Jung, Manfred.
Jung, Manfred, 1966-
Jung, Manfred 19..-.... professeur
Manfred Jung researcher
VIAF ID: 96782928 ( Personal )
Permalink: http://viaf.org/viaf/96782928
Preferred Forms
- 200 _ | ‡a Jung ‡b Manfred ‡f 19..-.... ‡c professeur
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- 100 1 _ ‡a Jung, Manfred
- 100 1 _ ‡a Jung, Manfred
- 100 1 _ ‡a Jung, Manfred
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- 100 1 _ ‡a Jung, Manfred ‡d 1966-
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- 100 0 _ ‡a Manfred Jung ‡c researcher
4xx's: Alternate Name Forms (4)
5xx's: Related Names (1)
Works
Title | Sources |
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Activation of sirtuin 2 inhibitors employing photoswitchable geometry and aqueous solubility | |
Azologization and repurposing of a hetero-stilbene-based kinase inhibitor: towards the design of photoswitchable sirtuin inhibitors | |
Beitrag gestörter epigenetischer Regulation zur veränderten Hämoglobinexpression bei der juvenilen myelomonozytären Leukämie | |
BET proteins regulate expression of Osr1 in early kidney development | |
Beurteilung der Gefährlichkeit neuer psychoaktiver Substanzen aus Daten zu Vergiftungen, Prävalenz und Pharmakologie | |
Bioreductive prodrugs for the targeting of epigenetic enzymes | |
Carbamates as potential prodrugs and a new<br>warhead for HDAC inhibition | |
Chemical genetics screen identifies epigenetic mechanisms involved in dopaminergic and noradrenergic neurogenesis in zebrafish | |
Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression | |
Chromatinsignaturen von Kardiomyozyten nach pathologischer Hypertrophie und mechanischer Entlastung | |
Clostridiale Glukosylierende Toxine: Untersuchungen zur Autoprozessierung von Clostridium sordellii Letalem Toxin und Clostridium novyi alpha-Toxin sowie funktionelle Charakterisierung von Clostridium perfringens TpeL-Toxin | |
Continuous fluorescent sirtuin activity assay based on fatty acylated lysines | |
Defined stereoisomers of 2″-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase | |
Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death | |
Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity | |
Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties | |
Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration | |
Development of first-in-class dual Sirt2/HDAC6 inhibitors as molecular tools for dual inhibition of tubulin deacetylation | |
Dynamische DNA-Methylierung in Kardiomyozyten | |
Effects of environmental conditions on nephron number: modeling maternal disease and epigenetic regulation in renal development | |
Einfluss von epigenetischen Inhibitoren auf die Transkription in ES-Zell-abgeleiteten Kardiomyozyten | |
Entwicklung eines In-vitro-Aktivitätstestsystems und selektiver Hemmstoffe für die Histondesacetylase 10 | |
Entwicklung eines Verfahrens zur antimikrobiellen Ausstattung von Papier durch chemisch gebundenes Desinfektionsmittel | |
Entwicklung von fluoreszenzbasierten In-vitro-Assays zur Identifizierung von Hemmstoffen für NAD+-abhängige Enzyme am Beispiel der Clostridium difficile-Transferase und Sirt5 | |
Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis | |
Epigenetic targets in drug discovery | |
Epigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader–Willi Syndrome | |
Etablierung eines dreidimensionalen Kokulturmodells und Testung epigenetisch-aktiver Hemmstoffe beim Multiplen Myelom | |
Ex vivo propagation in a novel 3D high-throughput co-culture system for multiple myeloma | |
Exploring the potential of nucleoside analogues for the lysine methyltransferases KMT9 and METTL21A | |
First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement | |
Handlungswissen, Orientierungswissen, Existenzwissen | |
HDAC8 : a multifaceted target for therapeutic interventions | |
High-throughput 1,536-well fluorescence polarization assays for alpha(1)-acid glycoprotein and human serum albumin binding | |
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo | |
histone code reader Spin1 controls skeletal muscle development | |
Histone deacetylase 6 inhibitor JS28 prevents pathological gene expression in cardiac myocytes | |
Identification and characterization of underlying mechanisms of the adverse effects of DEHP on myeloid hematopoiesis | |
Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform | |
Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing | |
Identifizierung und Charakterisierung neuer Modulatoren der humanen Sirtuine 1, 2 und 3 | |
Implication of epigenetic modifications in response to chemotherapies in gastric cancer : therapeutic perspectives. | |
Kappa but not delta or mu opioid receptors form homodimers at low membrane densities | |
Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy | |
Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference | |
Metabolic response to XD14 treatment in human breast cancer cell line MCF-7 | |
Metabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways | |
Modulation of microtubule acetylation by the interplay of TPPP/p25, SIRT2 and new anticancer agents with anti-SIRT2 potency | |
Neuartige synthetische Cannabinoide in der forensischen Toxikologie : Identifizierung, Metabolismus und Nachweis in Urinproben | |
Neue Testsysteme für Histonmethyltransferasen und Histondemethylasen | |
Niedermolekulare Liganden des epigenetischen Reader-Proteins Spindlin1: Entwicklung von In-vitro-Testsystemen, Screening und Synthese | |
Photoreductive [beta]-aminoalkylation with amino acids affords functionalized [gamma]-aminoketones for nucleoside mimics | |
potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs | |
Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes | |
PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells | |
Proteolysis targeting chimeras (PROTACs) for epigenetics research | |
Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs) | |
Real-life-Analysen zur Arzneimitteltherapie in der Hämatologie und Onkologie: Der Einsatz systemischer Antimykotika und die Prävalenz potentieller Arzneimittelinteraktionen | |
Der Ring des Nibelungen | |
Schistosoma mansoni sirtuins: characterization and potential as chemotherapeutic targets | |
Schrittweise Implementierung von Dose Banding bei der onkologischen Chemotherapie mit Hilfe analytischer Methoden und Fehlerassessment bei hochkomplexen Chemotherapien zur Optimierung der Arzneimitteltherapiesicherheit und Wirtschaftlichkeit | |
Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking | |
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site | |
Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases | |
Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke schistosoma mansoni | |
Structural insights into a novel histone methyltransferase - KMT9 | |
Structure-based design, docking and binding free energy calculations of A366 derivatives as spindlin1 inhibitors | |
Structure‐based design, synthesis, and biological evaluation of triazole‐based smHDAC8 inhibitors | |
Structure‐based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases | |
Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity | |
Substrates and methods for the characterisation of DNA and RNA modifying enzymes: application to TET oxygenases | |
Synthese und biologische Aktivitätsbestimmung von Inhibitoren der Lysin-spezifischen Demethylase 1 | |
Syntheses of Thailandepsin B pseudo‐natural products: access to new highly potent HDAC inhibitors via late‐stage modification | |
Synthesis and testing of inhibitors for jumonjiC domain-containing histone demethylases | |
Synthetische Cannabinoide in der forensischen Toxikologie : Studien zur Pharmakokinetik mittels massenspektrometrischer Analyseverfahren in biologischen Matrices | |
Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy | |
Validation of slow off-kinetics of sirtuin rearranging ligands (SirReals) by means of the label-free electrically switchable nanolever technology | |
Wagner : the epic story of an enigmatic musical genius | |
Zelluläre Charakterisierung von Hemmstoffen der Histon-Acetyltransferasen und -Desacetylasen | |
Zielgerichtete Inhibition der Lysin-spezifischen Demethylase 1 (LSD1) mittels Nitroreduktase-Prodrugs |