ANALYSE DES REPERTOIRES AUTOREACTIFS DES ANTICORPS NATURELS CHEZ L'HOMME SAIN ET AU COURS DE PATHOLOGIES DYSIMMUNITAIRES |
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ANALYSIS OF SELF-REACTIVE REPERTOIRES OF NATURAL ANTIBODIES IN HEALTHY HUMAN AND DURING DYSIMMUNE DISEASES. |
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Anti-HLA antibodies in antibody-mediated rejection : role of IgG subclasses distribution and glycosylation. |
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Les anticorps anti-HLA au cours du rejet à médiation humorale : rôle de la sous-classe et de la glycosylation des anticorps |
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Anticorps catalytiques dirigés contre le FVIII dans différentes maladies chez l'homme |
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Caractérisation des mécanismes de présentation des antigènes par les molécules du CMH-II |
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Catalytic antibodies directed against factor VIII in different human disorders. |
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Characterization of MHC-II-restricted antigen presentation mechanisms. |
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Control of the immune response directed against the therapeutic factor FVIII. |
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Creating and Use of an New Experimental Preclinical HLA Transgenic Mice Model to Mapping HLA-restricted T Cells Epitopes for Polyepitopes Vaccine Design |
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Deciphering the early events leading to an adaptive immune response during urinary tract infection. |
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Définir le début des événements conduisant à une réponse immunitaire adaptative lors de l'infection urinaire |
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Eradication des inhibiteurs du FVIII chez les patients atteints d'hémophilie A. |
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Étude de l'implication de l'activateur tissulaire du plasminogène dans la réponse immunitaire |
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Exploitation d’un modèle expérimentale préclinique de souris HLA transgénique pour l’identification des épitopes T HLA-restreint afin de concevoir des vaccins poly-epitopiques. |
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A high-throughput selection system to quantify the specificity of antibodies |
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Identification des épitopes T d'ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique |
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Immunogénicité du facteur VIII thérapeutique : importance du complément et des domaines C du facteur VIII pour son endocytose |
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Impact de l'IL-1β sur les lymphocytes Tfh et Tfr dans la réaction de centre germinatif physiologique et pathologique. |
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Influence of the polyreactivity natural and led by the soluble immunoglobulins and the receivers of lymphocytes B on the modulation of the immune response. |
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The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status |
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Intravenous immunoglobulin in neurological disorders: a mechanistic perspective |
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IVIg treatment reduces catalytic antibody titers of renal transplanted patients |
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Modulation of human dendritic cell maturation and function by natural IgG antibodies |
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Natural autoantibodies: immune homeostasis and therapeutic intervention |
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Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells. |
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Natural recognition repertoire and the evolutionary emergence of the combinatorial immune system |
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Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody |
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Noncanonical Functions of Antibodies |
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Novel cellular and molecular mechanisms of induction of immune responses by aluminum adjuvants |
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Novel therapeutic strategies for multiple sclerosis: potential of intravenous immunoglobulin |
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Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A. |
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Parameters that influence the prediction of epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnosis |
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Pathophysiology of inhibitors to factor VIII in patients with haemophilia A. |
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Peptide decoys selected by phage display block in vitro and in vivo activity of a human anti-FVIII inhibitor. |
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Physiopathology of catalytic antibodies: the case for factor VIII-hydrolyzing immunoglobulin G. |
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Polyreactivity of disease-associated anti-RBC IgG autoantibodies of patients with warm autoimmune haemolytic anaemia and natural anti-RBC IgG autoantibodies of healthy individuals |
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Predictive immunogenicity of Refacto AF. |
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Prevalence and gene characteristics of antibodies with cofactor-induced HIV-1 specificity. |
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Proteolytic antibodies activate factor IX in patients with acquired hemophilia. |
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Receptor of endocytosis for factor VIII by antigen presenting cells and role in the initiation of anti factor VIII immune response |
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Red blood cell transfusions are associated with alterations in self-reactive antibody repertoires of plasma IgM and IgG, independent of the presence of a specific immune response toward RBC antigens |
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[Regulation of autoreactivity by the idiotypic network and therapeutic modulation of autoimmunity by polyvalent intravenous immunoglobulins (IgIV)] |
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Relationship between natural and heme-mediated antibody polyreactivity. |
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Rôle de l'environnement inflammatoire dans l'immunogénicité du facteur VIII thérapeutique chez les patients hémophiles A |
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A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytes |
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Role of the intrinsic coagulation pathway in atherogenesis assessed in hemophilic apolipoprotein E knockout mice |
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The role of VWF in the immunogenicity of FVIII. |
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Rôle physiopathologique des anticorps catalytiques et des anticorps polyréactifs |
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Selective impairment of serum antibody repertoires toward muscle and thymus antigens in patients with seronegative and seropositive myasthenia gravis |
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The self-reactive antibody repertoire of normal human serum IgM is acquired in early childhood and remains conserved throughout life |
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Sialylation may be dispensable for reciprocal modulation of helper T cells by intravenous immunoglobulin. |
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Les signaux de danger dans l'initiation de la réponse immunitaire contre le facteur VIII thérapeutique |
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Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium |
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Study of the implication of tissue-type plasminogen receptor in immune response. |
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Study of the response of human hormone H2-relaxin-specific T-cells and non-natural modifications : perspectives for the reduction of the immunogenicity of therapeutic proteins and peptides. |
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Summary report of the First International Conference on inhibitors in haemophilia A. |
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Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications. |
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T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes. |
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Therapeutic factor VIII does not trigger TLR1.2 and TLR2.6 signalling in vitro. |
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Therapeutic strategies against FVIII immune response in hemophilia A : by modifying FVIII structure, by inhibiting B cells signalisation. |
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Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor. |
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Thermodynamic stability contributes to immunoglobulin specificity |
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Transfert materno-foetal de protéines thérapeutiques par des IgGs modifiées et induction de tolérance immunitaire |
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Transition towards antigen-binding promiscuity of a monospecific antibody |
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Transplacental delivery of therapeutic proteins mediated by engineered IgGs and tolerance induction. |
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[Use of intravenous polyclonal immunoglobulins in autoimmune and inflammatory disorders]. |
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Vers le développement d'une thérapie génique pour la maladie de Pompe : Caractérisation du phénotype immunitaire de la maladie de Pompe et comparaison du potentiel thérapeutique de la thérapie génique avec le traitement standard actuel. |
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VWF protects FVIII from endocytosis by dendritic cells and subsequent presentation to immune effectors. |
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