Virtual International Authority File


David Sinclair Australian biologist and geneticist Wikidata

Sinclair, David (David A.) Library of Congress/NACO

VIAF ID: 101558867 (Personal)


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Abstracts of papers presented at the 2008 meeting on molecular genetics of aging, September 24-September 28, 2008, 2008: Library of Congress/NACO
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Wikidata
The ageing epigenome: damaged beyond repair? Wikidata
Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells Wikidata
Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene. Wikidata
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation. Wikidata
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Wikidata
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Wikidata
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism. Wikidata
Characterization of murine SIRT3 transcript variants and corresponding protein products. Wikidata
David A. Sinclair, Ph.D is interviewed by Vicki Glaser. Wikidata
Design and synthesis of compounds that extend yeast replicative lifespan. Wikidata
Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors. Wikidata
Dietary restriction: standing up for sirtuins. Wikidata
Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment Wikidata
The enzyme CD38 (a NAD glycohydrolase, EC is necessary for the development of diet-induced obesity. Wikidata
Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome. Wikidata
GLTSCR2/PICT1 links mitochondrial stress and Myc signaling. Wikidata
Guidelines for the use and interpretation of assays for monitoring autophagy Wikidata
Identification of a SIRT1 mutation in a family with type 1 diabetes. Wikidata
The intersection between aging and cardiovascular disease. Wikidata
Measurement of sirtuin enzyme activity using a substrate-agnostic fluorometric nicotinamide assay. Wikidata
The "metabolic winter" hypothesis: a cause of the current epidemics of obesity and cardiometabolic disease. Wikidata
Mosquito larval source management for controlling malaria Wikidata
A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse. Wikidata
Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity? Wikidata
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein. Wikidata
Paradigms and pitfalls of yeast longevity research. Wikidata
Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae. Wikidata
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice Wikidata
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice. Wikidata
Resveratrol inhibits pathologic retinal neovascularization in Vldlr(-/-) mice Wikidata
The role of nuclear architecture in genomic instability and ageing. Wikidata
Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase Wikidata
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet Wikidata
SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance. Wikidata
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth Wikidata
SIRT1 is essential for normal cognitive function and synaptic plasticity Wikidata
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function Wikidata
SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity Wikidata
SIRT2 controls the pentose phosphate switch. Wikidata
Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy. Wikidata
Sirtuins: a conserved key unlocking AceCS activity. Wikidata
Small-molecule allosteric activators of sirtuins. Wikidata
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass Wikidata
Toward a unified theory of caloric restriction and longevity regulation. Wikidata
TPE or not TPE? It's no longer a question. Wikidata
Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. Wikidata
Xenohormesis: sensing the chemical cues of other species. Wikidata
Yeast life-span extension by calorie restriction is independent of NAD fluctuation. Wikidata

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