CONTROLE PHARMACOGENETIQUE DE LA REPONSE IMMUNITAIRE PAR DESTRUCTION SELECTIVE DES LYMPHOCYTES T ACTIVES EXPRIMANT UN GENE SUICIDE SOUS CONTROLE DE SEQUENCES REGULATRICES DU GENE CD4 |
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CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations. |
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La cytométrie en flux |
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La désintégrine et métalloprotéinase à motifs thrombospondines de type 4 : implications dans la régénération axonale, la myélinisation et la fibrinolyse |
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Development of an advanced therapy medicinal product using stromal vascular fraction of autologous adipose tissue in systemic scleroderma : from biological characterization to identification of potential biomarkers of efficacy. |
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Développement et fonction des lymphocytes T régulateurs : rôle du corécepteur CD4, du G-CSF et des anti-TNF |
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Effects of an enteral glucose supply on protein synthesis, proteolytic pathways, and proteome in human duodenal mucosa |
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Efficiency of laryngeal motor nerve repair is greater with bulbar than with mucosal olfactory ensheathing cells. |
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Étude physiopathologique de la myopathie auto-immune des souris NOD invalidées pour la voie de costimulation ICOS/ICOSL. |
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Étude rétrospective comparant cyclophosphamide versus rituximab aux cours des pneumopathies interstitielles associées aux myopathies inflammatoires |
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Evaluation des effets thérapeutiques de neuropeptides contre la sclérose en plaques : les orexines, le vasoactive intestinal peptide, le pituitary adenylate cyclase-activating polypeptide et leurs analogues |
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Évaluation in vivo de molécules biologiques mono ou bi-spécifiques dérivées des anticorps monocaténaires de lama (nanobodies) : étude portant sur leurs capacités à moduler les activités biologiques ou à induire la déplétion cellulaire |
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Exploration des mécanismes inflammatoires impliqués dans la physiopathologie de la maladie de Fabry et la réponse à l'enzymothérapie substitutive |
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Extent of tumor-brain interface: a new tool to predict evolution of malignant gliomas. |
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Facteurs de risque de rechute précoce chez des patients atteints de pemphigus traités par rituximab en première ligne |
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Facteurs du complément et microangiopathie thrombotique rénale : à propos de 57 observations |
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La Faculté de médecine et pharmacie de Rouen |
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Fiabilité des immunodots commerciaux dans le diagnostic des syndromes neurologiques paranéoplasiques |
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Functional Tolerance of CD8+ T Cells Induced by Muscle-Specific Antigen Expression |
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Gene profiling predicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra) |
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Gene therapy for HIV: from myth to reality? |
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Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer |
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Genetic basis and molecular mechanisms of pediatric Evans syndrome. |
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[Heterogeneity and function of human B lymphocytes]. |
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High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody. |
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Identification of 7 Proteins in Sera of RA Patients with Potential to Predict ETA/MTX Treatment Response. |
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Identification of S100A9 as biomarker of responsiveness to the methotrexate/etanercept combination in rheumatoid arthritis using a proteomic approach |
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The IgG2 Isotype of Anti-Transcription Intermediary Factor 1γ Autoantibodies Is a Biomarker of Cancer and Mortality in Adult Dermatomyositis |
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Immune-mediated necrotizing myopathy: clinical features and pathogenesis |
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Immunological defects after suicide gene therapy of experimental graft-versus-host disease. |
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In situ gene transfer into animal tendons by injection of naked DNA and electrotransfer |
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In vivo evaluation of mono- and bispecific biologics derived from single-chain antibodies from camelids (nanobodies) : a study on their ability to modulate biological activities or to induce cell depletion.. |
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Induction of Hematopoietic Microchimerism by Gene-Modified BMT Elicits Antigen-Specific B and T Cell Unresponsiveness toward Gene Therapy Products |
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Inflammatory mechanisms involved in the pathophysiology of Fabry disease and the clinical response to enzyme replacement therapy. |
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Inhibition des réponses immunitaires induites après transfert de gène par vecteur AAV recombinant : preuve de concept de l'efficacité prophylactique de la tolérisation orale dans un modèle murin |
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Intérêt des cellules gliales olfactives provenant de la muqueuse olfactive pour la réhabilitation des lésions du système nerveux moteur périphérique et central |
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INTERET DU RAPPORT DES ISOENZYMES DE LA LACTATE DESHYDROGENASE LDH5/LDH2 ET DE LA GAMMA-GLUTAMYL TRANSPEPTIDASE DANS LA SURVEILLANCE POSTOPERATOIRE PRECOCE DES TRANSPLANTATIONS HEPATIQUES EN PEDIATRIE |
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Intrasinusoidal cytotoxic CD8+ T cells in nodular regenerative hyperplasia of the liver |
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Isolation, characterization, and genetic profiling of subpopulations of olfactory ensheathing cells from the olfactory bulb |
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Lactate dehydrogenase isoenzyme LD5/LD2 ratio as an indicator of early graft function and complications following pediatric orthotopic liver transplantation |
