John W. Semple
Semple, John W.
VIAF ID: 121921979 (Personal)
Permalink: http://viaf.org/viaf/121921979
Preferred Forms
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John W. Semple
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Semple
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John W.
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Semple, John W.
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Semple, John W.
4xx's: Alternate Name Forms (3)
Works
| Title | Sources |
|---|---|
| Flow cytometric analysis of platelets from children with the Wiskott-Aldrich syndrome reveals defects in platelet development, activation and structure |
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| Immunoglobulin therapy |
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| The immunopathogenesis of immune thrombocytopenia: T cells still take center-stage |
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| In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies |
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| Indirect allorecognition of platelets by T helper cells during platelet transfusions correlates with anti-major histocompatibility complex antibody and cytotoxic T lymphocyte formation |
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| Induction of a secondary human anti-HLA alloimmune response in severe combined immunodeficient mice engrafted with human lymphocytes |
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| Influence of antigen processing on immune responsiveness |
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| Inhibition of xenogeneic GVHD by PEN110 treatment of donor human PBMNCs. |
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| Intravenous immunoglobulin prevents murine antibody-mediated acute lung injury at the level of neutrophil reactive oxygen species (ROS) production |
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| ITP: a new regulatory issue! |
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| ITP has elevated BAFF expression |
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| ITP three R's: regulation, routing, rituximab |
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| IVIG induces dose-dependent amelioration of ITP in rodent models |
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| IVIg inhibits reticuloendothelial system function and ameliorates murine passive-immune thrombocytopenia independent of anti-idiotype reactivity. |
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| Leukoreduction just doesn't "take away" immunogenic leukcocytes, it creates an immunosuppressive leukocyte dose. |
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| Management of immune thrombocytopenic purpura in children: potential role of novel agents |
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| Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets |
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| Mechanisms and therapeutic prospects of thrombopoietin receptor agonists |
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| Megakaryocytes listen for their progeny's progeny during inflammation |
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| Microparticles as biomarkers of lung disease: enumeration in biological fluids using lipid bilayer microspheres |
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| Move over Tregs, MDSCs are here |
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| Moving target PF4 directs HIT responses |
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| Naturally processed heterodimeric disulfide-linked insulin peptides bind to major histocompatibility class II molecules on thymic epithelial cells |
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| New Emerging Developments of Platelets in Transfusion Medicine |
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| The nonhemostatic immune functions of platelets. |
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| Nouvelle cuisine: platelets served with inflammation |
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| A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells |
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| A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy |
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| Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) |
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| Plasma-derived biological medicines used to promote haemostasis |
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| Platelet and immune responses to oral cyclic dexamethasone therapy in childhood chronic immune thrombocytopenic purpura |
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| Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells |
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| Platelet antigen-induced regulation in ITP |
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| Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets |
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| Platelet GPIb-IX has suppressive effects on septic inflammation |
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| Platelet immunobiology: platelets as prey and predator |
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| Platelet-surface glycoproteins in healthy and preeclamptic mothers and their newborn infants |
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| Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo |
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| Platelets and the immune continuum |
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| Platelets deliver small packages of genetic function |
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| Platelets give us many messages |
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| Platelets play a direct role in sepsis-associated endothelial cell death |
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| Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation |
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| Preanalytical requirements for flow cytometric evaluation of platelet activation: choice of anticoagulant |
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| Processed platelet HPA1a peptides au naturel |
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| Processing and presentation of insulin. II. Evidence for intracellular, plasma membrane-associated and extracellular degradation of human insulin by antigen-presenting B cells |
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| Processing and presentation of insulin. III. Insulin degrading enzyme: a neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells |
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| Quality of thrombin produced from the patient's own plasma using the TPD, a new Thrombin-processing Device. |
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| Quantification of platelet activation status by analyzing P-selectin expression |
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| Rapid separation of CD4+ and CD19+ lymphocyte populations from human peripheral blood by a magnetic activated cell sorter (MACS) |
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| Recipient humoral immunity against leukoreduced allogeneic platelets is suppressed by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase |
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| A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg? |
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| Single nucleotide polymorphism (SNP) analysis demonstrates a significant association of tumour necrosis factor-alpha (TNFA) with primary immune thrombocytopenia among Caucasian adults |
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| The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia |
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| Splenic lymphocyte subtypes in immune thrombocytopenia: increased presence of a subtype of B-regulatory cells |
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| Sulfated beef insulin treatment elicits CD8+ T cells that may abrogate immunologic insulin resistance in type I diabetes |
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| T cell and cytokine abnormalities in patients with autoimmune thrombocytopenic purpura |
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| T granules in human platelets function in TLR9 organization and signaling |
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| Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP) |
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| Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia |
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| Transfusion-associated circulatory overload |
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| Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model. |
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| Transfusion-related immunomodulation by platelets is dependent on their expression of MHC Class I molecules and is independent of white cells |
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| Treating murine inflammatory diseases with an anti-erythrocyte antibody |
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| The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation |
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| Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens |
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| Update on the pathophysiology of transfusion-related acute lung injury |
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