Genome-wide DNA methylation profiling in early stage I lung adenocarcinoma reveals predictive aberrant methylation in the promoter region of the long noncoding RNA PLUT: an exploratory study |
|
Genomic footprints of activated telomere maintenance mechanisms in cancer |
|
Germline variants of CYBA and TRPM4 predispose to familial colorectal cancer |
|
halobacterium salinarum taxis signal transduction network a protein-protein interaction study |
|
Harmonization and standardization of panel-based tumor mutational burden measurement: real-world results and recommendations of the quality in pathology study |
|
HilbertCurve: an R/Bioconductor package for high-resolution visualization of genomic data |
|
Homozygous missense mutation in the LMAN2L gene segregates with intellectual disability in a large consanguineous Pakistani family |
|
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response |
|
Hypermutation of the inactive X chromosome is a frequent event in cancer |
|
Hypermutation takes the driver's seat |
|
Identification and prioritization of causal variants of human genetic disorders from exome or whole genome sequencing data |
|
Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases |
|
Identification of transient receptor potential channel 4-associated protein as a novel candidate gene causing congenital primary hypothyroidism |
|
IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment |
|
IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas |
|
Immunohistochemical detection of inhibitor of DNA binding 3 mutational variants in mature aggressive B-cell lymphoma |
|
Impact of clinical exomes in neurodevelopmental and neurometabolic disorders |
|
Inferring structural variant cancer cell fraction |
|
Investigation of rare non-coding variants in familial multiple myeloma |
|
iTReX: Interactive exploration of mono- and combination therapy dose response profiling data |
|
landscape of viral associations in human cancers |
|
Loss of function of PGAP1 as a cause of severe encephalopathy identified by whole exome sequencing: lessons of the bioinformatics pipeline |
|
Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions |
|
Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature |
|
MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells |
|
Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories |
|
Molecular profiling-based decision for targeted therapies in IDH wild-type glioblastoma |
|
Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa |
|
Multi-omics profiling of JMML HSPCs reveals onco-fetal reprogramming and identifies novel prognostic biomarkers and therapeutic targets in high-risk JMML [Abstract] |
|
Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma |
|
mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma |
|
mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing |
|
Mutational patterns and regulatory networks in epigenetic subgroups of meningioma |
|
Mutational signatures in germinal center derived B-cell lymphomas from adult patients analyzed in the ICGC MMML-SEQ consortium [Abstract] |
|
MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation |
|
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis |
|
Neutral tumor evolution? [Letter] |
|
New brain tumor entities emerge from molecular classification of CNS-PNETs |
|
Next-generation personalised medicine for high-risk paediatric cancer patients – the INFORM pilot study |
|
NFM-11: pediatric meningiomas are molecularly distinct from adult counterparts [Abstract] |
|
Non-invasive molecular profiling for therapy monitoring of ALK+ lung cancer [Abstract] |
|
NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis |
|
A novel homozygous ARL13B variant in patients with Joubert syndrome impairs its guanine nucleotide-exchange factor activity |
|
Nuclei isolation from fresh frozen brain tumors for single-nucleus RNA-seq and ATAC-seq |
|
OC 34 - Onco-fetal programming drives high-risk juvenile myelomonocytic leukemia, which can be targeted by anti-CD52 treatment [Abstract] |
|
OS12.7. A characterization of intra-tumoral heterogeneity and differential immune activation during malignant progression of meningiomas on single cell level |
|
OTHR-04. Development of a functional plattform for real-time personalized drug sensitivity profiling of patient-derived 3D fresh tumor tissue cultures in the pediatric precision oncology program INFORM [Abstract] |
|
Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern |
|
Patient-by-patient deep transfer learning for drug-response profiling using confocal fluorescence microscopy of pediatric patient-derived tumor-cell spheroids |
|
Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy |
|
PCBP1 gene encoding poly(rc) binding protein i is recurrently mutated in Burkitt lymphoma |
|
PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma |
|
Pheno-seq: linking visual features and gene expression in 3D cell culture systems |
|
Precision oncology based on omics data: the NCT Heidelberg experience |
|
Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation |
|
Protease activation mutants elicit protective immunity against highly pathogenic avian influenza viruses of subtype H7 in chickens and mice |
|
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia |
|
Reconstruction of rearranged T‐cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T‐cell prolymphocytic leukemia |
|
A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma |
|
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing |
|
Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols |
|
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma |
|
A report of whole-genome sequencing in neurologic Wilson's disease [Letter] |
|
Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance |
|
Response to "Unexpected mutations after CRISPR–Cas9 editing in vivo" |
|
A scoping review of distributed ledger technology in genomics: thematic analysis and directions for future research |
|
Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations |
|
Serial liquid biopsies for detection of treatment failure and profiling of resistance mechanisms in KLC1–ALK-rearranged lung cancer |
|
ShinyButchR: interactive NMF-based decomposition workflow of genome-scale datasets |
|
Signatures of mutational processes in human cancer |
|
Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity |
|
Stroma AReactive Invasion Front Areas (SARIFA) proves prognostic relevance in gastric carcinoma and is based on a tumor–adipocyte interaction indicating an altered immune response |
|
Systematic evaluation of somatic cis-regulatory mutations in follicular lymphoma [Abstract] |
|
T‐cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level |
|
TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus |
|
TB-17A: comprehensive pan-cancer analysis of childhood malignancies [Abstract] |
|
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis |
|
Timed Ang2-targeted therapy identifies the Angiopoietin–tie pathway as key regulator of fatal lymphogenous metastasis |
|
Transcriptional and genomic intra-tumor heterogeneity drives subclone specific drug responses in diffuse large B cell lymphoma [Abstract] |
|
transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium |
|
Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking |
|
Tumor cell network integration in glioma represents a stemness feature |
|
Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas |
|
Übersicht: Chancen und Herausforderungen von Big Data in der Onkologie |
|
What do we learn from high-throughput protein interaction data? |
|
Whole-exome sequencing identifies a novel germline variant in PTK7 gene in familial colorectal cancer |
|
whole-genome landscape of medulloblastoma subtypes |
|
Whole genome sequencing reveals DICER1 as a candidate predisposing gene in familial Hodgkin lymphoma [Letter] |
|
YAP1-fusions in pediatric NF2-wildtype meningioma |
|