Andrew P Halestrap investigador
Halestrap, Andrew P., 19..-....
![Sudoc [ABES], France](/viaf/images/flags/SUDOC.png "Sudoc [ABES], France")
VIAF ID: 100472017 (Personal)
Permalink: http://viaf.org/viaf/100472017
Preferred Forms
4xx's: Alternate Name Forms (4)
Works
| Title | Sources |
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| Hypoxie et métabolisme tumoral : analyse génétique et fonctionnelle des symporteurs H+/lactate et de leur chaperone, BASIGINE |
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| The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein |
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| Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots |
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| Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content |
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| Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health |
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| Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria |
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| Measurement of the intramitochondrial volume in hepatocytes without cell disruption and its elevation by hormones and valinomycin |
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| The mechanism of action of FK 506. |
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| The mechanisms by which mild respiratory chain inhibitors inhibit hepatic gluconeogenesis |
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| Mitochondria: a target for myocardial protection. |
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| Mitochondria and cell death: a pore way to die? |
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| Mitochondrial calcium in health and disease |
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| Mitochondrial 'flashes': a radical concept repHined. |
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| The mitochondrial K(ATP) channel--fact or fiction? |
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| Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion |
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| The mitochondrial pyruvate carrier: has it been unearthed at last? |
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| The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors |
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| The 'mitoflash' probe cpYFP does not respond to superoxide |
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| N-terminal protein sequence analysis of the rabbit erythrocyte lactate transporter suggests identity with the cloned monocarboxylate transport protein MCT1. |
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| The nature of the stimulation of the respiratory chain of rat liver mitochondria by glucagon pretreatment of animals |
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| The neuroplastin adhesion molecules are accessory proteins that chaperone the monocarboxylate transporter MCT2 to the neuronal cell surface |
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| Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms |
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| The pathway of electron flow through ubiquinol:cytochrome c oxidoreductase in the respiratory chain. Evidence from inhibition studies for a modified ‘Q cycle’ |
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| Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells |
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| The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. |
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| Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass |
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| Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts. |
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| Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin |
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| Purification of aldehyde dehydrogenase from rat liver mitochondria by alpha-cyanocinnamate affinity chromatography |
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| Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier |
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| Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans |
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| Rat liver mitochondria prepared in mannitol media demonstrate increased mitochondrial volumes compared with mitochondria prepared in sucrose media. Relationship to the effect of glucagon on mitochondrial function |
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| Reconstitution of the L-lactate carrier from rat and rabbit erythrocyte plasma membranes |
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| Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel |
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| The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation |
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| The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism |
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| The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. |
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| Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate |
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| Reversible and irreversible inhibition, by stilbenedisulphonates, of lactate transport into rat erythrocytes. Identification of some new high-affinity inhibitors |
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| The role of hexokinase in cardioprotection - mechanism and potential for translation |
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| The role of mitochondria in protection of the heart by preconditioning. |
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| The rôle of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes |
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| The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia |
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| Role of the lactate transporter (MCT1) in skeletal muscles |
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| The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore |
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| The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond |
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| The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-Cyano-4-hydroxycinnamate and related compounds |
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| Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1). |
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| Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle |
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| Switching back to normal diet following high-fat diet feeding reduces cardiac vulnerability to ischaemia and reperfusion injury. |
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| Transport of lactate and other monocarboxylates across mammalian plasma membranes |
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| Transport of pyruvate nad lactate into human erythrocytes. Evidence for the involvement of the chloride carrier and a chloride-independent carrier |
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| Tumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308 |
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| UCPs--unlikely calcium porters. |
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| Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure |
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| Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress |
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