Ariel Fernández Matemático argentino
Fernández, Ariel 1957-
VIAF ID: 122315132 (Personal)
Permalink: http://viaf.org/viaf/122315132
Preferred Forms
4xx's: Alternate Name Forms (5)
Works
| Title | Sources |
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| Folding Cooperativity and the Wrapping of Intermediate States of Soluble Natural Proteins |
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| From residue matching patterns to protein folding topographies: general model and bovine pancreatic trypsin inhibitor. |
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| Golden rule for buttressing vulnerable soluble proteins. |
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| High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design |
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| How do we probe ubiquitin's pathway heterogeneity? |
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| Human capacitance to dosage imbalance: coping with inefficient selection. |
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| Hydration profiles of amyloidogenic molecular structures. |
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| In silico drug profiling of the human kinome based on a molecular marker for cross reactivity. |
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| Induced disorder in protein-ligand complexes as a drug-design strategy. |
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| Insufficient hydrogen-bond desolvation and prion-related disease. |
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| Insufficiently dehydrated hydrogen bonds as determinants of protein interactions |
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| Intrinsic Fluctuations in Macromolecular Self-Replicating Systems |
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| Is there a case for selectively promiscuous anticancer drugs? |
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| Keeping dry and crossing membranes. |
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| Kinetic assembling of the biologically active secondary structure for CAR, the target sequence for the Rev protein of HIV-1. |
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| Large-scale context in protein folding: villin headpiece. |
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| Last Frontier and Back to the Drawing Board: Protein–Water Interfacial Tension in Drug Design |
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| mathematical approach to protein biophysics |
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| Membrane thickness cue for cold sensing in a bacterium. |
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| Modulating drug impact by wrapping target proteins. |
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| Molecular basis for evolving modularity in the yeast protein interaction network. |
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| Molecular dimension explored in evolution to promote proteomic complexity |
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| Multitarget Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology |
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| Nanoscale thermodynamics of biological interfacial tension |
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| Noncoexisting structural elements in catalytic pre-messenger RNA's. |
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| Nucleation theory for helix unfolding in peptide chains. |
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| On renormalisation of fluctuations at the onset of a centre manifold |
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| The onset of macroscopically detectable amplification of template concentration for self-replicating RNA. |
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| Optical implementation of the generalized Hough transform with totally incoherent light. |
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| Optical processing of color images with incoherent illumination: orientation-selective edge enhancement using a modified liquid-crystal display. |
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| Packing defects as selectivity switches for drug-based protein inhibitors |
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| Packing defects functionalize soluble proteins. |
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| Partial relaxation of enzyme-product binding by refolding of the growing chain in autocatalytic RNA replication. |
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| Passive water-lipid peptide translocators with conformational switches: from single-molecule probe to cellular assay. |
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| Pathway diversity and concertedness in protein folding: an ab-initio approach. |
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| Pause sites and regulatory role of secondary structure in RNA replication. |
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| Peptide translocators with engineered dehydration-prone hydrogen bonds. |
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| Pharmaceutical Industry at the Post-Genomic Junction |
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| Physics at the biomolecular interface, 2016: |
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| Prediction of the Sugar Mill Shaft Failure Using a Fracture Mechanics Method |
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| Preservation of a kinetically originated folding of the cis antirepressor sequence for transport of HIV-1 viral RNA. |
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| The principle of minimal episteric distortion of the water matrix and its steering role in protein folding. |
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| Productive induced metastability in allosteric modulation of kinase function. |
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| Protein Cooperativity and Wrapping: Two Themes in the Transformative Platform of Molecular Targeted Therapy |
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| Protein packing defects "heat up" interfacial water. |
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| Protein promiscuity: drug resistance and native functions--HIV-1 case. |
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| Protein structure protection commits gene expression patterns. |
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| Protein Under-wrapping Causes Dosage Sensitivity and Decreases Gene Duplicability |
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| Proteins with H-bond packing defects are highly interactive with lipid bilayers: Implications for amyloidogenesis. |
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| Provisional theory of nanoscale water dielectrics |
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| Rational drug redesign to overcome drug resistance in cancer therapy: imatinib moving target. |
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| Reconstruction of perspective shifts and refocusing of a three-dimensional scene from a multi-focus image stack. |
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| Redesigning kinase inhibitors to enhance specificity. |
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| Selective antagonism of anticancer drugs for side-effect removal. |
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| Selectivity filters to edit out deleterious side effects in kinase inhibitors. |
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| Self-organisation in the centre manifold of a dissipative system |
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| Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches |
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| Solvent-exposed backbone loosens the hydration shell of soluble folded proteins. |
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| Statistical mechanical model for proton transfer in RNA |
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| Statistics of Disordered Polymers: An Effective Hamiltonian and its Associated Gibbs Measure |
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| Stochastic dynamical constraints in de novo RNA replication. |
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| Structural defects and the diagnosis of amyloidogenic propensity |
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| Structure-induced strain determining the internal cyclization site in the yeast cobI5 autocatalytic intron: theory and experimental tests. |
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| Sub-nanoscale surface ruggedness provides a water-tight seal for exposed regions in soluble protein structure. |
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| Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances. |
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| Supramolecular Evolution of Protein Organization. |
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| Synergizing immunotherapy with molecular-targeted anticancer treatment. |
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| Taming the induced folding of drug-targeted kinases. |
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| Targeted therapy to annihilate the immune-evading phenotype in cancer evolution. |
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| Theory of scaling for fluctuations in thermal explosion conditions |
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| Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma. |
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| Time-resolved backbone desolvation and mutational hot spots in folding proteins. |
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| Topology to geometry in protein folding: beta-lactoglobulin |
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| Transformative concepts for drug design : target wrapping |
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| Turning promiscuous kinase inhibitors into safer drugs. |
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| Under-Wrapped Proteins in the Order–Disorder Twilight: Unraveling the Molecular Etiology of Aberrant Aggregation |
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| Wrapper Drugs for Personalized Medicine |
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| Wrapping as a Selectivity Filter for Molecular Targeted Therapy: Preliminary Evidence |
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| Wrapping-Based Re-engineering of an Anticancer Drug to Make it Safer |
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| Wrapping Deficiencies and De-wetting Patterns in Soluble Proteins: A Blueprint for Drug Design |
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| Wrapping Drug Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology |
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| Wrapping mimicking in drug-like small molecules disruptive of protein-protein interfaces. |
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| Wrapping Patterns as Universal Markers for Specificity in the Therapeutic Interference with Signaling Pathways |
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| Wrapping technology and the enhancement of specificity in cancer drug treatment. |
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