Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells |
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Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner. |
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Bombesin-induced pancreatic regeneration in pigs is mediated by p46Shc/p52Shc and p42/p44 mitogen-activated protein kinase upregulation. |
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c-Cbl tyrosine phosphorylation and subcellular localization in human primary leukemic cells |
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Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein |
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The CHD4 NuRD complex links epigenetics to glycolytic flux and proliferation of melanoma and a variety of cancer cells |
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The chromodomain helicase CHD4 regulates ERBB2 signaling pathway and autophagy in ERBB2 breast cancer cells |
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Ciblage des ARNs long non codants dans le cancer humain : application au mélanome et au carcinome rénal à cellules claires. |
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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis |
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Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs |
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Early differential molecular response of a macrophage cell line to yeast and hyphal forms of Candida albicans |
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Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells |
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Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells |
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Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1 |
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In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer. |
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In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype. |
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Interrogating open issues in cancer precision medicine with patient-derived xenografts. |
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Investigating the metastatic niche in melanoma: a new therapeutic opportunity? |
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The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential. |
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Loss of amplification and appearance of a novel translocation site of the c-myc oncogene in HL-60 leukemia cells |
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Melanoma: targeting signaling pathways and RaLP |
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Modeling cell proliferation in human acute myeloid leukemia xenografts |
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Molecular networks in melanoma invasion and metastasis. |
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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction |
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Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway. |
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p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells |
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p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value |
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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. |
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p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells. |
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Pirin inhibits cellular senescence in melanocytic cells. |
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Retroviral gene transfer, rapid selection, and maintenance of the immature phenotype in mouse dendritic cells |
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The RIalpha subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor |
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RNAi screens identify CHD4 as an essential gene in breast cancer growth |
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Salicylates inhibit T cell adhesion on endothelium under nonstatic conditions: induction of L-selectin shedding by a tyrosine kinase-dependent mechanism |
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ShcD Binds DOCK4, Promotes Ameboid Motility and Metastasis Dissemination, Predicting Poor Prognosis in Melanoma |
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Structural and functional organization of the HF.10 human zinc finger gene (ZNF35) located on chromosome 3p21-p22 |
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Suppressor macrophages in tumor-bearing mice. Inconsistency betweenin vivo andin vitro findings? |
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Targeting lncRNAs in human cancer : insights into melanoma and clear cell renal cell carcinoma |
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Tbx3 represses E-cadherin expression and enhances melanoma invasiveness. |
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Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth |
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Tyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activation |
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Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism to control vascular endothelial growth factor receptor-2 signaling |
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WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells |
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