Virtual International Authority File


Antonín Holý český chemik Wikidata

Holý, Antonín, 1936-2012 National Library of the Czech Republic

VIAF ID: 84009611 (Personal)


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6-oxopurine phosphoribosyltransferase: a target for the development of antimalarial drugs. Wikidata
9-(S)-(2,3-Dihydroxypropyl)adenine inhibits the transformation of chick embryo fibroblasts infected with Rous sarcoma virus: Evidence for inhibition of enzymatic activity of isolated cellular protein kinases by the drug. Wikidata
Activation by 9-(R)-[2-(phosphonomethoxy)propyl]adenine of chemokine (RANTES, macrophage inflammatory protein 1alpha) and cytokine (tumor necrosis factor alpha, interleukin-10 [IL-10], IL-1beta) production. Wikidata
Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice. Wikidata
Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position. Wikidata
Acyklické analogy nukleosidů a nukleotidů s modifikovanými purinovými bázemi National Library of the Czech Republic
Aliphatic analogues of nucleotides: synthesis and affinity towards nucleases. Wikidata
Analoga nukleosidů a nukleotidů: syntéza a biologická účinnost : [Autoreferát doktor. dis.] National Library of the Czech Republic
Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures. Wikidata
Antiviral activity of tenofovir against Cauliflower mosaic virus and its metabolism in Brassica pekinensis plants. Wikidata
Antiviral effect of HPMPC (Cidofovir®), entrapped in cationic liposomes: in vitro study on MDBK cell and BHV-1 virus. Wikidata
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines. Wikidata
Antonín Holý National Library of the Czech Republic
Arrest of Trypanosoma brucei rhodesiense and T. brucei brucei in the S-phase of the cell cycle by (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine ((S)-HPMPA). Wikidata
The binding site for the 3'-terminus of aminoacyl-tRNA in the molecule of elongation factor Tu from Escherichia coli. Wikidata
Determination of the antioxidative activity of substituted 5-aminopyrimidines. Wikidata
Distinct modulation of telomere length in two T-lymphoblastic leukemia cell lines by cytotoxic nucleoside phosphonates PMEG and PMEDAP. Wikidata
Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing Wikidata
Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo Wikidata
Esterifikace fosfonátových analogů nukleotidů National Library of the Czech Republic
Evaluation of the impact of S-adenosylhomocysteine metabolic pools on cytosine methylation of the tobacco genome. Wikidata
Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance. Wikidata
Genotoxicity of purine acyclic nucleotide analogs. Wikidata
Influence of Acyclic Nucleoside Phosphonate Antivirals on Gene Expression of Chemokine Receptors CCR5 and CXCR4. Wikidata
Inhibition of avian myeloblastosis virus reverse transcriptase by diphosphates of acyclic phosphonylmethyl nucleotide analogues Wikidata
Inhibition of nucleoside-binding sites by nucleoside analogues in Escherichia coli. Wikidata
The inhibition of peptidyl transferase activity by aminoacyl derivatives of some nucleoside aliphatic analogues. Wikidata
Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates. Wikidata
Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication. Wikidata
Interaction between dehydrogenases and a new NAD -isomer. Wikidata
Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes. Wikidata
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine. Wikidata
Involvement of MAP kinases in the cytotoxicity of acyclic nucleoside phosphonates. Wikidata
The metabolism of isocytidine in Escherichia coli Wikidata
Metabolism of pyrimidine L-nucleosides Wikidata
A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity Wikidata
A neoceptor approach to unraveling microscopic interactions between the human A2A adenosine receptor and its agonists. Wikidata
New prodrugs of Adefovir and Cidofovir. Wikidata
Novel acyclic nucleoside phosphonate analogues with potent anti-hepatitis B virus activities. Wikidata
A novel and efficient one-pot synthesis of symmetrical diamide Wikidata
A novel selective broad-spectrum anti-DNA virus agent. Wikidata
Oligonucleotide conformations. 4. Temperature and solvent effects on different uridylyl-uridines. Wikidata
Oligonucleotide conformations. Optical studies on GpU analogues with modified-uridine residues. Wikidata
Phosphonylmethoxyalkylpurines and -pyrimidines as inhibitors of African swine fever virus replication in vitro. Wikidata
Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents Wikidata
PMEDAP and its N6-substituted derivatives: genotoxic effect and apoptosis in in vitro conditions. Wikidata
Principy bioorganické chemie ve vývoji a antivirotik a cytostatik National Library of the Czech Republic
Role of caspases and CD95/Fas in the apoptotic effects of a nucleotide analog PMEG in CCRF-CEM cells. Wikidata
(S)-9-(2,3-Dihydroxypropyl)adenine: an aliphatic nucleoside analog with broad-spectrum antiviral activity Wikidata
[Studies on the reaction mechanism of a ribonuclease II from Aspergillus oryzae (author's transl)] Wikidata
Syntéza modifikovaných nukleotidů odvozených od (L-pentofuranosy) fosfonátů National Library of the Czech Republic
Syntheses of pyrimidine acyclic nucleoside phosphonates as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma. Wikidata
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds. Wikidata
Synthesis of 1-(3-deoxy-beta-D-psicofuranosyl)uracil and related compounds. Wikidata
Tenofovir diphosphate is a poor substrate and a weak inhibitor of rat DNA polymerases alpha, delta, and epsilon* Wikidata
Ternary Copper(II) Complexes in Solution Formed With 8-Aza Derivatives of the Antiviral Nucleotide Analogue 9-[2-(Phosphonomethoxy)Ethyl]Adenine (PMEA). Wikidata
Transport of 9-(2-phosphonomethoxyethyl)adenine across plasma membrane of HeLa S3 cells is protein mediated Wikidata
Transport of nucleosides in Bacillus subtilis: the effect of purine nucleosides on the cytidine-uptake Wikidata
Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine Wikidata

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