The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis |
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Meal rich in carbohydrate, but not protein or fat, reveals adverse immunometabolic responses associated with obesity |
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Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function |
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Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility |
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The metabolic profile of early Huntington's disease--a combined human and transgenic mouse study |
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Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet |
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Methods for performing lipidomics in white adipose tissue |
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Mice expressing human but not murine beta3-adrenergic receptors under the control of human gene regulatory elements. |
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Mild cold effects on hunger, food intake, satiety and skin temperature in humans. |
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Mitochondria are required for pro-ageing features of the senescent phenotype. |
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The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. |
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Monounsaturated fat-rich diet prevents central body fat distribution and decreases postprandial adiponectin expression induced by a carbohydrate-rich diet in insulin-resistant subjects |
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Mouse models of PPAR-gamma deficiency: dissecting PPAR-gamma's role in metabolic homoeostasis. |
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Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase |
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No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits |
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Nothing Iffy about HIF in the Hypothalamus. |
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Nuclear receptor corepressor RIP140 regulates fat accumulation |
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The obese healthy paradox: is inflammation the answer? |
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Obesity and diabetes: an avalanche of new information |
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"Obesity associated metabolic complications, the second wave of the tsunami" 14 Key Symposium |
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[Obesity, MODY and juvenile diabetes: a new diagnostic challenge] |
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Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. |
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Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation |
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Orexin expression is regulated by alpha-melanocyte-stimulating hormone |
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The organization, promoter analysis, and expression of the human PPARgamma gene |
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Origins of metabolic complications in obesity: ectopic fat accumulation. The importance of the qualitative aspect of lipotoxicity |
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P465L-PPARγ mutation confers partial resistance to the hypolipidaemic action of fibrates |
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Pathways to the analysis of microarray data |
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Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis. |
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The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro |
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Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility |
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PGC-1α negatively regulates extrasynaptic NMDAR activity and excitotoxicity |
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Pharmacological strategies for targeting BAT thermogenesis. |
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Phenyl-γ-valerolactones, flavan-3-ol colonic metabolites, protect brown adipocytes from oxidative stress without affecting their differentiation or function. |
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Physiology: Immune cells fuel the fire. |
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Postprandial inflammatory response in adipose tissue of patients with metabolic syndrome after the intake of different dietary models |
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PPARgamma and the thiazolidinediones: molecular basis for a treatment of 'Syndrome X'? |
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PPARs and Metabolic Disorders Associated with Challenged Adipose Tissue Plasticity |
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Prediction of weight loss and regain following dietary, lifestyle, and pharmacologic intervention. |
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A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice |
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Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans. |
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Protein CoAlation: a redox-regulated protein modification by coenzyme A in mammalian cells. |
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Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome |
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Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists |
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Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha. |
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Regulation of glucose homoeostasis by brown adipose tissue. |
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Regulation of mitochondrial morphology and function by stearoylation of TFR1. |
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Regulation of PPAR gamma gene expression by nutrition and obesity in rodents. |
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Reply to: 'Browning capabilities of human primary adipose-derived stromal cells compared to SGBS cells' |
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Response to letter regarding article, "Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans". |
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Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice |
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A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction |
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Role of PPARγ in adipocyte recruitment and thermogenesis |
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Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis. |
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Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity. |
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A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations |
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Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition |
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SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes. |
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A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. |
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Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans |
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Special issue on lipotoxicity |
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Sphingolipids and glycerophospholipids - The "ying and yang" of lipotoxicity in metabolic diseases. |
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SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation |
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Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes |
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The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production |
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Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis |
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Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic mice. |
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Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. |
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Targeting fat to prevent diabetes |
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Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation. |
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Thyroid hormones directly activate the expression of the human and mouse uncoupling protein-3 genes through a thyroid response element in the proximal promoter region |
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Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis |
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Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis |
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Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression. |
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Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose Tissue |
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UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue |
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UCPs--unlikely calcium porters. |
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Uncoupling expectations |
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Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria. |
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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. |
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Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism. |
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Understanding disease mechanisms with models of signaling pathway activities. |
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Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet. |
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An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity |
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Using brown adipose tissue to treat obesity - the central issue. |
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Visceral fat accumulation during lipid overfeeding is related to subcutaneous adipose tissue characteristics in healthy men |
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When BAT is lacking, WAT steps up. |
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The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis. |
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Wnt signalling and the control of cellular metabolism. |
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WNT10B mutations in human obesity. |
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β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development |
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