Aaron D Gitler
Gitler, Aaron D.
VIAF ID: 556150323927809972147 (Personal)
Permalink: http://viaf.org/viaf/556150323927809972147
Preferred Forms
- 100 0 _ ‡a Aaron D Gitler
- 100 1 _ ‡a Gitler, Aaron D.
-
4xx's: Alternate Name Forms (2)
Works
Title | Sources |
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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models | |
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity | |
Analysis of COPII Vesicles Indicates a Role for the Emp47-Ssp120 Complex in Transport of Cell Surface Glycoproteins | |
ATXN2 trinucleotide repeat length correlates with risk of ALS. | |
Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1 | |
A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories | |
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity | |
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility | |
Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop | |
A cellular system that degrades misfolded proteins and protects against neurodegeneration | |
Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity | |
Congenital muscular dystrophy and generalized epilepsy caused by GMPPB mutations | |
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. | |
Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes | |
Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions | |
ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency | |
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis | |
Evidence that alpha-synuclein does not inhibit phospholipase D | |
Evolution of a Human-Specific Tandem Repeat Associated with ALS | |
Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy | |
Exome sequencing to identify de novo mutations in sporadic ALS trios | |
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. | |
GTPase activity plays a key role in the pathobiology of LRRK2. | |
High-throughput yeast plasmid overexpression screen | |
Hop is an unusual homeobox gene that modulates cardiac development | |
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models | |
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways | |
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model | |
A matter of balance | |
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS | |
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS | |
Neurodegenerative disease: models, mechanisms, and a new hope. | |
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS | |
Nf1 has an essential role in endothelial cells | |
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells. | |
Odkrywanie tajników ALS | |
Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein | |
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis | |
PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development | |
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis | |
PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats | |
Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics. | |
Regrowing axons with alternative splicing. | |
Regulating heart development: the role of Nf1. | |
The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast | |
RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats | |
Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. | |
Stress granules as crucibles of ALS pathogenesis. | |
A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae | |
Targeted exon capture and sequencing in sporadic amyotrophic lateral sclerosis | |
TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A | |
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models | |
There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS | |
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. | |
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD | |
A versatile system to record cell-cell interactions | |
A yeast functional screen predicts new candidate ALS disease genes | |
A yeast model for polyalanine-expansion aggregation and toxicity |