Todd Golub
Golub, Todd R.
VIAF ID: 63469252 (Personal)
Permalink: http://viaf.org/viaf/63469252
Preferred Forms
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100 1 _ ‡a Golub, Todd R.
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100 0 _ ‡a Todd Golub
4xx's: Alternate Name Forms (3)
Works
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LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures |
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Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers |
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A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1 |
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A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer |
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Melanoma genome sequencing reveals frequent PREX2 mutations |
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Metagenes and molecular pattern discovery using matrix factorization |
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A metastasis map of human cancer cell lines |
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MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes |
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MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a |
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MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer |
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microRNA expression during trophectoderm specification |
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MicroRNA expression profiles classify human cancers |
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MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia |
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MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors |
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MicroRNA miR-125a controls hematopoietic stem cell number |
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The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection |
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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. |
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Mitochondrial metabolism promotes adaptation to proteotoxic stress |
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MLL-rearranged leukemias: insights from gene expression profiling |
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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia |
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Modeling genomic diversity and tumor dependency in malignant melanoma |
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Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response |
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Molecular sampling of prostate cancer: a dilemma for predicting disease progression |
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The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. |
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MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia |
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mRNA expression signature of Gleason grade predicts lethal prostate cancer |
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MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells |
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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways |
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Multiplex cytological profiling assay to measure diverse cellular states |
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Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action |
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Mutational heterogeneity in cancer and the search for new cancer-associated genes |
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A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer |
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Next-generation characterization of the Cancer Cell Line Encyclopedia |
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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. |
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NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes |
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Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. |
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Noncanonical open reading frames encode functional proteins essential for cancer cell survival |
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An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis |
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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
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Patient-derived xenografts undergo mouse-specific tumor evolution. |
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PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES |
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A phase II study of the EGFR inhibitor gefitinib in patients with acute myeloid leukemia |
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Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine |
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Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies |
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Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance |
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Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis |
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Prolonged therapy for hepatitis C with low-dose peginterferon. |
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Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model |
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Protection of tissue physicochemical properties using polyfunctional crosslinkers. |
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Proteomic and genetic approaches identify Syk as an AML target |
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PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA. |
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Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes |
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Punctuated evolution of prostate cancer genomes |
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Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG |
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Recurrent and functional regulatory mutations in breast cancer. |
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A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers |
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Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice. |
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An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray. |
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Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry |
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Selective killing of cancer cells by a small molecule targeting the stress response to ROS |
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Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution |
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Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer |
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Sequence analysis of mutations and translocations across breast cancer subtypes |
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SF3B1 and other novel cancer genes in chronic lymphocytic leukemia |
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Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma |
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Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program |
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Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma |
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Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1) |
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The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1 |
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SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression |
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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors |
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Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing |
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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy |
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Stem cell gene expression programs influence clinical outcome in human leukemia. |
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STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability |
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A strategy for oligonucleotide microarray probe reduction |
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Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP |
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Subclass mapping: identifying common subtypes in independent disease data sets |
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SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas |
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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q |
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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals |
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Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles |
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Targetable genetic features of primary testicular and primary central nervous system lymphomas |
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Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. |
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Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state |
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Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling |
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Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling |
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A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer. |
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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. |
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Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory |
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Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer |
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Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy |
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WRN helicase is a synthetic lethal target in microsatellite unstable cancers |
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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility |
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