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The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation |
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Long-term outcome of patients with polymyositis/ dermatomyositis and anti-PM-Scl antibody |
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Marked efficacy of a therapeutic strategy associating prednisone and plasma exchange followed by rituximab in two patients with refractory myopathy associated with antibodies to the signal recognition particle (SRP) |
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Mécanismes contrôlant la tolérance immunologique vis-à-vis des auto-antigènes exprimés par le muscle squelettique |
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Muscle resident macrophages control immune cell reaction to myoinjury.. |
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Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model |
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Néphropathie à BK virus et rejet aigu cellulaire : étude morphologique et analyse immunophénotypique de l'infiltrat inflammatoire |
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Newborn- and adult-derived brain microvascular endothelial cells show age-related differences in phenotype and glutamate-evoked protease release |
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Nouvelles stratégies vaccinales anti-tumorales par vecteurs AAVs recombinants : manipulation de la mort cellulaire immunogénique dans le contexte tumoral |
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Number and phenotype of rheumatoid arthritis patients' CD4+CD25hi regulatory T cells are not affected by adalimumab or etanercept |
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Paraneoplastic dermatomyositis : role of anti-TIF1gamma antibodies and cancer in triggering dermatomyositis. |
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Pathogenic role of anti-signal recognition protein and anti-3-Hydroxy-3-methylglutaryl-CoA reductase antibodies in necrotizing myopathies: Myofiber atrophy and impairment of muscle regeneration in necrotizing autoimmune myopathies. |
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Pathogénicité des auto-anticorps anti-SRP et anti-HMGCR au cours des myopathies nécrosantes auto-immunes |
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A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma |
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Physiopathological study of autoimmune myopathy in disabled NOD mice for the ICOS/ICOSL costimulation pathway. |
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Position-dependent variegation of a CD4 minigene with targeted expression to mature CD4+ T cells. |
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Potential of olfactory ensheathing cells from different sources for spinal cord repair |
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Predominance of type 1 (Th1) cytokine production in the liver of patients with HCV-associated mixed cryoglobulinemia vasculitis. |
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Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes |
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Prolonged allograft survival through conditional and specific ablation of alloreactive T cells expressing a suicide gene |
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Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model |
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Rapid screening of cryopreservation protocols for murine prepubertal testicular tissue by histology and PCNA immunostaining |
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Reduced Frequency of Regulatory T Cells in Peripheral Blood Stem Cell Compared to Bone Marrow Transplantations |
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Retrovirus-mediated gene transfer into T cells: 95% transduction efficiency without further in vitro selection |
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Rôle des auto-anticorps et des molécules du CMH de classe I dans la physiopathologie des myopathies inflammatoires |
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The role of CD4+CD25hi regulatory T cells in the physiopathogeny of graft-versus-host disease. |
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Serum levels of anti-SRP54 antibodies reflect disease activity of necrotizing myopathy in a child treated effectively with combinatorial methylprednisolone pulses and plasma exchanges followed by intravenous cyclophosphamide |
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Shared blood and muscle CD8+ T-cell expansions in inclusion body myositis |
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Single domain antibodies: promising experimental and therapeutic tools in infection and immunity |
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Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function |
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Statin-related inflammatory myopathy |
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T cell repertoire in patients with stable scleroderma |
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Therapeutic effects of VIP, PACAP, orexins and their analogs in experimental models of multiple sclerosis. |
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Thèse confidentielle |
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Transient control of a virus-induced immunopathology by genetic immunosuppression. |
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Transplantation of olfactory ensheathing cells promotes axonal regeneration and functional recovery of peripheral nerve lesion in rats |
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Troubles de l'humeur et auto-immunité : illustration à travers deux cas cliniques |
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Tuning IL-2 signaling by ADP-ribosylation of CD25. |
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Usefulness of monitoring of B cell depletion in rituximab-treated rheumatoid arthritis patients in order to predict clinical relapse: a prospective observational study. |
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Valeur pronostique d’un test permettant la détection des DSA capables de fixer le C3d au moment du diagnostic de rejet humoral chez des transplantés rénaux |
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Value of magnetic resonance imaging for evaluating muscle inflammation: insights from a new mouse model of myositis |
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Would suicide gene therapy solve the 'T-cell dilemma' of allogeneic bone marrow transplantation? |
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