Introduction of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression |
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Role of nitric oxide and reactive oxygen species in arthritis |
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Role of nitroso radicals as drug targets in circulatory shock |
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Role of peroxisome proliferator-activated receptor-alpha in ileum tight junction alteration in mouse model of restraint stress |
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Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion |
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Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study |
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Role of tight junction derangement in the endothelial dysfunction elicited by exogenous and endogenous peroxynitrite and poly(ADP-ribose) synthetase |
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Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury |
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Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence |
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Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury. |
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Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice |
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Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain |
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The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord |
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Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects |
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Selective CB2 inverse agonist JTE907 drives T cell differentiation towards a Treg cell phenotype and ameliorates inflammation in a mouse model of inflammatory bowel disease |
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Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. |
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Signal transduction pathways involved in protective effects of melatonin in C6 glioma cells |
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SOD mimetics are coming of age. |
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Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury |
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Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling |
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Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism |
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Sphingosine 1-phosphate receptor subtype 1 (S1PR1) as a therapeutic target for brain trauma. |
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Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat. |
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Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance |
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Splanchnic ischemia and reperfusion injury is reduced by genetic or pharmacological inhibition of TNF-α |
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Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity |
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Superoxide: a key player in hypertension |
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Superoxide, NO, peroxynitrite and PARP in circulatory shock and inflammation |
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Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine |
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Susceptibility of erythrocytes from different sources to xenobiotics-induced lysis |
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Synergic Therapeutic Potential of PEA-Um Treatment and NAAA Enzyme Silencing In the Management of Neuroinflammation |
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Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance |
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Targeting inflammation: new therapeutic approaches in chronic kidney disease (CKD). |
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Targeting selectins for the treatment of inflammatory diseases |
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Targeting the overproduction of peroxynitrite for the prevention and reversal of paclitaxel-induced neuropathic pain |
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Tempol reduces the activation of nuclear factor-kappaB in acute inflammation |
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TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney |
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Teupolioside, a phenylpropanoid glycosides of Ajuga reptans, biotechnologically produced by IRBN22 plant cell line, exerts beneficial effects on a rodent model of colitis |
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Thalidomide suppresses sclerosing encapsulating peritonitis in a rat experimental model |
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Thalidomide treatment reduces the alteration of paracellular barrier function in mice ileum during experimental colitis. |
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Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets |
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Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice |
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Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18 |
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Therapeutic potential of flavonoids in the treatment of chronic venous insufficiency |
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Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine |
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Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice |
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Thyroid hormone autoantibodies: are they a better marker to detect early thyroid damage in patients with hematologic cancers receiving tyrosine kinase inhibitor or immunoregulatory drug treatments? |
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TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas |
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TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson's diseases in vivo model |
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TLR7/8 in the Pathogenesis of Parkinson's Disease |
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TNF-alpha as a therapeutic target in acute pancreatitis--lessons from experimental models. |
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TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome |
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Topical Application of Adelmidrol + -Traumatic Acid Enhances Skin Wound Healing in a Streptozotocin-Induced Diabetic Mouse Model |
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Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model |
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Traumatic Brain Injury Leads to Development of Parkinson's Disease Related Pathology in Mice |
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Traumatic brain injury: oxidative stress and neuroprotection. |
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Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice |
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Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma |
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Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats |
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Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock |
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Tyrphostin AG 126 reduces intestinal ischemia-reperfusion injury in the rat. |
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Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase |
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UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness |
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Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat |
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Ultramicronized palmitoylethanolamide (PEA-um(®)) in the treatment of idiopathic pulmonary fibrosis. |
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Up-regulation of prostaglandin biosynthesis by leukotriene C4 in elicited mice peritoneal macrophages activated with lipopolysaccharide/interferon-{gamma}. |
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Uric acid protects against secondary damage after spinal cord injury |
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Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation |
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WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock |
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WY-14643, a Potent Peroxisome Proliferator Activator Receptor-α PPAR-α Agonist Ameliorates the Inflammatory Process Associated to Experimental Periodontitis |
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