Ashcroft, Frances M.
![Sudoc [ABES], France](/viaf/images/flags/SUDOC.png "Sudoc [ABES], France")
Frances Ashcroft British geneticist and physiologist
Ashcroft, Frances
Ashcroft, Frances 1952-
Ashcroft, Frances (Frances M.)
Ashcroft, Frances M, 1952-
אשקרופט, פרנסס
VIAF ID: 54220244 (Personal)
Permalink: http://viaf.org/viaf/54220244
Preferred Forms
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200 _ |
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Ashcroft
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Frances M.
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100 1 _ ‡a Ashcroft, Frances
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100 1 _ ‡a Ashcroft, Frances
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100 1 _ ‡a Ashcroft, Frances M
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100 1 _
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Ashcroft, Frances M,
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1952-
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _
‡a
Ashcroft, Frances M.
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100 1 _
‡a
Ashcroft, Frances M.
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _
‡a
Ashcroft, Frances M.
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _
‡a
Ashcroft, Frances M.
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100 1 _ ‡a Ashcroft, Frances M.
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100 1 _
‡a
Ashcroft, Frances M.
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100 1 _
‡a
Ashcroft, Frances
‡d
1952-
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100 1 _ ‡a Ashcroft, Frances ‡q (Frances M.)
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200 _ 1 ‡a Ashcroft, ‡b Frances
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100 0 _
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Frances Ashcroft
‡c
British geneticist and physiologist
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100 1 _ ‡a אשקרופט, פרנסס
4xx's: Alternate Name Forms (19)
Works
| Title | Sources |
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| 3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1. |
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| An ABCC8 Nonsense Mutation Causing Neonatal Diabetes Through Altered Transcript Expression |
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| Adult onset global loss of the fto gene alters body composition and metabolism in the mouse |
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| Alexis Rockman : wonderful world. |
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| Am Limit Leben und Überleben in Extremsituationen |
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| Asymmetric switching in a homodimeric ABC transporter: a simulation study |
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| ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer |
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| Autosomal dominant hypercalciuria in a mouse model due to a mutation of the epithelial calcium channel, TRPV5 |
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| Binding of sulphonylureas to plasma proteins - A KATP channel perspective. |
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| Cardiac Dysfunction and Metabolic Inflexibility in a Mouse Model of Diabetes Without Dyslipidemia. |
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| Changes in gene expression associated with FTO overexpression in mice |
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| CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease |
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| Crystal structure of the potassium channel KirBac1.1 in the closed state |
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| Disease progression and search for monogenic diabetes among children with new onset type 1 diabetes negative for ICA, GAD- and IA-2 Antibodies |
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| Dissection-independent production of <i>Plasmodium</i> sporozoites from whole mosquitoes |
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| Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production |
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| Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity |
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| FTO demethylase activity is essential for normal bone growth and bone mineralization in mice |
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| FTO influences adipogenesis by regulating mitotic clonal expansion |
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| FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting |
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| Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes |
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| Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes. |
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| Functional identification of islet cell types by electrophysiological fingerprinting |
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| Gain-of-function mutations in the K(ATP) channel (KCNJ11) impair coordinated hand-eye tracking |
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| A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome |
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| A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes |
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| A high-throughput assay for modulators of NNT activity in permeabilized yeast cells |
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| How ATP inhibits the open K(ATP) channel |
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| Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells |
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| Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2 |
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| Influences: Find a friend |
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| Insulin, c1992: |
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| Insulin : molecular biology to pathology |
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| Introduction. The blurred boundary between channels and transporters |
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| Ion channels and disease : channelopathies |
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| Is Type 2 Diabetes a Glycogen Storage Disease of Pancreatic β Cells? |
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| The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits |
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| Life at the extremes : [the science of survival |
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| The ligand-sensitive gate of a potassium channel lies close to the selectivity filter |
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| Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane |
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| Magnesium deficiency prevents high-fat-diet-induced obesity in mice |
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| Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features |
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| Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis |
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| A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene |
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| A mutation (R826W) in nucleotide-binding domain 1 of ABCC8 reduces ATPase activity and causes transient neonatal diabetes |
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| Mutational analysis of CLC-5, cofilin and CLC-4 in patients with Dent's disease |
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| Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding |
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| Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes |
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| Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk |
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| New insights into KATP channel gene mutations and neonatal diabetes mellitus |
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| Ningen wa dokomade taerarerunoka |
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| The Nucleotide-Binding Sites of SUR1: A Mechanistic Model |
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| Nucleotide-dependent conformational changes in HisP: molecular dynamics simulations of an ABC transporter nucleotide-binding domain |
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| Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry |
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| The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase |
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| Overexpression of Fto leads to increased food intake and results in obesity |
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| Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men. |
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| Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes |
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| Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects |
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| Permanent neonatal diabetes: combining sulfonylureas with insulin may be an effective treatment |
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| Potassium channel regulation |
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| PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism |
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| Reversible changes in pancreatic islet structure and function produced by elevated blood glucose |
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| Role of the C-terminus of SUR in the differential regulation of β-cell and cardiac KATP channels by MgADP and metabolism. |
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| Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance |
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| Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels |
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| Sensibilidad diferencial a la gliclazida de los canales de Katp en células beta y extrapancreáticas |
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| The spark of life : electricity in the human body |
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| Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes. |
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| Sulfonylurea stimulation of insulin secretion |
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| Systemic Administration of Glibenclamide Fails to Achieve Therapeutic Levels in the Brain and Cerebrospinal Fluid of Rodents |
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| Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles |
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| Type 2 diabetes mellitus: not quite exciting enough? |
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| Uz izdzīvošanas robežas, 2002: |
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| A vida no limite : a ciência da sobrevivência |
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| Women in Metabolism: Part 3. |
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| Życie w warunkach ekstremalnych / Frances Ashcroft. - Warszawa, 2002 |
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| β-Cell dysfunction in diabetes: a crisis of identity? |
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| 생존의 한계 |
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| 人間はどこまで耐えられるのか |
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| 生命の閃光 : 体は電気で動いている |
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