EBV gH/gL and KSHV gH/gL bind to different sites on EphA2 to trigger fusion |
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Editorial overview: Virus structure and functions |
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An Engineered Disulfide Bond Reversibly Traps the IgE-Fc3-4 in a Closed, Nonreceptor Binding Conformation |
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Ephrin receptor A4 (EphA4) is a new Kaposi's sarcoma-associated herpesvirus virus entry receptor |
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EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer-cell interfaces |
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The Epstein-Barr virus (EBV) glycoprotein B cytoplasmic C-terminal tail domain regulates the energy requirement for EBV-induced membrane fusion |
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Epstein-Barr virus fusion with epithelial cells triggered by gB is restricted by a gL glycosylation site. |
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Flexibility of the Head-Stalk Linker Domain of Paramyxovirus HN Glycoprotein Is Essential for Triggering Virus Fusion |
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Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion |
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Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel |
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Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells |
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H-IPSE is a pathogen-secreted host nucleus infiltrating protein (infiltrin) expressed exclusively by the Schistosoma haematobium egg stage. |
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HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission |
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HIV: conformational camouflage |
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Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2 |
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Hydrophobic residues that form putative fusion loops of Epstein-Barr virus glycoprotein B are critical for fusion activity |
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Identification of functionally important domains of human cytomegalovirus gO that act after trimer binding to receptors |
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The IgA receptor complex: a two-for-one deal |
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Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins |
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Inhibin α-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling |
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Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. |
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Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition |
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IPSE, a parasite-derived, host immunomodulatory infiltrin protein, alleviates resiniferatoxin-induced bladder pain |
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IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis |
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The KGD motif of Epstein-Barr virus gH/gL is bifunctional, orchestrating infection of B cells and epithelial cells |
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The large groove found in the gH/gL structure is an important functional domain for Epstein-Barr virus fusion |
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Mapping the N-terminal residues of Epstein-Barr virus gp42 that bind gH/gL by using fluorescence polarization and cell-based fusion assays |
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The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab |
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Membrane anchoring of Epstein-Barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers |
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Molecular biology of inhibin action |
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Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation |
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Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane-Proximal Stalk Region Influences Stability, Receptor Binding, and Neuraminidase Activity |
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Mutational analysis of the HLA class II interaction with Epstein-Barr virus glycoprotein 42. |
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NMEGylation: a novel modification to enhance the bioavailability of therapeutic peptides |
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De novo protein design enables the precise induction of RSV-neutralizing antibodies |
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Paramyxovirus membrane fusion: lessons from the F and HN atomic structures |
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Phylogenomic analyses reveal the evolutionary origin of the inhibin alpha-subunit, a unique TGFbeta superfamily antagonist |
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Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39. |
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Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies |
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Program review. Challenges and opportunities for training the next generation of biophysicists: perspectives of the directors of the Molecular Biophysics Training Program at Northwestern University |
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A readily applicable strategy to convert peptides to peptoid-based therapeutics |
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Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy |
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Reversible inhibition of fusion activity of a paramyxovirus fusion protein by an engineered disulfide bond in the membrane-proximal external region |
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SARS-CoV-2 Antibody Responses Correlate with Resolution of RNAemia But Are Short-Lived in Patients with Mild Illness |
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Selectivity in the post-translational, transglutaminase-dependent acylation of lysine residues. |
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Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion |
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Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions |
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Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus |
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Structural basis for a functional antagonist in the transforming growth factor beta superfamily |
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Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus |
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The structural basis of herpesvirus entry |
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Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. |
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The structural basis of TGF-beta, bone morphogenetic protein, and activin ligand binding |
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Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding |
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Structural insights into the interactions between human IgE and its high affinity receptor FcepsilonRI. |
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Structure-function studies on the bifunctional enzyme PRAI, 1986: |
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Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF- binding |
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Structure of Epstein-Barr Virus Glycoprotein 42 Suggests a Mechanism for Triggering Receptor-Activated Virus Entry |
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Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1 |
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The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding |
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Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site |
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Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation |
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Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain |
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Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein |
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The structures that underlie normal reproductive function |
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Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis. |
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A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions. |
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Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry |
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