartilage for Orthopedic Surgeons: Reading between the Lines | |
The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases. | |
Abundant LacZ activity in the absence of Cre expression in the normal and inflamed synovium of adult Col2a1-Cre; ROSA26RLacZ reporter mice | |
The accumulation of intracellular ITEGE and DIPEN neoepitopes in bovine articular chondrocytes is mediated by CD44 internalization of hyaluronan. | |
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo | |
ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan. | |
ADAMTS-5 takes centre stage in new developments for aggrecanase inhibitors. | |
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro | |
Adamts5-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies | |
Aggrecanase cleavage in juvenile idiopathic arthritis patients is minimally detected in the aggrecan interglobular domain but robust at the aggrecan C-terminus. | |
Bioactivity in an Aggrecan 32-mer Fragment Is Mediated via Toll-like Receptor 2. | |
Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis. | |
Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity | |
Cartilage microRNA dysregulation during the onset and progression of mouse osteoarthritis is independent of aggrecanolysis and overlaps with candidates from end-stage human disease. | |
Connective tissue remodelling in the ovine cervix during pregnancy and at term | |
Cortisol enhances structural maturation of the hypoplastic fetal lung in sheep | |
Cytokine-induced increases in ADAMTS-4 messenger RNA expression do not lead to increased aggrecanase activity in ADAMTS-5-deficient mice. | |
A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers | |
Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice. | |
Emerging Frontiers in cartilage and chondrocyte biology | |
Employing molecular genetics of chondrodysplasias to inform the study of osteoarthritis | |
Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo | |
Evidence of a novel aggrecan-degrading activity in cartilage: Studies of mice deficient in both ADAMTS-4 and ADAMTS-5. | |
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease. | |
Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung | |
High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of osteoarthritis | |
Identifying the human aggrecanase. | |
Increased hyaluronan production in the glomeruli from diabetic rats: a link between glucose-induced prostaglandin production and reduced sulphated proteoglycan | |
Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage. | |
Is cartilage matrix breakdown an appropriate therapeutic target in osteoarthritis--insights from studies of aggrecan and collagen proteolysis? | |
Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens | |
Matrilin-4 is processed by ADAMTS-5 in late Golgi vesicles present in growth plate chondrocytes of defined differentiation state. | |
Matrix Biology Society of Australia and New Zealand. Meeting (27th : 2003 : Acheron, Vic.). Matrix matters, 2003: | |
Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. | |
Matrix metalloproteinases are active following guanidine hydrochloride extraction of cartilage: generation of DIPEN neoepitope during dialysis. | |
Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development | |
Membrane-type 1 MMP (MMP-14) cleaves at three sites in the aggrecan interglobular domain | |
Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth | |
MMP and non-MMP-mediated release of aggrecan and its fragments from articular cartilage: a comparative study of three different aggrecan and glycosaminoglycan assays | |
N-linked keratan sulfate in the aggrecan interglobular domain potentiates aggrecanase activity. | |
Neoepitope Antibodies Against MMP-Cleaved and Aggrecanase-Cleaved Aggrecan | |
Perlecan from human epithelial cells is a hybrid heparan/chondroitin/keratan sulfate proteoglycan. | |
Proteoglycan degradation by the ADAMTS family of proteinases | |
Proteomic characterization of mouse cartilage degradation in vitro | |
Recombinant human aggrecan G1-G2 exhibits native binding properties and substrate specificity for matrix metalloproteinases and aggrecanase | |
Reduction of arthritis severity in protease-activated receptor-deficient mice. | |
The role of hepatocyte growth factor in the humoral regulation of inguinal hernia closure. | |
The sulphation pattern in chondroitin sulphate chains investigated by chondroitinase ABC and ACII digestion and reactivity with monoclonal antibodies | |
To clot or not | |
Transcriptomics of wild-type mice and mice lacking ADAMTS-5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction. | |
Transparency Is the Key to Quality | |
Wide bandwidth nanomechanical assessment of murine cartilage reveals protection of aggrecan knock-in mice from joint-overuse. |