Siderovski, David P.
David Siderovski Canadian American pharmacologist
VIAF ID: 32284583 (Personal)
Permalink: http://viaf.org/viaf/32284583
Preferred Forms
- 100 0 _ ‡a David Siderovski ‡c Canadian American pharmacologist
- 200 _ | ‡a Siderovski ‡b David P.
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- 100 1 _ ‡a Siderovski, David P.
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- 100 1 _ ‡a Siderovski, David P.
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- 100 1 _ ‡a Siderovski, David P.
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- 100 1 _ ‡a Siderovski, David P.
4xx's: Alternate Name Forms (3)
Works
Title | Sources |
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Covalent immobilization of histidine-tagged proteins for surface plasmon resonance | |
Crystal structure of the multifunctional Gβ5–RGS9 complex | |
D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides. | |
Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins | |
The effect of RGS12 on PDGFbeta receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cells | |
Entamoeba histolytica RacC selectively engages p21-activated kinase effectors | |
Exome sequencing in 53 sporadic cases of schizophrenia identifies 18 putative candidate genes | |
Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA | |
G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13) | |
The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention. | |
Galpha12/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors | |
Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq | |
Genetic deletion of Rgs12 in mice affects serotonin transporter expression and function in vivo and ex vivo | |
Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance | |
Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae. | |
Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding. | |
GPCR high throughput screening (part 1) | |
GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling | |
Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. | |
High-affinity immobilization of proteins using biotin- and GST-based coupling strategies | |
A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization | |
Inhibition of dopamine transporter activity by G protein βγ subunits | |
Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions. | |
Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA. | |
LGN regulates mitotic spindle orientation during epithelial morphogenesis | |
Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina | |
Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer | |
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. | |
Modulating platelet reactivity through control of RGS18 availability. | |
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | |
A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation | |
Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice | |
A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis | |
PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation | |
A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics | |
Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine | |
Profound block in thymocyte development in mice lacking p56lck | |
Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation. | |
Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides. | |
Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins | |
The R6A-1 peptide binds to switch II of Galphai1 but is not a GDP-dissociation inhibitor | |
Random mutagenesis of the human immunodeficiency virus type-1 trans-activator of transcription (HIV-1 Tat) | |
Receptor-mediated activation of heterotrimeric G-proteins: current structural insights. | |
Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model | |
Regulation of T cell activation, anxiety, and male aggression by RGS2. | |
Regulators of G-protein signaling | |
Return of the GDI: the GoLoco motif in cell division. | |
The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face | |
Rgs1 regulates multiple Galpha subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism. | |
RGS12 interacts with the SNARE-binding region of the Cav2.2 calcium channel | |
Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins | |
RIC-8 is required for GPR-1/2-dependent Galpha function during asymmetric division of C. elegans embryos | |
Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling | |
Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation | |
A set of human putative lymphocyte G0/G1 switch genes includes genes homologous to rodent cytokine and zinc finger protein-encoding genes | |
Single Nucleotide Polymorphisms in Chemosensory Pathway Genes GNB3, TAS2R19, and TAS2R38 Are Associated with Chronic Rhinosinusitis | |
State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics. | |
Structural and evolutionary division of phosphotyrosine binding (PTB) domains. | |
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors | |
Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits | |
Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis | |
Structural determinants underlying the temperature-sensitive nature of a Galpha mutant in asymmetric cell division of Caenorhabditis elegans | |
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein -subunits | |
Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange | |
Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo | |
The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. | |
Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism | |
Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos | |
Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica. | |
β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids |