Todd Golub
Golub, Todd R.
VIAF ID: 63469252 (Personal)
Permalink: http://viaf.org/viaf/63469252
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Golub, Todd R.
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Todd Golub
4xx's: Alternate Name Forms (3)
Works
| Title | Sources |
|---|---|
| LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures |
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| Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers |
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| A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1 |
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| A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer |
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| Melanoma genome sequencing reveals frequent PREX2 mutations |
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| Metagenes and molecular pattern discovery using matrix factorization |
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| A metastasis map of human cancer cell lines |
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| MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes |
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| MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a |
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| MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer |
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| microRNA expression during trophectoderm specification |
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| MicroRNA expression profiles classify human cancers |
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| MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia |
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| MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors |
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| MicroRNA miR-125a controls hematopoietic stem cell number |
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| The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection |
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| miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells |
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| Mitochondrial metabolism promotes adaptation to proteotoxic stress |
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| MLL-rearranged leukemias: insights from gene expression profiling |
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| MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia |
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| Modeling genomic diversity and tumor dependency in malignant melanoma |
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| Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response |
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| Molecular sampling of prostate cancer: a dilemma for predicting disease progression |
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| The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. |
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| MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia |
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| mRNA expression signature of Gleason grade predicts lethal prostate cancer |
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| MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells |
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| mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways |
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| Multiplex cytological profiling assay to measure diverse cellular states |
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| Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action |
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| Mutational heterogeneity in cancer and the search for new cancer-associated genes |
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| A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer |
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| Next-generation characterization of the Cancer Cell Line Encyclopedia |
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| A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. |
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| NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes |
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| Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. |
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| Noncanonical open reading frames encode functional proteins essential for cancer cell survival |
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| An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis |
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| Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
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| Patient-derived xenografts undergo mouse-specific tumor evolution. |
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| PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES |
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| A phase II study of the EGFR inhibitor gefitinib in patients with acute myeloid leukemia |
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| Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine |
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| Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies |
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| Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance |
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| Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis |
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| Prolonged therapy for hepatitis C with low-dose peginterferon. |
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| Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model |
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| Protection of tissue physicochemical properties using polyfunctional crosslinkers. |
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| Proteomic and genetic approaches identify Syk as an AML target |
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| PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA. |
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| Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes |
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| Punctuated evolution of prostate cancer genomes |
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| Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG |
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| Recurrent and functional regulatory mutations in breast cancer |
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| A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers |
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| Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice. |
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| An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray. |
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| Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry |
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| Selective killing of cancer cells by a small molecule targeting the stress response to ROS |
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| Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution |
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| Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer |
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| Sequence analysis of mutations and translocations across breast cancer subtypes |
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| SF3B1 and other novel cancer genes in chronic lymphocytic leukemia |
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| Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma |
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| Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program |
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| Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma |
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| Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1) |
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| The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1 |
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| SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression |
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| Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors |
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| Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing |
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| Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy |
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| Stem cell gene expression programs influence clinical outcome in human leukemia. |
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| STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability |
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| A strategy for oligonucleotide microarray probe reduction |
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| Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP |
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| Subclass mapping: identifying common subtypes in independent disease data sets |
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| SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas |
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| Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q |
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| Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals |
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| Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles |
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| Targetable genetic features of primary testicular and primary central nervous system lymphomas |
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| Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. |
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| Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state |
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| Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling |
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| Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling |
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| A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer. |
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| Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. |
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| Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory |
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| Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer |
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| Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy |
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| WRN helicase is a synthetic lethal target in microsatellite unstable cancers |
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| A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility |
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