Börries, Melanie 1971-
Melanie Boerries
VIAF ID: 55240960 ( Personal )
Permalink: http://viaf.org/viaf/55240960
Preferred Forms
- 100 1 _ ‡a Börries, Melanie ‡d 1971-
- 100 1 _ ‡a Börries, Melanie ‡d 1971-
- 100 0 _ ‡a Melanie Boerries
4xx's: Alternate Name Forms (4)
5xx's: Related Names (2)
- 510 2 _ ‡a Albert-Ludwigs-Universität Freiburg ‡b Institut für Molekulare Medizin und Zellforschung ‡4 affi ‡4 https://d-nb.info/standards/elementset/gnd#affiliation ‡e Affiliation
- 510 2 _ ‡a Tumorzentrum Freiburg - CCCF ‡4 affi ‡4 https://d-nb.info/standards/elementset/gnd#affiliation ‡e Affiliation
Works
Title | Sources |
---|---|
Combination of Lenvatinib and Pembrolizumab is an effective treatment option for anaplastic and poorly differentiated thyroid carcinoma | |
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers | |
Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity | |
Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7 | |
CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury | |
Delineating the dynamic transcriptome response of mRNA and microRNA during zebrafish heart regeneration | |
Differences in DNA methylation and functional expression in lactase persistent and non-persistent individuals | |
Dissecting the functions of EBF1 in haematopoietic progenitors and on T lymphopoiesis | |
A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS | |
Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts | |
Dysregulated PI3K signaling in B cells of CVID patients | |
Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small cell lung cancer | |
Early PSA change after [177Lu]PSMA-617 radioligand therapy as a predicator of biochemical response and overall survival | |
Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of [beta]-hemoglobinopathies | |
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1 | |
Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells | |
Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo | |
Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model | |
Expression ratio of the TGF[beta]-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response | |
Extending cBioPortal for therapy recommendation documentation in molecular tumor boards: development and usability study | |
Extrazelluläre Effekte des Ca2+-bindenden Proteins S100A1 grundlegende Experimente zur Morphologie und Funktion neonataler Kardiomyozyten in Abhängigkeit der Kulturbedingungen | |
From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract | |
Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo | |
Gene editing of hematopoietic stem cells restores T cell response in familial hemophagocytic lymphohistiocytosis | |
Genome-wide mapping of DNA-binding sites identifies stemness-related genes as directly repressed targets of SNAIL1 in colorectal cancer cells | |
Harnessing CD3 diversity to optimize CAR T cells | |
Harnessing the tissue and plasma lncRNA-peptidome to discover peptide-based cancer biomarkers | |
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures | |
HIF-1[alpha] and HIF-2[alpha] differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice | |
Identification and validation of a diagnostic and prognostic multi-gene biomarker panel for pancreatic ductal adenocarcinoma | |
Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin | |
Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer | |
Identification of the needs and preferences of patients with cancer for the development of a clinic app : qualitative study | |
Immune surveillance of acute myeloid leukemia is mediated by HLA-presented antigens on leukemia progenitor cells | |
Immunopathology caused by impaired CD8+ T‐cell responses | |
impact of pre‐pregnancy folic acid intake on placental DNA methylation in a fortified cohort | |
Impact of signaling pathways and the extracellular matrix in cancer development | |
Implementing pharmacogenomic clinical decision support into German hospitals | |
An improved organotypic cell culture system to study tissue-resident macrophages ex vivo | |
In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts | |
Individualized mini-panel sequencing of ctDNA allows tumor monitoring in complex karyotype sarcomas | |
Interferon-driven immune dysregulation in common variable immunodeficiency-associated villous atrophy and norovirus infection | |
Kindlin‐3 maintains marginal zone B cells but confines follicular B cell activation and differentiation | |
Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer | |
Lack of electron acceptors contributes to redox stress and growth arrest in asparagine-starved sarcoma cells | |
Longitudinal analysis of cell-free mutated KRAS and CA 19–9 predicts survival following curative resection of pancreatic cancer | |
Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells | |
LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL | |
Microglia modulate TNF[alpha]‐mediated synaptic plasticity | |
MIRACUM: medical informatics in research and care in university medicine : a large data sharing network to enhance translational research and medical care | |
MIRACUM-Pipe : an adaptable pipeline for next-generation <br>sequencing analysis, reporting, and visualization for clinical decision making | |
Molecular characterisation of tumours and biomarker identification for personalised radiation oncology using genomic data of patients with locally advanced head and neck squamous cell carcinoma | |
Molecular consequences of SARS-CoV-2 liver tropism | |
A multi-layered quantitative in vivo expression atlas of the podocyte unravels Kidney disease candidate genes | |
Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients | |
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma | |
Network theory inspired analysis of time-resolved expression data reveals key players guiding P. patens stem cell development | |
Non-canonical functions of SNAIL drive context-specific cancer progression | |
Non-invasive monitoring of neoadjuvant radiation therapy response in soft tissue sarcomas by multiparametric MRI and quantification of circulating tumor DNA — a study protocol | |
Noninvasive CNS lymphoma risk stratification and brain cancer classification by circulating tumor DNA profiling | |
oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma | |
Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation | |
Patient‐derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma | |
Personalized clinical decision making through implementation of a molecular tumor board: a German single-center experience | |
Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation - immune signature correlates with response | |
PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma | |
Profile of the multicenter cohort of the German Cancer Consortium’s Clinical Communication Platform | |
Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations | |
Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation | |
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification | |
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia | |
Requirements analysis and specification for a molecular tumor board platform based on cBioPortal | |
RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells | |
Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles | |
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease | |
Searching of clinical trials made easier in cBioPortal using patients' genetic and clinical profiles | |
SMAD4 mutations do not preclude epithelial–mesenchymal transition in colorectal cancer | |
SNAIL1 employs [beta]‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferation | |
SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells | |
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma | |
Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence | |
Specific role of RhoC in tumor invasion and metastasis | |
Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse | |
Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors | |
Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency | |
Systems medicine in the scope of multi omics analyses | |
T-CAST: An optimized CAST-Seq pipeline for TALEN confirms superior safety and efficacy of obligate-heterodimeric scaffolds | |
T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10 | |
Targeting of apoptotic pathways by SMAC or BH3 mimetics distinctly sensitizes paclitaxel-resistant triple negative breast cancer cells | |
TGF[beta]-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC | |
TGF[beta]1-induced EMT in the MCF10A mammary epithelial cell line model is executed independently of SNAIL1 and ZEB1 but relies on JUNB-coordinated transcriptional regulation | |
Therapeutic effects of inhibition of sphingosine-1-phosphate signaling in HIF-2[alpha] inhibitor-resistant clear cell renal cell carcinoma | |
Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease | |
Transcriptome dynamics to unravel PC12 cell fate decisions | |
USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING | |
Variable outcome of immunotherapy in advanced multiple cutaneous squamous cell carcinomas in two patients with recessive dystrophic epidermolysis bullosa | |
ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma |