Juan C. Laguna researcher
Laguna Egea, Juan Carlos
VIAF ID: 305873145 (Personal)
Permalink: http://viaf.org/viaf/305873145
Preferred Forms
- 100 0 _ ‡a Juan C. Laguna ‡c researcher
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4xx's: Alternate Name Forms (4)
Works
Title | Sources |
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Acción farmacológica a nivel hepático de los derivados polifenólicos de Cynara scolymus L. | |
Acción in vitro del ácido clofíbrico y derivados sobre enzimas lipogénicos en higado de rata | |
The Addition of Liquid Fructose to a Western-Type Diet in LDL-R-/- Mice Induces Liver Inflammation and Fibrogenesis Markers without Disrupting Insulin Receptor Signalling after an Insulin Challenge | |
Alteraciones metabólicas inducidas por la edad : modificación de la expresión de PPAR[alpha] y de la respuesta farmacológica | |
Caracterització molecular de les alteracions en el metabolisme lipídic hepàtic induïdes per la fructosa en rata : paper de la leptina | |
Control de la producció hepàtica de VLDL per estatines i fibrats | |
Differential inhibition of long-chain acyl-CoA hydrolases by hypolipidemic drugs in vitro. | |
Down-regulation of acyl-CoA oxidase gene expression in heart of troglitazone-treated mice through a mechanism involving chicken ovalbumin upstream promoter transcription factor II. | |
Efectes metabòlics, vasculars i cognitius del consum de sucres simples en rates femella | |
Efecto in vivo de los derivados fíbricos sobre enzimas microsomales implicados en la síntesis hepática de ácidos grasos | |
Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation | |
Effects of rosiglitazone and atorvastatin on the expression of genes that control cholesterol homeostasis in differentiating monocytes | |
[Emergency care of patients with upper gastrointestinal bleeding in regional hospitals in Catalonia] | |
Etomoxir, Sodium 2-[6-(4-Chlorophenoxy)hexyl]oxirane-2-carboxylate, Up-Regulates Uncoupling Protein-3 mRNA Levels in Primary Culture of Rat Preadipocytes | |
Factores implicados en la respuesta diferencial a proliferadores peroxisómicos entre células hepáticas de rata y humanas : modulación de la expresión de la SCD 1 | |
Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients | |
Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues | |
Fructose during pregnancy provokes fetal oxidative stress: The key role of the placental heme oxygenase-1. | |
Fructose only in pregnancy provokes hyperinsulinemia, hypoadiponectinemia, and impaired insulin signaling in adult male, but not female, progeny. | |
Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress. | |
Gemfibrozil increases the specific binding of rat-cortex nuclear extracts to a PPRE probe | |
Hepatoprotective activity of polyphenolic compounds from Cynara scolymus against CCl4 toxicity in isolated rat hepatocytes | |
Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake | |
Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice | |
Hypertriglyceridemia and hepatic steatosis in senescence-accelerated mouse associate to changes in lipid-related gene expression. | |
Identificación y caracterización de genes regulados por NOR-1 (Neuron-derived Orphan Receptor-1) implicación en el remodelado vascular y la diferenciación celular | |
Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone | |
In vitro effect of clofibric acid derivatives on rat hepatic microsomal electron transport chains | |
Increased Akt protein expression is associated with decreased ceramide content in skeletal muscle of troglitazone-treated mice | |
Influence of lipid profile and fatty acid composition on the oxidation behavior of rat and guinea pig low density lipoprotein. | |
Ingesta de fructosa líquida, fetge gras i intolerància a la glucosa | |
Intervención dietética en la hipercolesterolemia tipo IIa poligénica : efectos de una dieta enriquecida en nueces : the Barcelona walnut trial | |
Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha | |
Lipoprotein composition and oxidative modification during therapy with gemfibrozil and lovastatin in patients with combined hyperlipidaemia. | |
Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats | |
Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells. | |
Liquid fructose in pregnancy exacerbates fructose-induced dyslipidemia in adult female offspring. | |
Liquid fructose in Western-diet-fed mice impairs liver insulin signaling and causes cholesterol and triglyceride loading without changing calorie intake and body weight | |
Liquid fructose supplementation in LDL-R−/− mice fed a western-type diet enhances lipid burden and atherosclerosis despite identical calorie consumption | |
Liver AMP/ATP ratio and fructokinase expression are related to gender differences in AMPK activity and glucose intolerance in rats ingesting liquid fructose. | |
Mecanismos moleculares implicados en las alteraciones metabólicas inducidas por la suplementación subcrónica de fructosa líquida : estrés de retículo, autofagia y resistencia a la insulina | |
Metabolic alterations and increased liver mTOR expression precede the development of autoimmune disease in a murine model of lupus erythematosus | |
Modificació de l'activitat lipogènica en rata per tractament semicrònic amb fibrats | |
Modificación de la composición cualitativa de los ácidos grasos en fosfolípidos microsomales hepáticos de rata por la administración de fibratos | |
Modulació de l'expressió de la SCD1 per fibrats en cèl·lules d'hepatoma humà | |
Monocyte gene-expression profile in men with familial combined hyperlipidemia and its modification by atorvastatin treatment | |
Neovascularización mediada por factor tisular en la placa aterosclerótica | |
Noves aportacions al coneixement i la prevenció de la inflamació i la resistència a la insulina induïdes per àcids grassos en cèl·lules musculars esquelètiques | |
Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy | |
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells | |
Opposite fates of fructose in the development of metabolic syndrome | |
Oxidation of low-density lipoproteins in renal transplant recipients treated with tacrolimus. | |
The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells. | |
Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation | |
Peroxisome proliferator-activated receptor alpha down-regulation is associated with enhanced ceramide levels in age-associated cardiac hypertrophy | |
PGC-1beta down-regulation is associated with reduced ERRalpha activity and MCAD expression in skeletal muscle of senescence-accelerated mice. | |
Phenotyping of sigma-1 receptor knock-out rodents | |
Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs | |
Randomized crossover study of gemfibrozil versus lovastatin in familial combined hyperlipidemia: additive effects of combination treatment on lipid regulation. | |
Reduction of intracellular cholesterol accumulation in THP-1 macrophages by a combination of rosiglitazone and atorvastatin | |
Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment | |
Reductions in plasma cholesterol levels after fenofibrate treatment are negatively correlated with resistin expression in human adipose tissue. | |
Regulació per bezafibrat de l'expressió de gens implicats en el metabolisme lipídic en la rata | |
Regulation of gene expression in atherosclerosis: insights from microarray studies in monocytes/macrophages | |
Relationship between plasma lipids and palmitoyl-CoA hydrolase and synthetase activities with peroxisomal proliferation in rats treated with fibrates. | |
Ritonavir increases CD36, ABCA1 and CYP27 expression in THP-1 macrophages | |
Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism | |
Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation | |
Sexual dimorphism in lipid metabolic phenotype associated with old age in Sprague–Dawley rats | |
Simple sugar intake and hepatocellular carcinoma: epidemiological and mechanistic insight | |
Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. | |
Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism | |
Terapia hipolemiante en pacientes tipo IIb : efecto sobre la composición y oxidabilidad de las lipoproteínas plasmáticas | |
Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages | |
TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model | |
Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions | |
Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats | |
Validación de dianas farmacológicas para la prevención y el tratamiento de la hipertrigliceridemia y el hígado graso inducidos por el consumo de fructosa líquida y dieta rica en grasa saturada | |
Valoración de fármacos antiinflamatorios in vivo | |
Way back for fructose and liver metabolism: bench side to molecular insights |